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Phenothiazines
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Definition
: Compounds containing dibenzo-1,4-thiazine. Some of them are neuroactive.
See Also
Antipsychotic Agents
Examples
Acepromazine
;
Azure Stains
;
Chlorpromazine
;
Fluphenazine
;
Mesoridazine
;
Methotrimeprazine
;
Methylene Blue
;
Moricizine
;
Nonachlazine
;
Perazine
;
Perphenazine
;
Prochlorperazine
;
Promazine
;
Promethazine
;
Thiethylperazine
;
Thioridazine
;
Tolonium Chloride
;
Trifluoperazine
;
Triflupromazine
;
Trimeprazine
Drugs
*
:
PROKETAZINE
Substance
CAS Registry & name
Categories
Source
Drugs
*
2-
amino-
N-
(2-
(4-
(3-
(2-
trifluoromethylphenothiazin-
10-
yl)propyl)piperazin-
1-
yl)-
ethyl)acetamide
0
*Acetamides
*Phenothiazines.
Allergy Asthma Proc. 2011 Sep-Oct;32(5):359-65.
2-
amino-
N-
(2-
(4-
(3-
(2-
trifluoromethylphenothiazin-
10-
yl)propyl)piperazin-
1-
yl)ethyl)acetamide
0
*Phenothiazines
*Piperazines
Serotonin 5-HT2 Receptor Antagonists.
Eur J Pharmacol. 2011 Nov 16;670(1):195-203.
10-
octyl-
3-
(2-
(10-
octyl-
10H-
phenothiazin-
3-
yl)vinyl)-
7-
(2-
(10-
octyl-
3-
(2-
(10-
octyl-
3-
(2-
(10-
octyl-
10H-
phenothiazin-
7-
yl)vinyl)-
10H-
phenothiazin-
7-
yl)vinyl)-
10H-
phenothiazin-
7-
yl)vinyl)-
10H-
phenothiazine
0
*Phenothiazines.
Talanta 2010 Oct 15;82(5):1943-9
10-
octyl-
3-
(2-
(10-
octyl-
3-
(2-
(10-
octyl-
10H-
phenothiazin-
7-
yl)vinyl)-
10H-
phenothiazin-
7-
yl)vinyl)-
10H-
phenothiazine
0
*Phenothiazines.
Talanta 2010 Oct 15;82(5):1943-9
7-
nitro-
1,3-
diaza-
2-
oxophenothiazine
0
*Nitro Compounds
*Phenothiazines.
J Am Chem Soc. 2009 Apr 1;131(12):4288-93
cyamemazine sulfoxide
0
*Cyclic S-Oxides
*Phenothiazines.
J Pharm Pharmacol 2008 Nov;60(11):1507-13
monodesmethyl cyememazine
0
*Phenothiazines.
J Pharm Pharmacol 2008 Nov;60(11):1507-13
N,N-
bis((7-
dimethylamino)phenothiazin-
5-
ium-
3-
yl)-
4,4-
ethylenedipiperidine diiodide
0
*Phenothiazines
*Piperidines.
Org Biomol Chem. 2008 Nov 7;6(21):4026-35
2,3,7,8-
tetrachlorophenothiazine
0
*Phenothiazines
Tetrachlorodibenzodioxin/*analogs & derivatives.
ChemMedChem 2007 Jun;2(6):890-7
RP 12274
0
*Quaternary Ammonium Compounds
*Phenothiazines.
Chembiochem 2008 Apr 14;9(6):849-52
3,7-
bis(N,N-
dibutylamino)phenothiazinium bromide
0
*Phenothiazines.
Photochem Photobiol Sci 2007 Oct;6(10):1067-75
BN 82204
0
*Phenothiazines.
J Neurochem 2006 Aug;98(4):1217-28
2-
cyano-
10-
(3-
(dimethylamino)-
2-
methylpropyl)-
5-
oxide-
phenothiazine
0
*Phenothiazines.
Photochem Photobiol Sci 2006 Mar;5(3):336-42
2-
cyano-
10-
(3-
(dimethylamino,N-
oxide)-
2-
methylpropyl)-
5-
oxide-
phenothiazine
0
*Phenothiazines.
Photochem Photobiol Sci 2006 Mar;5(3):336-42
1,3-
diaza-
2-
oxophenothiazin-
3-
ylacetic acid
0
*Phenothiazines.
