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Mitogen-Activated Protein Kinase 10

More information in Books or onNLM PubMed
Definition: A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING.      Other names c jun N Terminal Kinase 3; c jun Kinase 3; Stress Activated Protein Kinase JNK3; Mitogen Activated Protein Kinase 10; MAPK10 Mitogen Activated Protein Kinase; Kinase 3, c-jun; 3F12 Kinase, p49; p54-SAPK(beta); p49(3F12) SAP Kinase; p49 3F12 Kinase; c-jun N-Terminal Kinase 3; c-jun Kinase 3; Stress-Activated Protein Kinase JNK3; Mitogen Activated Protein Kinase p49(3F12); MAPK10 Mitogen-Activated Protein Kinase; MAP Kinase p49(3F12); JNK3 Mitogen Activated Protein Kinase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1,3-benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile  0   *Acetonitriles *Benzothiazoles Mitogen-Activated Protein Kinase 8/antagonists & inhibitors Mitogen-Activated Protein Kinase 9/antagonists & inhibitors Mitogen-Activated Protein Kinase 10/antagonists & inhibitors. J Pharmacol Exp Ther 2004 Jul;310(1):25-32

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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