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Annexins

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Definition: Family of calcium- and phospholipid-binding proteins which are structurally related and exhibit immunological cross-reactivity. Each member contains four homologous 70-kDa repeats. The annexins are differentially distributed in vertebrate tissues (and lower eukaryotes) and appear to be involved in MEMBRANE FUSION and SIGNAL TRANSDUCTION.     
Examples Annexin A1; Annexin A2; Annexin A3; Annexin A4; Annexin A5; Annexin A6; Annexin A7 		Other names Lipocortins; Calpactins; Calelectrins; Calcimedins; Annexin XI; Annexin X; Annexin VIII; Annexin IX; Annexin B9; Annexin B10; Annexin A8; Annexin A11; Lipocortin; Chromobindins; Calpactin; Calelectrin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tat-ANX1 fusion protein  0   *Recombinant Fusion Proteins *Gene Products, tat *Annexins. Biochem Biophys Res Commun. 2012 Jan 20;417(3):1024-9.
technetium 99m HYNIC-annexin B1  0   *Organotechnetium Compounds *Annexins. Apoptosis 2008 Apr;13(4):600-8
Nex-4 protein, C elegans  0   *Annexins *Caenorhabditis elegans Proteins. J Biochem (Tokyo) 2007 Jan;141(1):47-55
Nex-3 protein, C elegans  0   *Annexins *Caenorhabditis elegans Proteins. J Cell Sci 1999 Jun;112( Pt 12):1901-13
Nex-2 protein, C elegans  0   *Annexins *Caenorhabditis elegans Proteins. J Cell Sci 1999 Jun;112( Pt 12):1901-13
Cy5.5-annexin V conjugate  0   *Carbocyanines *Annexins. Cancer Res 2003 Apr 15;63(8):1936-42
technetium 99m annexin B1  0   *Organotechnetium Compounds *Annexins Ligands. Biochem Biophys Res Commun 2005 Oct 7;335(4):1102-6
annexin 1, Arabidopsis  EC 1.11.1-   *Annexins *Arabidopsis Proteins Peroxidases. Biochem Biophys Res Commun 2005 Oct 28;336(3):868-75
Anxa9 protein, mouse  0   *Annexins. Biochim Biophys Acta 2004 Dec 6;1742(1-3):141-9
ANXB12 protein, Hydra attenuata  0   *Annexins. Biophys J 2004 Jan;86(1 Pt 1):145-51
Anxa10 protein, mouse  0   *Annexins.
liver annexin like-1 protein, rat  0   *Annexins. Genes Cells 2002 Nov;7(11):1183-90
annexin E1 protein, Giardia lamblia  0   *Protozoan Proteins *Annexins. J Biol Chem 2002 Jul 12;277(28):25703-6
annexin B1, Taenia solium  0   *Helminth Proteins *Annexins. Mol Biochem Parasitol 2002 Jan;119(1):1-5
ANXA10 protein, human  0   *Annexins. Genomics 1999 Aug 15;60(1):40-9
ANXA9 protein, human  0   *Annexins. FEBS Lett 1998 Sep 4;434(3):300-4
AnnMs2 protein, Medicago sativa  0   *Plant Proteins *Annexins. Plant J 1998 Jul;15(2):185-97
Ann1 protein, Medicago truncatula  0   *Plant Proteins *Annexins. Mol Plant Microbe Interact 1998 Jun;11(6):504-13
Nex-1 protein, C elegans  0   *Annexins *Caenorhabditis elegans Proteins. J Cell Biol 1996 Mar;132(6):1079-92
calcyclin-associated protein 50  148412-77-5   *Annexins. J Biol Chem 1992 May 5;267(13):8919-24
vasocortin  0   *Annexins. Br J Pharmacol 1987;90(3):443
lipomodulin  0   *Annexins Glycoproteins Lymphokines Phospholipases A/antagonists & inhibitors.
Pharma Action Phosphodiesterase Inhibitors 		Proc Natl Acad Sci USA 1981;78(5):3199

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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