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Histones

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Definition: Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.  H1, H2a, H2b, H3, etc. go here    Other names Histone H7; Histone H5; Histone H4; Histone H3.3; Histone H3; Histone H2b; Histone H2a; Histone H1(s); Histone H1; Histone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
H1.1 protein, human  0   *Histones. Cell Sci. 2011 Oct 1;124(Pt 19):3254-65
oncohist  0   *Histones *Recombinant Proteins. J Pharm Biomed Anal 2010 Sep 21;53(1):29-36
H2A.Z protein, Arabidopsis  0   *Histones *Arabidopsis Proteins. Nature. 2010 Feb 18;463(7283):887-8
Brpf1 protein, zebrafish  0   *Carrier Proteins *Nuclear Proteins *Zebrafish Proteins Histones. Development 2008 Jun;135(11):1935-46
lysyl-glycyl-histidyl-tyrosyl-alanyl-glutamyl-arginyl-valyl-glyine  0   *Histones *Peptide Fragments. Toxicol Appl Pharmacol 2008 Jun 15;229(3):342-50
H2AFX protein, mouse  0   *Histones. Nature 2008 Jan 24;451(7177):460-4
H1FNT protein, human  0   *Histones. Int J Androl 2006 Apr;29(2):353-9
HupB protein, Mycobacterium tuberculosis  0   *Bacterial Proteins *Histones. Infect Immun 1999 Dec;67(12):6510-7
gammaH2AX protein, S cerevisiae  0   *Histones *Saccharomyces cerevisiae Proteins. Nature 2006 Jan 26;439(7075);497-501
Mst77F protein, Drosophila  0   *Histones *Drosophila Proteins. Mol Cell Biol 2005 Jul;25(14):6165-77
Hils1 protein, mouse  0   *DNA-Binding Proteins Histones. Int J Androl 2003 Dec;26(6):354-65
Htz1 protein, S cerevisiae  0   *Histones *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2004 Nov;24(21):9424-36
Hist1h1e protein, mouse  0   *Histones. J Biol Chem 1993 Jan 5;268(1):713-8
Mbd2 protein, mouse  0   *DNA-Binding Proteins Histones.
MBD2 protein, human  0   *DNA-Binding Proteins Histones.
Mbd1 protein, rat  0   *DNA-Binding Proteins Histones.
Mbd1 protein, mouse  0   *DNA-Binding Proteins Histones.
HHO1 protein, S cerevisiae  0   *Histones *Saccharomyces cerevisiae Proteins. Nucleic Acids Res 2003 Dec 15;31(24):7199-207
H2AX protein, mouse  0   *Histones. J Exp Med. 2003 Jun 16;197(12):1767-78
gamma-H2AX protein, mouse  0   *Histones. Biol Reprod 2003 Feb;68(2):628-34
H1FOO protein, human  0   *Egg Proteins *Histones. Biochem Biophys Res Commun 2003 May 2;304(2):351-7
LNP18 protein, Leishmania major  0   *Histones. Infect Immun 2002 Dec;70(12):6976-86
H1.X protein, C elegans  0   *Histones *Caenorhabditis elegans Proteins. J Cell Sci 2002 Jul 15;115(Pt 14):2881-91
H2AFX protein, human  0   *Histones Phosphoproteins. Nucleic Acids Res 1989 Nov 25;17(22):9113-26
histone hairpin-binding protein, C elegans  0   *RNA-Binding Proteins *Caenorhabditis elegans Proteins Histones. J Cell Sci 2002 Feb 15;115(Pt 4):857-66
H1' protein (22-42)  0   *Histones. Biochem Biophys Res Commun 2002 Feb 15;291(1):2530-7
SU(VAR)3-9  EC 2.1.1.-   *Methyltransferases Histones. EMBO Rep 2001 Oct;2(10):915-9
H2AFY2 protein, human  0   *Histones. J Biol Chem 2001 Jun 15;276(24):21776-84
Cid protein, Drosophila  0   *DNA-Binding Proteins *Histones *Drosophila Proteins. Genetics 2001 Mar;157(3):1293-8
