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Rifamycins

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Definition: A group of ANTI-BACTERIAL AGENTS characterized by a chromophoric naphthohydroquinone group spanned by an aliphatic bridge not previously found in other known ANTI-BACTERIAL AGENTS. They have been isolated from fermentation broths of Streptomyces mediterranei.     
Pharmacological Action Anti-Bacterial Agents
Examples Rifabutin; Rifampin 		Other names Rifomycins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
salinisporamycin  0   *Rifamycins. J Antibiot (Tokyo) 2009 Sep;62(9):519-26
rifocort  0   *Rifamycins Prednisolone/*analogs & derivatives. Br J Oral Maxillofac Surg 2007 Jan;45(1):27-9
32-hydroxyrifalazil  0   *Rifamycins. Drug Metab Dispos 2008 Oct;36(10):1998-2004
CBR 2092  0   *Rifamycins *Quinolones. Antimicrob Agents Chemother 2008 Jul;52(7):2313-23
ABI 0043  0   *Rifamycins. J Antibiot (Tokyo) 2006 Dec;59(12):804-7
3-amino-4-iminorifamycin S  0   *Rifamycins. Magn Reson Chem 2005 Apr;43(4):269-82
ABI 1131  0   *Rifamycins. Antimicrob Agents Chemother 2003 Mar;47(3):1135-6
ABI 1657  0   *Rifamycins. Antimicrob Agents Chemother 2003 Mar;47(3):1135-6
27-O-demethylrifamycin SV  0   *Rifamycins. Arch Biochem Biophys 2003 Mar 15;411(2):277-88
27-O-demethylrifamycin S  0   *Rifamycins. Arch Biochem Biophys 2003 Mar 15;411(2):277-88
proansamycin B  0   *Rifamycins. J Antibiot (Tokyo) 2002 Apr;55(4):396-406
kanglemycin C  0   *Rifamycins. Chung Kuo Yao Li Hsueh Pao 1999 Jan;20(1):65-8
cytotrienin A  0   *Rifamycins Apoptosis. J Antibiot (Tokyo) 1997 Apr;50(4):370-2
3-(4-cinnamylpiperazinyl iminomethyl)rifamycin SV  0   *Rifamycins. Antimicrob Agents Chemother 1995 Oct;39(10):2320-4
31-homorifamycin W  157049-51-9   *Rifamycins. J Antibiot (Tokyo) 1994 May;47(5):613-5
KRM 1671  148236-03-7 Rifamycin VIII, 25-O-deacetyl-1',4-didehydro-1-deoxy-1,4-dihydro-3'-hydroxy-5'-(4-(2-methylpropyl)-1-piperazinyl)-1-oxo  *Rifamycins. J Chromatogr B Biomed Appl 1994 Mar 4;653(2):177-86
KRM 1668  129791-94-2 Rifamycin VIII, 1',4-didehydro-1-deoxy-1,4-dihydro-3'-hydroxy-5'-(4-(1-methylpropyl)-1-piperazinyl)-1-oxo  *Rifamycins. Antimicrob Agents Chemother 1991;35(3):542
KRM 1657  133633-12-2 Rifamycin VIII, 1',4-didehydro-1-deoxy-1,4-dihydro-3'-hydroxy-1-oxo-5'-(4-propyl-1-piperazinyl)  *Rifamycins. Antimicrob Agents Chemother 1991;35(3):542
KRM 1648  129791-92-0 Rifamycin VIII, 1',4-didehydro-1-deoxy-1,4-dihydro-3'-hydroxy-5'-(4-(2-methylpropyl)-1-piperazinyl)-1-oxo  *Rifamycins.
Pharma Action Antibiotics, Antitubercular ; Leprostatic Agents 		Antimicrob Agents Chemother 1991;35(3):542
FCE 22807  86756-45-8   *Rifamycins. Tubercle 1990;71(2):109
rifamexil  113102-19-5   *Rifamycins. J Med Chem 1990;33(5):1470
Reprimun  132338-78-4   *Rifamycins. Med Interne 1989;27(3):225
3-((dimethylhydrazono)methyl)rifamycin SV  13292-34-7   *Rifamycins. Chem Pharm Bull (Tokyo) 1988;36(10):4157
SPA-S 565  94168-98-6   *Rifamycins. Farmaco (Sci) 1988;43(7-8):619
3-formyl-25-desacetylrifamycin  16783-97-4   *Rifamycins. J Chromatogr 1988;426(2):412
CGP 29861  122188-46-9   *Rifamycins. Tubercule 1987;68(3):177
CGP 27557  122188-45-8   *Rifamycins. Tubercle 1987;68(3):177
CGP 7040  122188-44-7   *Rifamycins. Tubercle 1987;68(3):177
kanglemycin A  114153-91-2 Rifamycin, 20-(1-(3-carboxy-2,2-dimethyl-1-oxopropoxy)ethyl)-20-demethyl-27-O-demethyl-1,4-dideoxy-27-O-(2,6-dideoxy-3,4-O-methylene-beta-D-ribo-hexopyranosyl)-1,4-dihydro-1,4-dioxo  *Rifamycins. J Antibiot (Tokyo) 1988;41(2):264
CGP 4832  113303-81-4 Rifamycin, 25-O-deacetyl-1,4-dideoxy-1,4-dihydro-25-O-(3-((1-methyl-3-piperidinyl)methoxy)-1,3-dioxopropyl)-3-(4-morpholinyl)-1,4-dioxo  *Rifamycins. J Antibiot (Tokyo) 1987;40(12):1733
benzothiazole-rifamycin  78768-62-4   *Rifamycins *Benzothiazoles. Yao Hsueh Hseuh Pao 1984;19(12):881
4-deoxy-3'-bromopyrido(1',2'-1,2)imidazo(5,4-c)rifamycin S  95360-35-3 2,7-(Epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-e)pyrido(1,2-a)benzimidazole-1,15(2H)-dione, 25-(acetyloxy)-12-bromo-5,6,21,23-tetrahydroxy-27-methoxy-2,4,16,20,22,24,26-heptamethyl-, (2S-(2R*,16Z,18E,20R*,21R*,22S*,23S*,24S*,25R*,26S*,27R*,28E))  *Rifamycins. J Antibiot (Tokyo) 1984;37(12):1623
rifaximin  88747-56-2   *Rifamycins.
