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Receptors, Lymphocyte Homing

More information in Books or onNLM PubMed
Definition: Cell surface glycoproteins on lymphocytes and other leukocytes that mediate adhesion to specialized blood vessels called high endothelial venules. Several different classes of lymphocyte homing receptors have been identified, and they appear to target different surface molecules (addressins) on high endothelial venules in different tissues. The adhesion plays a crucial role in the trafficking of lymphocytes.  DF: RECEPT LYMPHOCYTE HOMING   
Examples Antigens, CD44; Integrin alpha4beta1; Lymphocyte Function-Associated Antigen-1; L-Selectin 		Other names Lymphocyte Homing Receptors; Homing Receptors, T-Cell; Hermes Antigen Family; T-Cell Homing Receptors; Receptors, T-Cell Homing; Homing Receptors, T Cell; Homing Receptors, Lymphocyte; Antigen Family, Hermes; Receptor, Lymph Node Homing; Lymph Node Homing Receptor; Homing Receptor, Lymph Node
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
STAB1 protein, human  0   *Cell Adhesion Molecules, Neuronal *Receptors, Lymphocyte Homing. Biochem J 2002 Feb 15;362(Pt 1):155-64
L-selectin counter-receptors  0   *Antigens, Surface *Membrane Proteins Receptors, Lymphocyte Homing. J Cell Biol 1991;114(2):343
CTAGE1 protein, human  0   *Antigens, Differentiation, T-Lymphocyte *Membrane Glycoproteins Tumor Markers, Biological Receptors, Lymphocyte Homing. J Invest Dermatol 1990;94(4):252

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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