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Heat-Shock Proteins

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Definition: Proteins which are synthesized in eukaryotic organisms and bacteria in response to hyperthermia and other environmental stresses. They increase thermal tolerance and perform functions essential to cell survival under these conditions.     
See Also Cold Shock Proteins and Peptides; Heat-Shock Response
Examples Chaperonins; Heat-Shock Proteins, Small; HSP40 Heat-Shock Proteins; HSP47 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins 		Other names Stress Proteins; Heat Shock Proteins; Heat Shock Protein; Heat-Shock Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
UspB protein, Salmonella enterica  0   *Bacterial Proteins *Heat-Shock Proteins. Vet Microbiol. 2011 Nov 21;153(1-2):186-90
Hsf2 protein, rat  0   *Heat-Shock Proteins *Transcription Factors. J Neurosci. 1996 Jan 15;16(2):478-85.
TcSTI-1 protein, Trypanosoma cruzi  0   *Heat-Shock Proteins. Mem Inst Oswaldo Cruz. 2011 Feb;106(1):70-7
HSPB3 protein, mouse  0   *Heat-Shock Proteins. J Neurosci Res. 2011 Feb;89(2):267-73
Hsp67Bc protein, Drosophila  0   *Heat-Shock Proteins *Drosophila Proteins. J Biol Chem 2010 Nov 26;285(48):37811-22
SESN3 protein, mouse  0   *Heat-Shock Proteins. Dev Cell. 2010 Apr 20;18(4):592-604
HSF3 protein, mouse  0   *Heat-Shock Proteins *Transcription Factors. Mol Biol Cell 2010 Jan;21(1):106-16
HSP104 protein, S pombe  EC 3.6.1.-   *Adenosine Triphosphatases *Heat-Shock Proteins. PLoS One 2009;4(9):e6939
HSPB3 protein, rat  0   *Heat-Shock Proteins. J Mol Biol 2009 Nov 13;393(5):1022-32
BOBBER1 protein, Arabidopsis  0   *Heat-Shock Proteins *Arabidopsis Proteins. Plant Physiol 2009 Sep;151(1):241-52
RRS1 protein, mouse  0   *Heat-Shock Proteins. J Biol Chem 2009 Jul 3;284(27):18167-73
CSP3 protein, Arabidopsis  0   *Heat-Shock Proteins *Arabidopsis Proteins Molecular Chaperones. J Biol Chem 2009 Aug 28;284(35):23454-60
STI-1 protein, C elegans  0   *Heat-Shock Proteins *Caenorhabditis elegans Proteins. J Mol Biol. 2009 Jul 24;390(4):604-17
STI1 protein, S cerevisiae  0   *Heat-Shock Proteins *Saccharomyces cerevisiae Proteins.
universal stress protein A, E coli  0   *Heat-Shock Proteins *Escherichia coli Proteins. J Mol Biol 2009 Feb 13;386(1):134-48
ClpC1 protein, Mycobacterium tuberculosis  0   *Bacterial Proteins *Heat-Shock Proteins. FEBS J. 2008 Dec;275(24):6149-58
Hsp104 protein, rat  0   *Heat-Shock Proteins. J Clin Invest 2008 Sep;118(9):3087-97
Hsf2 protein, mouse  0   *Heat-Shock Proteins *Transcription Factors. Proc Natl Acad Sci U S A 2008 Aug 12;105(32):11224-9
crystallin alpha-B protein, rat  0   *Crystallins *Microtubule-Associated Proteins Heat-Shock Proteins. Eur J Biochem 1991 Dec 18;202(3):775-81
Dnj-11 protein, C elegans  0   *Heat-Shock Proteins *Caenorhabditis elegans Proteins DNA-Binding Proteins. PLoS Biol 2008 Apr 8;6(4):e84
HSP23.6 protein, Arabidopsis  0   *Heat-Shock Proteins *Arabidopsis Proteins Mitochondrial Proteins. Genome 2008 Mar;51(3):177-86
HSP16.1 protein, C elegans  0   *Heat-Shock Proteins *Caenorhabditis elegans Proteins. Bioelectromagnetics 2008 Feb;29(2):92-9
HsfA9 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins DNA-Binding Proteins Heat-Shock Proteins. Plant Cell 2007 Jan;19(1):182-95
Srr2 protein, S pombe  0   *Heat-Shock Proteins *Schizosaccharomyces pombe Proteins. J Biol Chem 2007 Mar 23;282(12):8793-800
HSF2 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins Heat-Shock Proteins. Biochimie. 2006 Dec;88(12):1983-8
