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Factor IXa

More information in Books or onNLM PubMed
Definition: Activated form of factor IX. This activation can take place via the intrinsic pathway by the action of factor XIa and calcium, or via the extrinsic pathway by the action of factor VIIa, thromboplastin, and calcium. Factor IXa serves to activate factor X to Xa by cleaving the arginyl-leucine peptide bond in factor X.  /defic   
See Also Coagulants 		Other names Factor IX, Activated; Coagulation Factor IXa; IXa, Coagulation Factor; Factor IXa, Coagulation; Activated Factor IX; Blood Coagulation Factor IX, Activated
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RB 006  0   *Aptamers, Nucleotide Factor IXa/antagonists & inhibitors. Circulation 2006 Dec 5;114(23):2490-7
5-dimethylaminonaphthalene-1-sulfonyl glutamyl-glycyl-arginyl chloromethyl ketone inactivated factor IXa  0   *Factor IXa. J Biol Chem 2000 Apr 28;275(17):13071-81
cancer procoagulant  EC 3.4.22.26   *Cysteine Endopeptidases *Neoplasm Proteins Blood Coagulation Factors Neoplasm Proteins Factor VIIIa Factor IXa. J Clin Invest 1981;67(6):1665; JNCI 62(4):772;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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