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Egtazic Acid

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Definition: A chelating agent relatively more specific for calcium and less toxic than EDETIC ACID.     
Pharmacological Action Antidotes; Chelating Agents
Other names Ethylene Glycol Tetraacetic Acid; EGTA; Magnesium EGTA; EGTA, Tetrasodium; Acid, Egtazic; Tetrasodium EGTA; Magnesium-EGTA; Glycoletherdiamine-N,N,N',N'-tetraacetic Acid; GEDTA; Ethylenebis(oxyethylenenitrile)tetraacetic Acid; Ethylene Glycol Bis(2-aminoethyl ether)tetraacetic; Egtazic Acid Sodium Salt; Egtazic Acid Potassium Salt; Egtazic Acid Disodium Salt; EGATA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
DP 460  0   Egtazic Acid/*analogs & derivatives. J Neurochem 2007 Aug;102(3):991-1000
o-nitrophenylegtazic acid acetoxymethyl ester  0   Egtazic Acid/*analogs & derivatives. Am J Physiol 1999 Nov;277(5 Pt 1):L893-900
3,12-bis(carboxymethyl)-5-(3-nitrodibenzo(b,d)furan-2-yl)-6,9-Dioxa-3,12-diazatetradecanedioic acid  0   *Benzofurans Egtazic Acid/*analogs & derivatives. Nat Methods 2006 Jan;3(1):35-40
5,5'-dimethyl bis(o-aminophenoxy)ethane-N,N,N',N' tetraacetic acetoxymethyl ester  0   Egtazic Acid/*analogs & derivatives. Metabolism 2002 Jul;51(7):912-8
poly((3,12-bis(carbamoylmethyl)-6,9-dioxa-3,12-diazatetradecanedioate)gadolinium(III)-decyl)  0   *Organometallic Compounds Egtazic Acid/*analogs & derivatives Gadolinium. J Biol Inorg Chem 2001 Mar;6(3):247-55
DP-b99  0   Egtazic Acid/*analogs & derivatives. J Pharm Biomed Anal 2001 Mar;24(5-6):967-75
DP-109  0   Egtazic Acid/*analogs & derivatives. J Pharm Biomed Anal 2001 Mar;24(5-6):967-75
dimethoxynitrophenyl-EGTA-4  0   Egtazic Acid/*analogs & derivatives. Proc Natl Acad Sci U S A 1999 Jan 19;96(2):760-5
5-nitro-1,2-bis(2-aminophenoxy)ethane-N,N,N'N'-tetraacetic acid  0   Egtazic Acid/*analogs & derivatives. Protein Sci 1997 Oct;6(10):2059-71
5,5'-dinitro-1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester  0   Egtazic Acid/*analogs & derivatives. Neuroscience 1996 Nov;75(1):99-109
1,2-bis(2-amino-5,6-difluorophenoxy)ethane-N,N,N',N'-tetraacetic acid  156638-52-7   Egtazic Acid/*analogs & derivatives. Am J Physiol 1994 May;266(5 Pt 1):C1313-22
2-nitrophenyl-EGTA  238073-40-0   Egtazic Acid/*analogs & derivatives. Proc Natl Acad Sci U S A 1994 Jan 4;91(1):187-91
diazo-4  123330-72-3   Diazomethane/*analogs & derivatives Egtazic Acid/*analogs & derivatives. J Physiol (Lond) 1993 May;464:501-28
1,2-bis(2-(1-hydroxycarbonyl)ethyl-(hydoxycarbonylmethyl)amino-5-fluorophenoxy)ethane  149249-70-7   Egtazic Acid/*analogs & derivatives. Biochem J 1993 Jul 15;293(Pt 2):407-11
1,2-bis(2-aminophenoxy)ethane-4,4'-difluoro-N,N,N',N'-tetraacetic acid acetoxymethyl ester  0   Egtazic Acid/*analogs & derivatives. Eur J Pharmacol 1993 Mar 16;233(1):13-20
1,2-bis(2-aminophenoxy)ethane-5,5'-difluoro-N,N,N',N'-tetraacetic acid acetoxymethyl ester  0   Egtazic Acid/*analogs & derivatives. Eur J Pharmacol 1993 Mar 16;233(1):13-20
1,2-bis(2-aminophenoxy)ethane-5,5'-dibromo-N,N,N',N'-tetraacetic acetoxymethyl ester  0   Egtazic Acid/*analogs & derivatives. Eur J Pharmacol 1993 Mar 16;233(1):13-20
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester  139890-68-9   Egtazic Acid/*analogs & derivatives.
Pharma Action Chelating Agents
FASEB J 1991;5(11):2586
5,5'-dimethyl-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetate  91416-19-2   Egtazic Acid/*analogs & derivatives.
Pharma Action Chelating Agents
Proc Natl Acad Sci USA 1989;86(1):167
5,5'-dibromo-1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid  111248-72-7   Egtazic Acid/*analogs & derivatives. Biochim Biophys Acta 1987;925(2):133
nitr 7  109267-14-3 Glycine, N-(2-((2-(2-(bis(carboxymethyl)amino)-5-(hydroxy(6-nitro-1,3-benzodioxol-5-yl)methyl)phenoxy)cyclopentyl)oxy)-4-methylphenyl)-N-(carboxymethyl)-, cis  Egtazic Acid/*analogs & derivatives. Proc Natl Acad Sci USA 1987;84(10):3496
nitr 5  109232-36-2 Glycine, N-(2-(2-(2-(bis(carboxymethyl)amino)-5-(hydroxy(6-nitro-1,3-benzodioxol-5-yl)methyl)phenoxy)ethoxy)-4-methylphenyl)-N-(carboxymethyl)  Egtazic Acid/*analogs & derivatives.
Pharma Action Chelating Agents
Proc Natl Acad Sci USA 1987;84(10):3496
nitr 2  103471-64-3 Glycine, N-(2-(2-(2-(bis(carboxymethyl)amino)-5-(methoxy(6-nitro-1,3-benzodioxol-5-yl)methyl)phenoxy)ethoxy)-4-methylphenyl)-N-(carboxymethyl)  Egtazic Acid/*analogs & derivatives. Biophys J 1986;50(5):843
EGTA acetoxymethyl ester  99590-86-0   Egtazic Acid/*analogs & derivatives. Acta Physiol Hung 1985;66(2):189
EGTA ethyl ester  99590-87-1   Egtazic Acid/*analogs & derivatives. Acta Physiol Hung 1985;66(2):189
5,5'-difluoro-1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid  85233-21-2 Glycine, N,N'-(1,2-ethanediylbis(oxy(5-fluoro-2,1-phenylene)))bis(N-(carboxymethyl))  Egtazic Acid/*analogs & derivatives.
Pharma Action Chelating Agents
Proc Natl Acad Sci USA 1983;80(23):7178
4,4'-difluoro-1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid  85233-22-3   Egtazic Acid/*analogs & derivatives. Proc Natl Acad Sci USA 1983;80(23):7178
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid  85233-19-8 Glycine, N,N'-(1,2-ethanediylbis(oxy-2,1-phenylene))bis(N-(carboxymethyl))-,tetrapotassium salt  Egtazic Acid/*analogs & derivatives.
Pharma Action Chelating Agents ; Indicators and Reagents
Biochemistry 1980;19(11):2396

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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