encyclopedia of medical concepts
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Siderophores
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Definition
: Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994)
Other names
Siderochromes
Substances having this pharmacologic action:
mycobactins
;
pyochelin
;
aerobactin
;
pseudobactin
;
siderophore receptors
;
vibriobactin
;
pyoverdin
;
Enterobactin
;
Deferoxamine
;
yersiniabactin
;
FpvA protein, Pseudomonas aeruginosa
;
anguibactin
;
desferrithiocin
Substance
CAS Registry & name
Categories
Source
Drugs
*
trivanchrobactin
0
*Peptides
Siderophores.
J Nat Prod. 2010 Jun 25;73(6):1038-43
vanchrobactin
0
*Peptides
Siderophores.
Org Biomol Chem 2008 Apr 7;6(7):1278-87
ceuE protein, Campylobacter coli
0
*Bacterial Proteins
*Carrier Proteins
Campylobacter coli
Siderophores.
pseudoalterobactin B
0
*Biological Factors
Siderophores.
J Antibiot (Tokyo) 2003 Oct;56(10);871-5
pseudoalterobactin A
0
*Biological Factors
Siderophores.
J Antibiot (Tokyo) 2003 Oct;56(10);871-5
asterobactin
0
*Biological Factors
Siderophores.
J Antibiot (Tokyo) 2002 Jun;55(6):593-7
petrobactin
0
*Benzamides
Siderophores.
J Am Chem Soc 2002 Jan 23;124(3):378-9
pyridinochelin
0
*Catechols
Siderophores.
Z Naturforsch [C] 2001 Jul-Aug;56(7-8):540-6
ceuE protein, Campylobacter jejuni
0
*Bacterial Proteins
*Carrier Proteins
Campylobacter jejuni
Siderophores.
Diag Microbiol Infect Dis 2001 May-Jun;40(1-2):11-9
pseudomonine
0
*Benzamides
Siderophores.
J Bacteriol 2001 Mar;183(6):1909-20
anachelin
0
*Quinolinium Compounds
Siderophores.
Z Naturforsch (C) 2000 Sep-Oct;55(9-10):681-7
coelichelin
0
*Oligopeptides
Siderophores
Peptide Biosynthesis, Nucleic Acid-Independent.
FEMS Microbiol Lett 2000 Jun 15;187(2):111-4
coprogen B
0
*Hydroxamic Acids
Siderophores.
Infect Immun 2000 Apr;68(4):2338-43
quinolobactin
0
*Quinolines
Siderophores.
Appl Environ Microbiol 2000 Feb;66(2):487-92
rpoI protein, Rhizobium leguminosarum
0
*Bacterial Proteins
*Sigma Factor
Rhizobium leguminosarum
Siderophores.
Mol Plant Microbe Interact 1999 Nov;12(11):994-9
FR 160
0
Spermidine/*analogs & derivatives
Siderophores.
Antimicrob Agents Chemother 1997 Aug;41(8):1837-9
6-
alanineferrirubin
0
*Ferric Compounds
*Peptides, Cyclic
Siderophores.
Acta Crystallogr C 1997 Jun 15;53( Pt 6):716-8
isopyoverdin
0
*Oligopeptides
Pigments, Biological
Siderophores.
Z Naturforsch (C) 1995 Sep-Oct;50(9-10):622-9
acinetobactin
160472-93-5 4-
Oxazolecarboxamide, 2-
(2,3-
dihydroxyphenyl)-
4,5-
dihydro-
N-
hydroxy-
N-
02-
(1H-
imidazol-
4-
yl)ethyl)-
5-
methyl-
, cis-
(-
)
*Imidazoles
*Oxazoles
Acinetobacter
Siderophores.
Arch Microbiol 1994;162(4):249-54
vibrioferrin
157568-17-7 1,2,3-
Propanetricarboxylic acid, 2-
hydroxy-
, 1-
02-
002-
(2-
carboxy-
2-
hydroxy-
5-
oxo-
1-
pyrrolidinyl)-
1-
oxopropyl)amino)ethyl) ester
*Citrates
*Pyrrolidinones
Siderophores.
J Biochem (Tokyo) 1994 May;115(5):868-74
rhizoferrin
138846-62-5 Butanedioic acid, 2,2'-
(1,4-
butanediylbis(imino(2-
oxo-
2,1-
ethanediyl)))bis(2-
hydroxy)
*Ferric Compounds
Siderophores.
Biochem Pharmacol 1994 May 18;47(10):1843-50
acinetoferrin
0
*Citrates
*Hydroxamic Acids
Siderophores.
Biometals 1994 Apr;7(2):170-6
vulnibactin
156368-88-6 4-
Oxazolecarboxamide, N-
(3-
(((4,5-
dihydro-
2-
(2-
hydroxyphenyl)-
5-
methyl-
4-
oxazolyl)carbonyl)amino)propyl)-
N-
(3-
((2,3-
dihydroxybenzoyl)amino)propyl)-
4,5-
dihydro-
2-
(2-
hydroxyphenyl)-
5-
methyl-
, (4S-
(4alpha(4R*,5S*),5beta))
*Amides
*Oxazoles
Siderophores.
Biometals 1994 Apr;7(2):109-16
pyoverdin GM-
II
0
*Oligopeptides
Pigments, Biological
Siderophores.
Biochemistry 1994 Mar 15;33(10):2843-51
alterobactin B
153888-53-0
*Oligopeptides
Siderophores.
Nature 1993 Dec 2;366(6454):455-8
alterobactin A
153888-52-9
*Peptides, Cyclic
Siderophores.
Nature 1993 Dec 2;366(6454):455-8
urbs1 protein, Ustilago maydis
0
*Fungal Proteins
*Transcription Factors
Ustilago
Siderophores.