H1foo protein, mouse  0   *Histones. Development 2001 Mar;128(5):655-64
p35 histone  0   *Histones Plant Proteins. Chromosoma 1999 Jul;108(3):190-9
macroH2A histone  0   *Histones. Nucleic Acids Res 1998 Jun 15;26(12):2837-42
HIST1H1B protein, human  0   *Histones. Gene 1997 Jan 15;184(2):141-8
His4r protein, Drosophila  0   *Histones *Drosophila Proteins. FEBS Lett 1996 Jun 17;388(2-3):219-22
han1A protein, Thermococcus zilligii  0   *Histones *Archaeal Proteins. Biochim Biophys Acta 1996 Jun 3;1307(1):1-7
KAP4 protein, Crithidia fasciculata  0   *Histones *Protozoan Proteins. Mol Cell Biol 1996 Feb;16(2):564-76
KAP3 protein, Crithidia fasciculata  0   *Histones *Protozoan Proteins. Mol Cell Biol 1996 Feb;16(2):564-76
KAP2 protein, Crithidia fasciculata  0   *Histones *Protozoan Proteins DNA, Kinetoplast. Mol Cell Biol 1996 Feb;16(2):564-76
histone HMf  0   *Histones. Biochemistry 1995 Jul 4;34(26):8441-8
CSE4 protein, S cerevisiae  0   *Chromosomal Proteins, Non-Histone *DNA-Binding Proteins *Saccharomyces cerevisiae Proteins Chromatin Histones. Genes Dev 1995 Mar 1;9(5):573-86
PHT1 protein, S pombe  0   *Histones *Schizosaccharomyces pombe Proteins. Mol Gen Genet 1994 Dec 1;245(5):628-35
M1 protein, Lilium longiflorum  0   *Plant Proteins Histones. Chromosomes 1994 Jul;103(4):251-61
HPyA2 protein, Pyrococcus  0   *Histones *Archaeal Proteins. Gene 1994 Dec 1;150(1):207-8
HPyA1 protein, Pyrococcus  0   *Histones *Archaeal Proteins. Gene 1994 Dec 1;150(1):207-8
Hc1 protein, Chlamydia trachomatis  0   *DNA-Binding Proteins *Protozoan Proteins *RNA-Binding Proteins Crithidia Histones. Mol Microbiol 1994 Mar;11(6):1085-98
HctB protein, Chlamydia trachomatis  0   *Bacterial Proteins *DNA-Binding Proteins *Histones. J Bacteriol 1993 Jul;175(14):4274-81
histone H2B type 1-A  0   *Histones. Biol Reprod 1993 May;48(5):1047-56
histone H2A.F-Z  0   *Histones. Dev Biol 1992 Oct;153(2):402-6
osteogenic growth peptide  132996-61-3 Glycine, L-alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-threonyl-L-leucyl-L-tyrosylglycyl-L-phenylalanylglycyl  *Histones *Intercellular Signaling Peptides and Proteins. EMBO J 1992 May;11(5):1867-73
EM6 protein, Ensis minor  0   *Histones. Biochim Biophys Acta 1992 Mar 12;1119(3):296-302
EM5 protein, Ensis minor  0   *Histones. Biochim Biophys Acta 1992 Mar 12;1119(3):296-302
HMf protein, Archaeal  0   *Histones *Archaeal Proteins. Proc Natl Acad Sci USA 1990;87(15):5788
nuclear protein B4, Xenopus laevis  0   *Nuclear Proteins Histones. Genes Dev 1988;2(10):1284
VegA protein, Myxococcus xanthus  0   *Histones *Bacterial Proteins. J Mol Biol 1987;196(3):517
N1/N2 protein, Xenopus  0   *Carrier Proteins *Nuclear Proteins Histones. EMBO J 1986;5(13):3547
basic protein phi(0)  0   *Histones. Exp Cell Res 1983;148(2):331
poly(ADP-ribosylated) histone H1  0   *Histones. Anal Biochem 1981;114(2):330
butyrate-enhanced protein, Chinese hamster  0   *Histones. Biochemistry 1980;19(18):4331
histone H1 phosphate  0   *Histones. Biochemistry 1980;19(10):2240
nuclear protein H1(0)  0   *Histones. FEBS Lett 110(1):25;1980
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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