Definition: A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl diphosphate or geranylgeranyl diphosphate, are derived from the same biochemical pathway that produces cholesterol.
Other names Protein Isoprenylation; Post-Translational Isoprenylation; Prenylation, Protein; Polyisoprenylation, Protein; Geranylgeranylation, Protein; Farnesylation, Protein; Protein Polyisoprenylation; Protein Geranylgeranylation; Protein Farnesylation