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Spiperone

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Definition: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.     
Pharmacological Action Antipsychotic Agents; Dopamine Antagonists 		Other names Spiroperone; Spiroperidol
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
BODIPY N-(p-aminophenethyl)spiperone  0   *Boron Compounds Spiperone/*analogs & derivatives. J Neurochem 1995 Aug;65(2):691-703
rhodamine-N-(p-aminophenethyl)spiperone  0   *Rhodamines Spiperone/*analogs & derivatives. J Neurochem 1995 Aug;65(2):691-703
N-(4-nitrobenzyl)spiperone  138091-80-2   *Nitrobenzenes Spiperone/*analogs & derivatives Fluorine Radioisotopes Ligands. Nucl Med Biol 1993 Apr;20(3):269-78
N-(4-isothiocyanatophenethyl)spiperone  135261-88-0   Spiperone/*analogs & derivatives. J Pharmacol Exp Ther 1991;257(2):608
iodoethylspiperone  130482-21-2   Spiperone/*analogs & derivatives Iodine Radioisotopes. Int J Rad Appl Instrum (B) 1990;17(4):389
N-(iodoallyl)spiperone  124654-22-4   Spiperone/*analogs & derivatives. Life Sci 1990;46(26):1967
3-(2-aminoethyl)-8-(3-(4-fluorobenzoyl)propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one  125094-03-3   Spiperone/*analogs & derivatives. Biochem Biophys Acta 1989;986(2):271
technetium Tc 99m spiperone dithiocarbamate  0   *Organotechnetium Compounds Spiperone/*analogs & derivatives. Int J Rad Appl Instrum (A) 1989;40(6):485
4-aminospiroperidol  114442-96-5   Spiperone/*analogs & derivatives. J Neurochem 1988;50(4):1253
azido-N-(4-aminophenethyl)spiperone  118797-70-9   Spiperone/*analogs & derivatives. J Neurochem 1987;49(5):1644
2'-iodospiperone  103445-60-9   Spiperone/*analogs & derivatives Iodine Radioisotopes. Life Sci 1987;41(17):1989
N-(3-fluoropropyl)spiroperidol  106114-44-7   Spiperone/*analogs & derivatives. J Nucl Med 1987;28(7):1164
3-N-(2-fluoroethyl)spiperone  106114-42-5   Spiperone/*analogs & derivatives Fluorine Radioisotopes.
Pharma Action Radiopharmaceuticals 		Life Sci 1987;40(1):81
4-azido-N-methylspiperone  104820-55-5   Spiperone/*analogs & derivatives. Eur J Pharmacol 1986;127(3):297
((carboxymethylene)oximino)spiperone-sepharose 4B  100019-61-2   Spiperone/*analogs & derivatives. Biochemistry 1986;25(4):749
N-(4-azido-3-iodophenethyl)spiperone  95754-28-2 1,3,8-Triazaspiro(4.5)decan-4-one, 3-(2-(4-azido-3-(iodo-125I)phenyl)ethyl)-8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl-, (6R-(3(1S*,2R*),6alpha,7beta(R*)))  *Azides Spiperone/*analogs & derivatives. J Biol Chem 1985;260(4):1983
N-(4-aminophenethyl)spiroperidol  93801-18-4 1,3,8-Triazaspiro(4.5)decan-4-one, 3-(2-(4-aminophenyl)ethyl)-8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl-, (5Z,11alpha,13E,15R)  Spiperone/*analogs & derivatives. FEBS LETT 1984;176(2):436
4-iodospiperone  85562-22-7   Spiperone/*analogs & derivatives. Life Sci 1984;35(19):1981
3-N-methylspiperone  87539-19-3 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4-(4-fluorophenyl)-4-oxobutyl)-3-methyl-1-phenyl  Spiperone/*analogs & derivatives Fluorine Radioisotopes.
Pharma Action Dopamine Agonists 		Science 1983;221(4617):1264
spiroperidol receptor  0   *Receptors, Dopamine Spiperone. Eur J Pharmacol 1981;72(1):121
4-bromospiperone  76139-30-5 1,3,8-Triazaspiro(4.5)decan-4-one, 1-(4-bromophenyl)-8-(4-(4-fluorophenyl)-4-oxobutyl)  Spiperone/*analogs & derivatives. J Pharm Sci 1980;69(8):984

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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