HSF4 protein, rat  0   *Heat-Shock Proteins *Transcription Factors. Biochem Biophys Res Commun 2007 Feb 16;353(3):679-85
CSDP1 protein, Arabidopsis  0   *DNA-Binding Proteins *Arabidopsis Proteins Heat-Shock Proteins Zinc Fingers. Nucleic Acids Res 2007;35(2):506-12
HspA12B protein, zebrafish  0   *Heat-Shock Proteins *Zebrafish Proteins. J Cell Sci 2006 Oct 1;119(Pt 19):4117-26
Hit1 protein, Arabidopsis  0   *Arabidopsis Proteins Heat-Shock Proteins. Planta 2006 Jul;224(2):330-8
YhbO protein, E coli  0   *Heat-Shock Proteins *Escherichia coli Proteins. Protein Expr Purif. 2006 Jun;47(2):455-60
Hsp15.7 protein, Arabidopsis  0   *Heat-Shock Proteins *Arabidopsis Proteins. Plant Physiol 2006 May;141(1):47-60
Hsa32 protein, Arabidopsis  0   *Heat-Shock Proteins *Arabidopsis Proteins. Plant Physiol 2006 Apr;140(4):1297-305
Abu-11 protein, C elegans  0   *Heat-Shock Proteins *Caenorhabditis elegans Proteins. Dev Cell 2005 Nov;9(5):605-15
HspQ protein, E coli  0   *Heat-Shock Proteins *Escherichia coli Proteins. Genes Cells 2004 Dec;9(12):1151-66
Hsp-4 protein, C elegans  0   *Heat-Shock Proteins *Caenorhabditis elegans Proteins. FEBS Lett 2005 Jun 6;579(14):3063-8
Hsp-3 protein, C elegans  0   *Heat-Shock Proteins *Caenorhabditis elegans Proteins. FEBS Lett 2005 Jun 6;579(14):3063-8
Hspa9b protein, zebrafish  0   *Heat-Shock Proteins *Zebrafish Proteins. Blood 2005 May 1;105(9):3528-34
YciF protein, E coli  0   *Heat-Shock Proteins *Escherichia coli Proteins. Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 2):2389-90
heat-shock protein 65, human  0   *Heat-Shock Proteins. Circulation 2004 Oct 26;110(17):2588-90
HSP26 protein, S cerevisiae  0   *Heat-Shock Proteins *Saccharomyces cerevisiae Proteins.
Trp53inp1 protein, rat  0   *Heat-Shock Proteins *Nuclear Proteins.
Trp53inp1 protein, mouse  0   *Carrier Proteins *Heat-Shock Proteins Apoptosis.
Sacs protein, mouse  0   *Heat-Shock Proteins.
CspA protein, E coli  0   *Heat-Shock Proteins *Escherichia coli Proteins. Proc Natl Acad Sci U S A 2005 Feb 1;102(5):1396-401
YciE protein, E coli  0   *Heat-Shock Proteins *Escherichia coli Proteins. Acta Crystallogr D Biol Crystallogr 2004 Oct;60(Pt 10):1888-9
heat-shock factor 2, Xenopus  0   *Heat-Shock Proteins *Transcription Factors *Xenopus Proteins. Cell Stress Chaperones 2004 Summer;9(2);214-20
YDR533c protein, S cerevisiae  EC 3.4.22.-   *Heat-Shock Proteins *Saccharomyces cerevisiae Proteins Cysteine Endopeptidases. Structure (Camb) 2004 May;12(5):839-47
HSFX1 protein, human  0   *DNA-Binding Proteins *Heat-Shock Proteins. Biol Reprod. 2004 Jul;71(1):297-306
rTid-1 protein, rat  0   *Heat-Shock Proteins. Mol Cell Biochem. 2004 Mar;258(1-2):183-9
HSP33 protein, E coli  0   *Heat-Shock Proteins *Escherichia coli Proteins.
F08H9.3 protein, C elegans  0   *Heat-Shock Proteins *Caenorhabditis elegans Proteins.
F08H9.4 protein, C elegans  0   *Heat-Shock Proteins *Caenorhabditis elegans Proteins.
hsp16 protein, S pombe  0   *Heat-Shock Proteins *Schizosaccharomyces pombe Proteins.
ERP29 protein, human  0   *Heat-Shock Proteins Endoplasmic Reticulum.
Erp29 protein, mouse  0   *Heat-Shock Proteins Endoplasmic Reticulum.
CspB protein, E coli  0   *Carrier Proteins *Heat-Shock Proteins *Escherichia coli Proteins.
Rab16A protein, Hordeum vulgare  0   *Heat-Shock Proteins *Plant Proteins.
TIR1 protein, S cerevisiae  0   *Heat-Shock Proteins *Saccharomyces cerevisiae Proteins.
Sqstm1 protein, rat  0   *Heat-Shock Proteins.
HRSP12 protein, human  0   *Heat-Shock Proteins *Ribonucleases.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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