Mol Cell Biol 1993 Nov;13(11):7091-7100
staphyloferrin B
127689-48-9 Staphyloferrin B
*Citrates
Staphylococcus
Siderophores.
Biometals 1993 Autumn;6(3):185-92
N(1),N(7)-
bis(2,3-
dihydroxybenzoyl)norspermidine
88381-35-5
*Catechols
Spermidine/*analogs & derivatives
Siderophores.
J Biochem (Tokyo) 1993 May;113(5):538-44
fluvibactin
103185-30-4 4-
Oxazolecarboxamide, N,N-
bis(3-
((2,3-
dihydroxybenzoyl)amino)propyl)-
2-
(2,3-
dihydroxyphenyl)-
4,5-
dihydro-
5-
methyl-
, (4S-
trans)
*Catechols
Spermidine/*analogs & derivatives
Siderophores.
J Biochem (Tokyo) 1993 May;113(5):538-44
JAM 2-
263
134782-23-3
*Catechols
*Lactams
Siderophores.
Antimicrob Agents Chemother 1992 Oct;36(10):2166-75
nannochelin C
133705-26-7 L-
Lysine, N2,N2'-
(3-
carboxy-
3-
hydroxy-
1,5-
dioxo-
1,5-
pentanediyl)bis(N6-
hydroxy-
N6-
(1-
oxo-
3-
phenyl-
2-
propenyl)
*Citrates
*Hydroxamic Acids
Siderophores.
J Antibiot (Tokyo) 1992 Feb;45(2):147-50
nannochelin B
133705-27-8 L-
Lysine, N2-
(3-
carboxy-
5-
((1-
carboxy-
5-
(hydroxy(1-
oxo-
3-
phenyl-
2-
propenyl)amino)pentyl)amino)-
3-
hydroxy-
1,5-
dioxopentyl)-
N6-
hydroxy-
N6-
(1-
oxo-
3-
phenyl-
2-
propenyl)-
, 1-
methyl ester
*Citrates
*Hydroxamic Acids
Siderophores.
J Antibiot (Tokyo) 1992 Feb;45(2):147-50
nannochelin A
133705-25-6 L-
Lysine, N2,N2'-
(3-
carboxy-
3-
hydroxy-
1,5-
dioxo-
1,5-
pentanediyl)bis(N6-
hydroxy-
N6-
(1-
oxo-
3-
phenyl-
2-
propenyl)-
, 1,1'-
dimethyl ester
*Citrates
*Hydroxamic Acids
Siderophores.
J Antibiot (Tokyo) 1992 Feb;45(2):147-50
azurechelin
0
*Salicylic Acids
Siderophores.
J Gen Microbiol. 1993 Sep;139 ( Pt 9):1995-2001; J Med Microbiol 1992 Mar;36(3):184-9
7-
((N(5)acetyl-
N(5)-
hydroxyornithyl-
N(5)acetyl-
N(5)hydroxyornithyl-
N(5)-
acetyl-
N(5)-
hydroxyornithyl-
4-
hydroxyphenylglycyl)amino)-
3-
chloro-
1-
carba-
3-
cephem-
4-
carboxylic acid
124620-50-4
*Lactams
Siderophores.
J Med Chem 1991;34(3):968
7-
((N(5)-
acetyl-
N(5)-
hydroxyornithyl-
N(5)-
acetyl-
N(5)-
hydroxyornithyl-
N(5)-
acetyl-
N(5)-
hydroxyornithyl-
phenylglycyl)amino)-
1-
carba-
3-
chloro-
3-
cephem-
4-
carboxylic acid
124650-78-8
*Lactams
Siderophores.
J Med Chem 1991;34(3):968
hydroxyneocoprogen I
135500-10-6
*Hydroxamic Acids
Siderophores.
Biol Met 1990;2(1):11
hydroxyisoneocoprogen I
135500-11-7
*Hydroxamic Acids
Siderophores.
Biol Met 1990;2(1):11
hydroxycoprogen
135467-86-6
*Hydroxamic Acids
Siderophores.
Biol Met 1990;2(1):11
pseudobactin 589 A
0
*Peptides, Cyclic
Siderophores.
Biochemistry 1990;29(31):7348
N(alpha)-
dimethylisoneocoprogen I
117852-96-7
*Hydroxamic Acids
Siderophores.
Biol Met 1988;1(1):4
N(alpha)-
dimethylneocoprogen
117852-95-6
*Hydroxamic Acids
Siderophores.
Biol Met 1988;1(1):4
N(alpha)-
dimethylcoprogen
117892-97-4
*Hydroxamic Acids
Siderophores.
Biol Met 1988;1(1):4
amonabactin P
120919-03-1
*Oligopeptides
Siderophores.
Biol Met 1989;2(3):155
amonabactin T
120919-04-2
*Oligopeptides
Siderophores.
Biol Met 1989;2(3):155
staphyloferrin A
127902-98-1 Butanedioic acid, 2,2'-
((1-
carboxy-
1,4-
butanediyl)bis(imino(2-
oxo-
2,1-
ethanediyl)))bis(2-
hydroxy)
*Citrates
Ornithine/*analogs & derivatives
Siderophores.
FEMS Microbiol Lett 1990;55(1-2):201
myxochelin A
120243-02-9 Benzamide, N,N'-
(1-
(hydroxymethyl)-
1,5-
pentanediyl)bis(2,3-
dihydroxy)
Lysine/*analogs & derivatives
Siderophores.
J Antibiot (Tokyo) 1989;42(1):14
chrysobactin
120124-51-8 L-
Serine, N-
(N2-
(2,3-
dihydroxybenzoyl)-
D-
lysyl)