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Succinate Dehydrogenase

More information in Books or onNLM PubMed
Definition: A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.      Other names Succinic Oxidase; Reductase, Fumarate; Dehydrogenase, Succinic; Dehydrogenase, Succinate; Oxidase, Succinic; Succinic Dehydrogenase; Fumarate Reductase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SDH2 protein, S cerevisiae  0   *Succinate Dehydrogenase *Saccharomyces cerevisiae Proteins Iron-Sulfur Proteins Protein Subunits. Hum Mol Genet 2009 May 15;18(10):1860-8
SDH1 protein, S cerevisiae  EC 1.3.99.1   *Succinate Dehydrogenase *Saccharomyces cerevisiae Proteins Flavoproteins Protein Subunits. FEBS J 2008 Mar;275(6):1103-17
amicarthiazol  0   *Anilides *Thiazoles Succinate Dehydrogenase/antagonists & inhibitors. Pest Manag Sci 2006 May;62(5):440-5
MEV-1 protein, C elegans  EC 1.3.99.1   *Succinate Dehydrogenase *Caenorhabditis elegans Proteins Protein Subunits. FASEB J 2006 Jan;20(1):172-4
FRDm1 protein, Trypanosoma brucei  EC 1.3.99.1   *Succinate Dehydrogenase *Protozoan Proteins Mitochondrial Proteins. J Biol Chem 2005 Apr 29;280(17):16559-70
SDH2-3 protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins Succinate Dehydrogenase Protein Subunits. Plant Mol Biol 2001 May;46(2):241-50
SDH2-2 protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins Succinate Dehydrogenase Protein Subunits. Plant Mol Biol 2001 May;46(2):241-50
SDH2-1 protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins Succinate Dehydrogenase Protein Subunits. Plant Mol Biol 2001 May;46(2):241-50
SDHD protein, human  0   *Succinate Dehydrogenase.
SdhC protein, bacteria  0   *Bacterial Proteins Succinate Dehydrogenase.
cyt-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Cytochromes b Succinate Dehydrogenase. Free Radic Biol Med 2002 Oct 15;33(8):1021-5
stolonoxide C methyl ester  0   *Dioxolanes *Furans Succinate Dehydrogenase/antagonists & inhibitors. J Med Chem 2001 Jul 5;44(14):2362-5
theonyltrifluoroacetone  0   *Thiophenes Acetone/*analogs & derivatives Succinate Dehydrogenase/antagonists & inhibitors. Blood 2001 Jun 1;97(11):3544-51
succinic tetrazolium reductase  EC 1.-   *Succinate Dehydrogenase. Pigment Cell Res 1999 Aug;12(4):237-45
SDH4 protein, Arabidopsis  0   *Membrane Proteins *Arabidopsis Proteins Succinate Dehydrogenase. Curr Genet 1998 Oct;34(4):313-7
flavocytochrome c3  EC 1.3.99.-   *Cytochrome c Group *Succinate Dehydrogenase. Microbiology 1998 Apr;144( Pt 4):937-45
SdhD protein, archaeal  0   *Membrane Proteins *Archaeal Proteins Succinate Dehydrogenase. J Bacteriol 1997 Sep;179(17):5560-9
SDHB protein, human  EC 1.3.5.1   *Succinate Dehydrogenase. J Bacteriol 1997 Sep;179(17):5560-9
SdhA protein, Bacteria  0   *Bacterial Proteins *Flavoproteins Succinate Dehydrogenase. Gene 1993 Oct 29;133(1):135-40
OSM1 protein, S cerevisiae  EC 1.3.99.1   *Succinate Dehydrogenase *Saccharomyces cerevisiae Proteins. Gene 1990;87(2):157
succinate-ferricyanide oxidoreductase  EC 1.3.99.-   *Succinate Dehydrogenase. Dokl Akad Nauk SSR 1983;273(1):242
fumarate reductase complex  EC 1.3.99.-   *Succinate Dehydrogenase. Eur J Biochem 1981;120(3):577
H(2) fumarate reductase  EC 1.-   *Hydrogenase *Succinate Dehydrogenase. Biochim Biophys Acta 267(3):479;1972
3-nitropropionic acid  504-88-1   *Nitro Compounds *Propionic Acids Fabaceae Neurotoxins Succinate Dehydrogenase/antagonists & inhibitors.
Pharma Action Antihypertensive Agents ; Convulsants 		Am J Vet Res 1980;41(3):377; J Biol Chem 254(12):5161;1979; Proc Natl Acad Sci USA 74(9):3767;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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