Pharma Action Anti-Infective Agents ; Gastrointestinal Agents 		Boll Soc Ital Biol Sper 1984;60(5):1079XIFAXAN
FCE 22250  84475-07-0 Rifamycin, 3-(methyl(1-piperidinylmethylene)hydrazino)  *Rifamycins. G Ital Chemioter 1983;30(2-3):97
3-formylrifamycin SV  13292-22-3   *Rifamycins. Rev Infect Dis 1983;5 Suppl 3:S433
25-deacetoxy-25-hydroxyrifamycin S  17555-51-0   *Rifamycins. J Antibiot (Tokyo) 1983;36(5):516
R 761  57184-22-2 Rifamycin, 3-(4-(2-methylpropyl)-1-piperazinyl)  *Rifamycins. Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao 1982;4(5):293
rifamycin O  14487-05-9   *Rifamycins. FEBS Lett 1983;151(1):36
3-hydrazinorifamycin  0   *Rifamycins. J Antibiot (Tokyo) 1982;35(11):1621
rifamdin  89499-17-2 Rifamycin, 3-(((4-(2-methylpropyl)-1-piperazinyl)imino)methyl)  *Rifamycins. Chung Hua Chieh Ho Ho Hu Hsi Hsi Chi Ping Tsa Chih 1982;5(2):71
16,17-dihydrorifamycin S  51874-02-3 Rifamycin, 1,4-dideoxy-1,4,16,17-tetrahydro-1,4-dioxo  *Rifamycins. J Antibiot 1982;35(5):594
16,17-dihydro-17-hydroxyrifamycin S  82534-57-4 Rifamycin, 1,4-dideoxy-1,4,16,17-tetrahydro-17-hydroxy-1,4-dioxo  *Rifamycins. J Antibiot 1982;35(5):594
3-carbomethoxy rifamycin S  72393-97-6   *Rifamycins. Mol Pharmacol 1982;21(2):394
rifamycin L  26117-02-2 Rifamycin, 4-(hydroxyacetate)  *Rifamycins. J Antibiotics (Tokyo) 1982;35(1):74
rifamycin B  13929-35-6   *Rifamycins. J Antibiot (Tokyo) 1982;35(1):74
rifamycin S  13553-79-2   *Rifamycins. J Biochem 1982;91(1):381
rifamycin Verde  72428-95-6 Rifamycin verde  *Rifamycins. J Antibiot (Tokyo) 1980;33(8):842
rifamycin Q  59232-88-1 Rifamycin P, 2'-(hydroxymethyl)  *Rifamycins. J Antibiot (Tokyo) 1980;33(8):842
rifamycin P  59232-87-0   *Rifamycins. J Antibiot (Tokyo) 1980;33(8):842
rifamycin SV  6998-60-3 rifamycin  *Rifamycins.
Pharma Action Antirheumatic Agents 		J Int Med Res 1980;8(1):1
protorifamycin I  69239-55-0 Rifamycin W, 8-deoxy  *Rifamycins. J Antibiot (Tokyo) 31(11):1124;1978
rifazone-82  52474-42-7   *Rifamycins. J Virol 25(3):944;1978; Oncology 35:76;1978
tolypomycinone  22356-23-6 4-de((tetrahydro-6-hydroxy-2-methyl-2H-pyran-2- yl)imino)-4-oxotolypomycin Y  *Rifamycins. J Med Chem 20(10):1287;1977; Mol Pharmacol 14(4):693;1978
halomicins  0   *Rifamycins. J Antibiot (Tokyo) 30(7):625;1977
halomicin B  54356-09-1   *Rifamycins. J Org Chem 41(7):1258;1976
rifamide  2750-76-7   *Rifamycins.
C 27  37839-24-0 3-(4-(dicyclohexylmethyl)-1-piperidinyl)rifamycin  *Rifamycins. Biochem Biophys Res Commun 53(1):194;1973
AF 013  35225-13-9 3-(((octyloxy)imino)methyl)rifamycin  *Rifamycins. Biochem Biophys Res Commun 49(5):1263;1972; Biochem Biophys Res Commun 53(1):194;1973
tolypomycin Y  23412-26-2   *Rifamycins. Antibiotiki 24(7):545;1979; J Antibiot (Tokyo) 31(11):1195;1978

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