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Toll-Like Receptors

More information in Books or onNLM PubMed
Definition: A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.  general; prefer specifics   
Examples Toll-Like Receptor 1; Toll-Like Receptor 2; Toll-Like Receptor 3; Toll-Like Receptor 4; Toll-Like Receptor 5; Toll-Like Receptor 6; Toll-Like Receptor 7; Toll-Like Receptor 8; Toll-Like Receptor 9; Toll-Like Receptor 10 		Other names Toll Like Receptors; Toll Like Receptor; Receptors, Toll Like; Receptor, Toll-Like; Toll-Like Receptor; Receptors, Toll-Like
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Toll-9 protein, Drosophila  0   *Drosophila Proteins *Toll-Like Receptors. PLoS One 2011;6(2):e17470
gardiquimod  0   *Aminoquinolines *Imidazoles Toll-Like Receptors/agonists. Mol Immunol 2008 Jun;45(11):3238-43
Tlr13 protein, mouse  0   *Toll-Like Receptors. J Neuroinflammation 2008;5:53
Tlr12 protein, mouse  0   *Toll-Like Receptors. J Neuroinflammation 2008;5:53
Tlr11 protein, mouse  0   *Toll-Like Receptors. Science 2004 Mar 5;303(5663):1522-6
TLR11 protein, human  0   *Toll-Like Receptors. Science 2004 Mar 5;303(5663):1522-6
Tl protein, Drosophila  0   *Drosophila Proteins *Toll-Like Receptors. Genes Dev 1991;5(5):797

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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