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Oxepins

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Definition: Compounds based on a 7-membered heterocyclic ring including an oxygen. They can be considered a medium ring ether. A natural source is the MONTANOA plant genus. Some dibenzo-dioxepins, called depsidones, are found in GARCINIA plants.     
Examples Doxepin 		Other names Oxepin; Oxepenes; Oxepene
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
protuboxepin A  0   *Oxepins Alkaloids. J Nat Prod. 2011 May 27;74(5):1284-7
protuboxepin B  0   *Oxepins Alkaloids. J Nat Prod. 2011 May 27;74(5):1284-7
psammaplysin H  0   *Isoxazoles *Oxepins. Bioorg Med Chem Lett 2011 Jan 15;21(2):846-8
dibenz(b,f)oxepin  0   *Oxepins. Nat Prod Commun. 2011 Jan;6(1):53-4
livistone B  0   *Lactones *Oxepins *Depsides. J Asian Nat Prod Res 2009;11(3):243-9
livistone A  0   *Oxepins *Lactones *Depsides. J Asian Nat Prod Res 2009;11(3):243-9
stictic acid  0   *Heterocyclic Compounds with 4 or More Rings *Oxepins. J Nat Prod 2007 Jul;70(7):1218-20
grandiuvarone A  0   *Oxepins. J Nat Prod 2006 Apr;69(4):692-4
2-N,N-dimethylaminomethyl-2,3,3a,12b-tetrahydrodibenzo(b,f)furo(2,3-d)oxepin  0   *Oxepins *Benzofurans. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2898-901
rogioloxepane A  0   *Oxepins. Org Lett. 2003 Aug 21;5(17):3009-11
dihydrocoriamyrtin  0   *Lactones *Oxepins. Yao Xue Xue Bao 1998 Sep;33(9):688-92
1-phenyl-1,4-epoxy-1H,4H-naphtho(1,8-de)(1,2)dioxepin  0   *Naphthalenes *Oxepins. Int J Cancer 2002 Jul 10;100(2):220-7
fusidienol  157173-61-0   *Chromones *Oxepins. J Med Chem 2002 Mar 28;45(7):1460-5
zoapatanol  0   *Oxepins Montanoa.
dibenzo(b,f)oxepin-10-ylmethyl-methyl-prop-2-ynyl-amine  0   *Oxepins. J Biol Chem 1998 Mar 6;273(10):5821-8
pterulone  0   *Benzofurans *Oxepins NAD(P)H Dehydrogenase (Quinone)/antagonists & inhibitors. J Antibiot (Tokyo) 1997 Apr;50(4):330-3
pterulinic acid  0   *Benzofurans *Oxepins NAD(P)H Dehydrogenase (Quinone)/antagonists & inhibitors. J Antibiot (Tokyo) 1997 Apr;50(4):330-3
kessyl glycol diacetate  13835-51-3   *Oxepins. Chem Pharm Bull (Tokyo) 1992 Mar;40(3):758-61
montanol  71117-50-5   *Oxepins Plant Extracts. Arch Invest Med (Mex) 1985;16(2):209
monatanol  67359-27-7   *Oxepins. J Reprod Med 1981;26(10)):524
oxepin epoxide  52748-31-9   *Oxepins. J Am Chem Soc 98(20):6350;1976
acetylaranotin  20485-01-2   *Oxepins Sulfhydryl Reagents. Antimicrob Ag Chemother 5(1):19;1974; J Org Chem 42(6):948;1977
depsidone  3580-77-6 11H-dibenzo-(b,e)(1,4)dioxepin-11-one  *Lactones *Depsides Oxepins. Acta Chem Scand 26(2):455;1972; J Nat Prod 64:147;2001

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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