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Oxygenases

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Definition: Oxidases that specifically introduce DIOXYGEN-derived oxygen atoms into a variety of organic molecules.     
Examples Dioxygenases; Inositol Oxygenase; Mixed Function Oxygenases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PHYHD1A protein, human  EC 1.13.-   *Oxygenases. Biochem Biophys Res Commun 2011 May 20;408(4):553-8
apocarotenal oxygenase, Synechocystis  EC 1.13.-   *Oxygenases. Science 2005 Apr 8;308(5719):267-9
DAF-36 protein, C elegans  EC 1.13.-   *Oxygenases. Dev Cell 2006 Apr;10(4):473-82
carotenoid oxygenase  EC 1.13.-   *Oxygenases. Mol Microbiol 2005 Feb;55(4):1015-24
PcpA protein, Sphingomonas  EC 1.13.   *Bacterial Proteins *Oxygenases.
vioC protein, Chromobacterium violaceum  EC 1.13.-   *Bacterial Proteins *Oxygenases *Nonheme Iron Proteins. Chembiochem. 2004 Sep 6;5(9):1274-7
MIOX protein, human  EC 1.13.99.1   *Oxygenases.
ACD1 protein, Arabidopsis  EC 1.13.-   *Oxygenases *Arabidopsis Proteins *Apoptosis Regulatory Proteins. Plant Cell Physiol 2003 Dec;44(12):1266-74
IsdG protein, Staphylococcus aureus  EC 1.14.-   *Oxygenases. J Biol Chem 2004 Jan 2;279(1):436-43
beta,beta-carotene 9',10'-dioxygenase, mouse  EC 1.14.99.36   *Oxygenases. J Nutr 2004 Jan;134(1);246S-250S
RMS1 protein, pea  EC 1.13.-   *Oxygenases. Genes Dev 2003 Jun 15;17(12):1469-74
MAX4 protein, Arabidopsis  EC 1.13.-   *Oxygenases *Arabidopsis Proteins. Genes Dev 2003 Jun 15;17(12):1469-74
dihydroxyacetanilide epoxidase  EC 1.14.99.-   *Oxygenases. Bioorg Med Chem 2002 May;10(5):1221-7
2,4-dichlorophenoxyacetic acid oxygenase class III  EC 1.13.-   *Oxygenases. J Bacteriol 2002 Jan;184(2):509-18
extradiol dioxygenase  EC 1.14.99.-   *Oxygenases. Antonie van Leeuwenhoek 2000 Dec;78(3-4):341-52
cyclododecanone monooxygenase  EC 1.14.13.-   *Oxygenases. J Bacteriol 2001 Nov;183(21):6478-86
iron(II) oxygenase  EC 1.13.-   *Oxygenases. J Am Chem Soc 2001 May 30;123(21):5126-7
DBHR protein, chicken  EC 1.13.-   *Nerve Tissue Proteins *Oxygenases *Avian Proteins Antigens, Differentiation. Plant Mol Biol 2001 Mar;45(5):365-75
flavohemoglobin denitrosylase  EC 1.13.11.-   *Hemeproteins *Oxygenases. J Biol Chem 2001 Mar 9;276(10):7272-7
EmoA protein, bacterium BNC1  EC 1.14.14.-   *Bacterial Proteins *Oxygenases. Appl Environ Microbiol 2001 Feb;67(2):688-95
4-hydroxyacetophenone monooxygenase  EC 1.14.13.-   *Oxygenases. Eur J Biochem. 2001 May;268(9):2547-57
fatty acid alpha-hydroperoxylase  EC 1.13.11.-   *Oxygenases. a metabolite of 19-nor-1,2,5-dihydroxyvitamin D2; structure in first source765-8
epothilone C-D monooxygenase  EC 1.13.12.-   *Oxygenases Epothilones. J Antibiot (Tokyo) 2001 Feb;54(2):144-8
YUC protein, Arabidopsis  EC 1.13.14.-   *Oxygenases *Arabidopsis Proteins. Science 2001 Jan 12;291(5502):306-9
dibenzothiophene sulfone monooxygenase  EC 1.14.99.-   *Oxygenases. Bioseparation 2000;9(3):185-8
adventitous rooting related oxygenase  EC 1.14.11.-   *Oxygenases. J Exp Bot 2000 Oct;51(351):1765-6
PhzO protein, Pseudomonas aureofaciens  EC 1.14.13.-   *Bacterial Proteins *Oxygenases. J Bacteriol 2001 Jan;183(1):318-27
moxY protein, Aspergillus parasiticus  EC 1.113.12.-   *Fungal Proteins *Oxygenases. Appl Microbiol Biotechnol 2000 May;53(5):583-90
etaA protein, Mycobacterium tuberculosis  0   *Oxygenases *Bacterial Proteins. J Biol Chem 2000 Sep 8;275(36):28326-31
