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Spliceosomes

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Definition: Organelles in which the splicing and excision reactions that remove introns from precursor messenger RNA molecules occur. One component of a spliceosome is five small nuclear RNA molecules (U1, U2, U4, U5, U6) that, working in conjunction with proteins, help to fold pieces of RNA into the right shapes and later splice them into the message.  organelles in which splicing of mRNA occurs; A 11 qualif except /cytol; /genet permitted   
See Also RNA Splicing 		Other names Spliceosome
 
SubstanceCAS Registry & nameCategoriesSource
CEF1 protein, S cerevisiae  0   *RNA-Binding Proteins *Saccharomyces cerevisiae Proteins Spliceosomes.
Sfrs2 protein, mouse  0   *Nuclear Proteins *Ribonucleoproteins RNA Splicing Spliceosomes.
RNPC3 protein, human  0   *Nuclear Proteins *RNA-Binding Proteins Spliceosomes. Biochem Genet 2003 Oct;41(9-10):315-23
prp10 protein, S pombe  0   *Phosphoproteins *Ribonucleoprotein, U2 Small Nuclear *Schizosaccharomyces pombe Proteins Spliceosomes.
Sf3b1 protein, mouse  0   *Phosphoproteins *Ribonucleoprotein, U2 Small Nuclear Spliceosomes.
PRP31 protein, S cerevisiae  0   *Spliceosomes *Saccharomyces cerevisiae Proteins RNA Splicing.
CRNKL1 protein, human  0   *Nuclear Proteins Spliceosomes. Biochim Biophys Acta 2001 Feb 16;1517(3):449-54
Syf1 protein, S cerevisiae  0   *Spliceosomes *Cell Cycle Proteins *Saccharomyces cerevisiae Proteins. Genetics 2000 Dec;156(4):1503-17
IVNS1ABP protein, human  0   *Nuclear Proteins *Transcription Factors Spliceosomes. J Virol 1998 Sep;72(9):7170-80
SF3B1 protein, human  0   *Phosphoproteins *Ribonucleoprotein, U2 Small Nuclear Spliceosomes. Genes Dev 1998 May 15;12(10):1409-14
SNT309 protein, S cerevisiae  0   *Spliceosomes *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1998 Apr;18(4):2196-204
RSp31 protein, Arabidopsis  0   *RNA-Binding Proteins *Arabidopsis Proteins RNA Splicing Spliceosomes. Plant Cell 1996 Dec;8(12):2255-64
PRP19 protein, S cerevisiae  0   *Spliceosomes *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1993 Mar;13(3):1876-82
SRSF2 protein, human  147153-65-9   *Nuclear Proteins *Ribonucleoproteins RNA Splicing Spliceosomes. Proc Natl Acad Sci U S A 1992 Mar 1;89(5):1725-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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