Nucleic Acids Res 2004;32(17):5087-95
10-
(N,N-
dimethylaminopentyl)-
2-
(trifluoromethyl) phenothiazine
0
*Phenothiazines.
Drug Metab Dispos. 2003 Jul;31(7):854-60
2-
trifluoromethyl-
10-
(4-
(methylsulfonylamido)butyl)phenothiazine
0
*Phenothiazines
*Sulfonamides.
Cell Mol Biol Lett 2002;7(2):303
10-
(4-
(pyrrolidin-
1-
yl)butyl)phenothiazine
0
*Phenothiazines.
J Med Chem 2002 Jun 20;45(13):2741-8
2-
amino-
10-
(3'-
(1-
methyl-
4-
piperazinyl)propyl)phenothiazine
0
*Phenothiazines
*Piperazines.
J Immunol 2001 Sep 1;167(5):2929-35
6-
methyl-
5-
oxo-
5H-
benzo(a)phenothiazine
0
*Phenothiazines.
Int J Antimicrob Agents 2001 Jul;18(1):67-72
5-
oxo-
5H-
benzo(a)phenothiazine
0
*Phenothiazines.
Int J Antimicrob Agents 2001 Jul;18(1):67-72
3,7-
diaminophenothiazin-
5-
ium
0
*Phenothiazines.
Bioorg Med Chem Lett 2001 Aug 20;11(16):2193-5
OFK 006
0
*Phenothiazines.
Biotechnol Appl Biochem 2000 Aug;32 ( Pt 1) 61-7
oxomemazine
3689-50-7
*Cyclic S-Oxides
*Phenothiazines.
Arch Pharm Res 1994 Dec;17(6):443-51
RP 23618
0
*Phenothiazines
Chemokine CCL5/antagonists & inhibitors.
Bioorg Med Chem Lett 1998 Apr 7;8(7):771-4
4-
bromomethylene violet
0
*Phenothiazines.
Photochem Photobiol 1997 Aug;66(2):245-52
benzophenothiazine
28453-74-9
*Phenothiazines.
Anticancer Res 1997 Jul-Aug;17(4A):2539-43
10-
(4-
chlorobutyl)-
3-
nitrophenothiazine
0
*Phenothiazines.
Acta Crystallogr B 1996 Aug 1;52(Pt 4):713-9
1,3,4-
trifluoro-
2-
nitrophenothiazine
0
*Phenothiazines.
Acta Crystallogr B 1996 Aug 1;52(Pt 4):713-9
10-
(4-
chlorobutyl)-
1,3,4-
trifluoro-
2-
nitrophenothiazine
0
*Phenothiazines.
Acta Crystallogr B 1996 Aug 1;52(Pt 4):713-9
diethazine
60-91-3
*Phenothiazines.
Fortschr Med 1983;101(25):1184
metiazinic acid
13993-65-2
*Phenothiazines.
Sem Hop Paris 1983;59(46):3197
thiopropazate
84-06-0
*Phenothiazines.
mepazine
60-89-9
*Phenothiazines.
acetophenazine
2751-68-0
*Phenothiazines.
TINDAL
fonazine
7456-24-8
*Phenothiazines.
Pharma Action
Histamine H1 Antagonists
azure D2
0
*Phenothiazines.
Eur J Clin Chem Clin Biochem 1995 Sep;33(9):595-601
RP 60180
0
*Phenothiazines.
Prog Neuropsychopharmacol Biol Psychiatry 1995 Jul;19(4):687-97
thioproperazine
316-81-4 10H-
Phenothiazine-
2-
sulfonamide, N,N-
dimethyl-
10-
(3-
(4-
methyl-
1-
piperazinyl)propyl)
*Phenothiazines.
profenamine
522-00-9 10H-
Phenothiazine-
10-
ethanamine, N,N-
diethyl-
alpha-
methyl
*Phenothiazines.
Pharma Action
Histamine Antagonists
;
Adrenergic Antagonists
;
Muscarinic Antagonists
PARSIDOL
pipothiazine
39860-99-6 10H-
Phenothiazine-
2-
sulfonamide,10-
(3-
(4-
(2-
hydroxyethyl)-
1-
piperidinyl)propyl)-
N,N-
dimethyl
*Phenothiazines.
pipothiazine palmitate
37517-26-3 Hexadecanoic acid, 2-
(1-
(3-