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Arthritis, Rheumatoid

More information in Books or onNLM PubMed
Definition: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.  in children   
Examples Arthritis, Juvenile Rheumatoid; Caplan Syndrome; Felty's Syndrome; Rheumatoid Nodule; Rheumatoid Vasculitis; Sjogren's Syndrome; Still's Disease, Adult-Onset 		Other names Rheumatoid Arthritis
 
SubstanceCAS Registry & nameCategoriesSource
Palindromic rheumatism  0   *Arthritis, Rheumatoid.
Sj+¦gren-Mikulicz syndrome  0   *Arthritis, Rheumatoid *Parotitis.
abatacept  0   *Immunoconjugates Arthritis, Rheumatoid Tumor Necrosis Factor-alpha.
Pharma Action Immunosuppressive Agents ; Antirheumatic Agents 		Nat Immunol 2002 Nov;3(11):1056-7ORENCIA; NULOJIX
adalimumab  0   *Antibodies, Monoclonal, Humanized Arthritis, Rheumatoid Tumor Necrosis Factor-alpha.
Pharma Action Anti-Inflammatory Agents ; Antirheumatic Agents 		Ann Rheum Dis 2002 Apr;61(4):311-8HUMIRA
infliximab  0   *Antibodies, Monoclonal Arthritis, Rheumatoid Crohn Disease Tumor Necrosis Factor-alpha.
Pharma Action Anti-Inflammatory Agents ; Dermatologic Agents ; Gastrointestinal Agents ; Antirheumatic Agents 		N Engl J Med 1997 Oct 9;337(15):1029-35REMICADE
TNFR-Fc fusion protein  185243-69-0   *Immunoglobulin G *Receptors, Tumor Necrosis Factor Arthritis, Rheumatoid Recombinant Fusion Proteins Tumor Necrosis Factor-alpha.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Gastrointestinal Agents ; Immunologic Factors ; Immunosuppressive Agents ; Antirheumatic Agents 		J Immunol 1995 Nov 15;155(10):5038-45ENBREL
rituximab  0   *Antibodies, Monoclonal, Murine-Derived Arthritis, Rheumatoid Leukemia Lymphoma, B-Cell Antigens, CD20.
Pharma Action Antineoplastic Agents ; Immunologic Factors ; Antirheumatic Agents 		Oncology (Huntingt) 1994 Dec;8(12):84, 87RITUXAN
RHP protein, human  0   *Blood Proteins Antibodies Arthritis, Rheumatoid Complement Activating Enzymes Biological Markers. Biochem Biophys Res Commun 1985;128(3):1288
OM-8930  81207-56-9 OM 8930  Escherichia coli Adjuvants, Immunologic Arthritis, Rheumatoid/drug therapy. Z Rheumatol 1981;40(5):228

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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