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Intermediate Filament Proteins

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Definition: Filaments 7-11 nm in diameter found in the cytoplasm of all cells. Many specific proteins belong to this group, e.g., desmin, vimentin, prekeratin, decamin, skeletin, neurofilin, neurofilament protein, and glial fibrillary acid protein.  /biosyn /drug eff /physiol permitted   
Examples Desmin; Glial Fibrillary Acidic Protein; Keratins; Neurofilament Proteins; Vimentin
Other names Fibroblast Intermediate Filament Proteins; Proteins, Intermediate Filament; Filament Proteins, Intermediate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
synemin protein, rat  0   *Intermediate Filament Proteins. FASEB J. 2012 Jan;26(1):137-48
IFB-1 protein, C elegans  0   *Intermediate Filament Proteins *Caenorhabditis elegans Proteins. Dev Cell 2009 Nov;17(5):724-35
KAP25.1 protein, human  0   *Intermediate Filament Proteins. Br J Dermatol 2008 Sep;159(3):725-9
KAP27.1 protein, human  0   *Intermediate Filament Proteins. Br J Dermatol 2008 Sep;159(3):725-9
KAP26.1 protein, human  0   *Intermediate Filament Proteins. Br J Dermatol 2008 Sep;159(3):725-9
IFC-2 protein, C elegans  0   *Intermediate Filament Proteins. Differentiation 2008 Oct;76(8):881-96
eIF6 protein, Xenopus  0   *Carrier Proteins *Xenopus Proteins *Intermediate Filament Proteins Peptide Initiation Factors. Cell Mol Life Sci 2005 Jul;62(14):1641-52
Hrnr protein, mouse  0   *Calcium-Binding Proteins *Intermediate Filament Proteins.
HRNR protein, human  0   *Calcium-Binding Proteins *Intermediate Filament Proteins.
RGD1307660 protein, rat  0   *Calcium-Binding Proteins *Intermediate Filament Proteins.
SYNC protein, human  0   *Intermediate Filament Proteins *Muscle Proteins.
Sync protein, mouse  0   *Intermediate Filament Proteins *Muscle Proteins.
synemin protein, mouse  0   *Intermediate Filament Proteins. Exp Cell Res 2004 Aug 15;298(2):431-44
TCHH protein, human  0   *Antigens *Intermediate Filament Proteins. FASEB J 2003 Nov;17(14):2037-47
RANDAM-2 protein, mouse  0   *Intermediate Filament Proteins. J Neurosci Res 2002 Mar 1;67(5):595-606
RANDAM-1 protein, mouse  0   *Intermediate Filament Proteins. J Neurosci Res 2002 Mar 1;67(5):595-606
FS39 protein, mouse  0   *Intermediate Filament Proteins. Biol Reprod 2001 Jul;65(1):277-87
desmuslin  0   *Intermediate Filament Proteins Muscle Proteins. Proc Natl Acad Sci U S A 2001 May 22;98(11):6156-61
VIP54 protein, Helicobacter pylori  0   *Bacterial Proteins *Intermediate Filament Proteins. EMBO J 2000 Jan 4;19(1):48-56
gliarin protein, Hirudo medicinalis  0   *Intermediate Filament Proteins Nerve Tissue Proteins. J Neurobiol 1999 Aug;40(2):244-53
macrolin protein, Hirudo medicinalis  0   *Intermediate Filament Proteins Nerve Tissue Proteins. J Neurobiol 1999 Aug;40(2):244-53
Noc1 protein, S pombe  0   *Heat-Shock Proteins *Intermediate Filament Proteins *Schizosaccharomyces pombe Proteins. Biochim Biophys Acta 1998 Jul 30;1399(1):67-72
NES protein, chicken  0   *Intermediate Filament Proteins *Nerve Tissue Proteins. Brain Res Dev Brain Res 1997 Jul 18;101(1-2):225-38
filarin protein, Haemopis marmorata  0   *Intermediate Filament Proteins *Nerve Tissue Proteins. J Neurobiol 1995 Jun;27(2):227-39
FSP1 protein, human  0   *Calcium-Binding Proteins Intermediate Filament Proteins. J Cell Biol 1995 Jul;130(2):393-405
intermediate filament protein 1, Onchocerca volvulus  0   *Antigens, Helminth *Intermediate Filament Proteins Antigens, Helminth. Int J Parasitol 1994 Apr;24(2):299-301
gefiltin protein, Carassius auratus  0   *Intermediate Filament Proteins *Fish Proteins. EMBO J 1994 Jan 15;13(2):297-305
phakinin  0   *Eye Proteins *Intermediate Filament Proteins. J Cell Biol 1993 Dec;123(6 Pt 1):1507-16
filensin  0   *Eye Proteins *Intermediate Filament Proteins. J Cell Sci 1992 Nov;103(Pt 3):709-18
tanabin protein, Xenopus  148970-47-2   *Intermediate Filament Proteins *Nerve Tissue Proteins *Xenopus Proteins. Neuron 1992 Sep;9(3):417-28
intermediate filament protein, Branchiostoma lanceolatum  148197-21-1   *Intermediate Filament Proteins. Eur J Cell Biol 1992 Jun;58(1):128-35
MDM1 protein, S cerevisiae  0   *Intermediate Filament Proteins *Saccharomyces cerevisiae Proteins. J Cell Biol 1992 Jul;118(2):385-95
neurofilament protein NF 60  143221-01-6   *Intermediate Filament Proteins Nerve Tissue Proteins. J Biol Chem 1991;266(23):15035
neurofilament protein NF 70  143221-02-7   *Intermediate Filament Proteins Nerve Tissue Proteins. J Biol Chem 1991;266(23):15035
nestin  0   *Intermediate Filament Proteins *Nerve Tissue Proteins. Cell 1990;60(4):585
intermediate filament protein component 7c, Ovis aries  0   *Intermediate Filament Proteins. Biochem J 1989;261(3):1015
alpha-internexin  0   *Intermediate Filament Proteins Nerve Tissue Proteins. J Cell Biol 1985;101(4):1316
peripherin  0   *Intermediate Filament Proteins *Membrane Glycoproteins *Nerve Tissue Proteins Retinal Degeneration Xenopus Proteins. Dev Neurosci 1983-84;6(6):335
epinemin  0   *Intermediate Filament Proteins. J Cell Biol 1983;97(6):1891
intermediate filament protein p50  0   *Intermediate Filament Proteins. J Cell Biol 1983;97(5 pt 1):1507
decamin  0   *Intermediate Filament Proteins. Proc Natl Acad Sci USA 1981;78(6):3692
filaggrin  0   *Intermediate Filament Proteins Phosphoproteins Protein Precursors. Curr Probl Dermatol 1980;10:311; Proc Natl Acad Sci USA 1981;78(7):4097
trichohyalin  0   *Intermediate Filament Proteins. Biochim Biophys Acta 495:159;1977; Int Rev Cytol 1979;60:331
prekeratin  0   *Keratins *Protein Precursors Intermediate Filament Proteins. Br J Dermatol 92:647;1975; Exp Cell Res 118(1):95;1979; J Biol Chem 248(13):4280;1973; J Cell Biol 1980;84(3):633; J Invest Dermatol 67:521;1976; Proc Natl Acad Sci USA 75(10):5034;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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