monocyclic monoterpeneketone mono-oxygenase  EC 1.14.13.-   *Oxygenases. Biochem J 2000 May 1;347 Pt 3:693-701
phenanthrene dioxygenase  EC 1.14.12.-   *Oxygenases. J Bacteriol 2000 Apr;182(8):2134-41
SPP2 dioxygenase  EC 1.14.1.-   *Oxygenases. Plant Mol Biol 1999 Oct;41(3):371-86
(chloro)hydroquinone 1, 2-dioxygenase  EC 1.14.12.-   *Oxygenases. J Bacteriol 1999 Nov;181(21):6712-9
CYP105D1 protein, Streptomyces griseus  EC 1.14.-   *Bacterial Proteins *Oxygenases Cytochrome P-450 Enzyme System. Biochem Biophys Res Commun 1999 Oct 5;263(3):838-42
linoleate diol synthase  EC 1.14.99.-   *Oxygenases. J Biol Chem 1999 Oct 1;274(40):28219-24
caffeine oxidase  EC 1.14.15.-   *Oxygenases. Biochem Biophys Res Commun 1999 Sep 24;263(2):460-4
1-hydroxy-2-oxolimonene 1,2-monooxygenase  EC 1.14.13.-   *Oxygenases. Appl Environ Microbiol 1999 May;65(5):2092-102
limonene 1,2-monooxygenase  EC 1.14.13.-   *Oxygenases. Appl Environ Microbiol 1999 May;65(5):2092-102
anthocyanidin synthase  EC 1.14.99.-   *Oxygenases Anthocyanins. Plant J 1999 Jan;17(2):181-9
methanesulfonate sulfonatase  EC 1.14.14.-   *Bacterial Proteins *Oxygenases. J Bacteriol 1999 Mar;181(5):1464-73
2,4,5-trihydroxytoluene oxygenase  EC 1.13.11.-   *Oxygenases. J Bacteriol 1999 Feb;181(3):965-72
3,6-diketocamphane monooxygenase  EC 1.14.14.-   *Oxygenases. Acta Crystallogr D Biol Crystallogr 1998 Sep 1;54( Pt 5):1035-8
ethylbenzene dioxygenase  EC 1.-   *Oxygenases. FEMS Microbiol Lett 1998 Sep 15;166(2):171-6
pathogen-induced oxygenase, Nicotiana tabacum  EC 1.14.99.-   *Oxygenases *Plant Proteins. Plant Cell 1998 Sep;10(9):1523-37
chlorophyll a oxygenase  EC 1.13.12.-   *Oxygenases. Proc Natl Acad Sci U S A 1998 Oct 13;95(21):12719-23
nitric oxide dioxygenase  EC 1.14.13.-   *Oxygenases. Proc Natl Acad Sci U S A 1998 Sep 1;95(18):10378-83
toluene 2-xylene monooxygenase  EC 1.14.13.-   *Oxygenases. Appl Environ Microbiol 1998 Aug;64(8):3023-4
2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl oxygenase  EC 1.13.-   *Bacterial Proteins *Oxygenases. Appl Environ Microbiol 1998 Jul;64(7):2520-7
4-nitrophenol monooxygenase  EC 1.14.13.-   *Oxygenases Multienzyme Complexes. Appl Environ Microbiol 1998 Jul;64(7):2479-84
pheide a oxygenase  EC 1.13.-   *Oxygenases. J Biol Chem 1998 Jun 19;273(25):15335-9
3-phenylpropionate dioxygenase  EC 1.14.12.-   *Oxygenases. J Bacteriol 1998 Jun;180(11):2915-23
beta-apocarotenoid-14',13'-dioxygenase  0   *Carotenoids *Oxygenases. Biochemistry (Mosc) 1997 Jul;62(7):787-92
dodA protein, Amanita muscaria  EC 1.14.99.-   *Fungal Proteins *Oxygenases. Mol Gen Genet 1997 Sep;259(1):1-6
dioxin dioxygenase  EC 1.14.99.-   *Oxygenases. Eur J Biochem 1997 Aug 1;247(3):833-42
leucoanthocyanidin dioxygenase  EC 1.14.11.-   *Oxygenases Anthocyanins Flavonoids. Plant Physiol 1997 Apr;113(4):1437-45
choline monooxygenase  EC 1.-   *Oxygenases Iron-Sulfur Proteins Plant Proteins. Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3454-8
3-isopropylcatechol 2,3-dioxygenase  EC 1.-   *Oxygenases. Microbiology 1996 Nov;142( Pt 11):3241-51
3-(2,4--dioxo-6-methyl-5-pyrimidinyl)acrylic acid synthase  EC 1.14.13.-   *Oxygenases. J Bacteriol 1997 Feb;179(4):1385-92
2-nitrotoluene dioxygenase  EC 1.14.12.-   *Oxygenases. Gene 1996 Nov 28;181(1-2):57-61
4-methyl-5-nitrocatechol oxygenase  EC 1.13.12.-   *Flavoproteins *Oxygenases Bacterial Proteins. J Bacteriol 1996 Oct;178(20):6019-24
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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