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tRNA Methyltransferases

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Definition: Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases within a transfer RNA molecule. EC 2.1.1.  DF: note short X ref    Other names T RNA Methyltransferases; RNA, Transfer, Methyltransferases; RNA Methylases; RNA Methyltransferases, T; Methyltransferases, tRNA; Methyltransferases, T RNA; Methylases, RNA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TRM10 protein, S cerevisiae  EC 2.1.1.-   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. RNA. 2003 May;9(5):574-85.
TRM9 protein, Arabidopsis  EC 2.1.1.-   *tRNA Methyltransferases *Arabidopsis Proteins. Nucleic Acids Res. 2011 Sep 1;39(17):7688-701
ALKBH8 protein, human  EC 2.1.1.-   *tRNA Methyltransferases. Mol Cell Biol 2010 May;30(10):2449-59
ALKBH8 protein, mouse  EC 2.1.1.-   *tRNA Methyltransferases DNA Repair. Mol Cell Biol 2010 Apr;30(7):1814-25
TYW4 protein, S cerevisiae  EC 2.1.1.-   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Nucleic Acids Res 2009 May;37(9):2910-25
Trm5 protein, S cerevisiae  EC 2.1.1.-   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. J Biol Chem 2007 Sep 21;282(38):27744-53
TRMT12 protein, human  EC 2.1.1.-   *tRNA Methyltransferases. Genes Chromosomes Cancer 2007 Jul;46(7):694-707
Tgs1 protein, S pombe  EC 2.1.1.-   *tRNA Methyltransferases *Schizosaccharomyces pombe Proteins. Nucleic Acids Res 2007;35(5):1411-20
TRM13 protein, S cerevisiae  EC 2.1.1.-   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. RNA 2007 Mar;13(3):404-13
TRMT1L protein, human  EC 2.1.1.-   *tRNA Methyltransferases. Genomics 2001 Apr 15;73(2):211-22
Trm1-like protein, mouse  EC 2.1.1.-   *tRNA Methyltransferases. Gene 2007 Mar 15;389(2):174-85
YfhQ protein, E coli  EC 2.1.1.-   *tRNA Methyltransferases. BMC Mol Biol 2006;7:23
Trm1-11, S cerevisiae  EC 2.1.1.-   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Genetics. 2005 Aug;170(4):1553-60
Trm112 protein, S cerevisiae  EC 2.1.1.32   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2005 Jun;25(11):4359-70
Trm11 protein, S cerevisiae  EC 2.1.1.32   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2005 Jun;25(11):4359-70
TRMU protein, human  EC 2.1.1.61   *tRNA Methyltransferases *Mitochondrial Proteins. J Biol Chem 2005 Jan 14;280(2):1613-24
SLM3 protein, S cerevisiae  EC 2.1.1.61   *tRNA Methyltransferases *Mitochondrial Proteins. J Biol Chem 2005 Jan 14;280(2):1613-24
TrmD protein, E coli  EC 2.1.1.-   *tRNA Methyltransferases *Escherichia coli Proteins. Biochemistry 2004 Jul 20;43(28):9243-55
TRMT5 protein, human  EC 2.1.1.31   *tRNA Methyltransferases. Biochemistry 2004 Jul 20;43(28):9243-55
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1, mouse  EC 2.1.1.61   *tRNA Methyltransferases. Biochim Biophys Acta 2004 Jan 20;1676(2);119-26
tRNA(cytosine-5)methyltransferase, mouse  EC 2.1.1.29   *tRNA Methyltransferases.
tRNA (cytosine-5)-methyltransferase, Xenopus  EC 2.1.1.29   *tRNA Methyltransferases *Xenopus Proteins.
tRNA m(5)C-methyltransferase, human  EC 2.1.1.29   *tRNA Methyltransferases.
TRM9 protein, S cerevisiae  EC 2.1.1.-   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Mol Cell Biol. 2003 Dec;23(24):9283-92
YggH protein, E coli  EC 2.1.1.-   *tRNA Methyltransferases *Escherichia coli Proteins. J Bacteriol 2003 May;185(10):3238-43
Trm7 protein, S cerevisiae  EC 2.1.1.-   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. EMBO J 2002 Apr 2;21(7):1811-20
Gcd10 protein, S cerevisiae  EC 2.1.1.-   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Genes Dev 1995 Jul 15;9(14):1781-96
GCD14 protein, S cerevisiae  EC 2.1.1.36   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1999 Jun;19(6):4167-81
N(2),N(2)-dimethylguanosine-26-methyltransferase  EC 2.1.1.-   *tRNA Methyltransferases. Biochemistry 1994 Aug 16;33(32):9546-51
TRM2 protein, S cerevisiae  EC 3.1.-   *Deoxyribonucleases *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Nucleic Acids Res 1992 Oct 11;20(19):5215-21
NOP2 protein, human  EC 2.1.1.-   *Nuclear Proteins *tRNA Methyltransferases. Cancer Commun 1989;1(1):29; Cancer Commun 1990;2(2):63
N(2),N(2)-dimethylguanosine-specific tRNA methyltransferase  EC 2.1.1.-   *tRNA Methyltransferases. Mol Cell Biol 1989;9(4):1611
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase  EC 2.1.1.61   *tRNA Methyltransferases. J Biol Chem 1987;262(18):8488
tRNA (guanine-N1-)-methyltransferase  EC 2.1.1.31   *tRNA Methyltransferases. J Biol Chem 1983;258(2):1343
tRNA (guanine-N7-)-methyltransferase  EC 2.1.1.33   *tRNA Methyltransferases. Arch Biochem Biophys 1982;219(1):149
tRNA (guanosine-2'-O-)-methyltransferase  EC 2.1.1.34   *tRNA Methyltransferases. J Biol Chem 1982;257(13):7388
tRNA(uridine-5-)-methyltransferase  EC 2.1.1.-   *tRNA Methyltransferases. J Biol Chem 1980;255(17):8296
NCL1 protein, S cerevisiae  EC 2.1.1.29   *tRNA Methyltransferases *Saccharomyces cerevisiae Proteins. Gene 1998 Oct 5;220(1-2):109-17; J Biol Chem 1980;255(10):4636
tRNA (guanine-N2-)-methyltransferase  EC 2.1.1.32   *tRNA Methyltransferases. Biochem Biophys Res Commun 81(2):315;1978; Biochemistry 18(23):5253;1979; Nature New Biol 246(153):135;1973
tRNA(adenine-1-)methyltransferase  EC 2.1.1.36   *tRNA Methyltransferases. J Biol Chem 252(14):4790;1977; J Neurochem 31:85;1978
tRNA(uracil-5)-methyltransferase  EC 2.1.1.35   *tRNA Methyltransferases. Enzyme 24(6):353;1979
RNA ribose methylase  EC 2.1.1.-   *tRNA Methyltransferases. Nucleic Acids Res 2(4):603;1975

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