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Toll-Like Receptor 7

More information in Books or onNLM PubMed
Definition: A pattern recognition receptor that binds several forms of imidazo-quinoline including the antiviral compound Imiquimod.      Other names Toll Like Receptor 7; Receptor, TLR7; TLR7 Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(2-methylpropyl)-1H-imidazo(4,5-c)quinolin 4-amine  0   *Quinolines Toll-Like Receptor 7/agonists. Antimicrob Agents Chemother. 1989 Sep;33(9):1511-5
N-(4-(4-amino-2-ethyl-1H-imidazo(4,5-c)quinolin-1-yl)butyl)methanesulfonamide  0   *Aminoquinolines *Sulfonamides Toll-Like Receptor 7/agonists. Cancer Immunol Immunother 2010 Dec;59(12):1877-84
CL 075  0   *Quinolines *Thiazoles Toll-Like Receptor 7/agonists Toll-Like Receptor 8/agonists. J Immunol 2010 Jul 1;185(1):738-47
CL097 compound  0   *Imidazoles *Quinolines Toll-Like Receptor 7/agonists Toll-Like Receptor 8/agonists. Shock 2009 Nov;32(5):484-90
IRS 954  0   *DNA Toll-Like Receptor 7/antagonists & inhibitors Toll-Like Receptor 9/antagonists & inhibitors. Eur J Immunol 2007 Dec;37(12):3582-6
3M 001  0   *Imidazoles *Quinolines Toll-Like Receptor 7/agonists. Int Immunol 2006 Jul;18(7):1115-26
N-(4-(4-amino-2-ethyl-1H-imidazo(4,5c)quinolin-1-yl)butyl)methanesulfonamide  0   *Quinolines *Sulfonamides Toll-Like Receptor 7/agonists. J Clin Pharmacol. 2007 Aug;47(8):962-9
S 28690  0   *Imidazoles *Quinolines Toll-Like Receptor 7/agonists. Leukemia 2006 Feb;20(2):286-95
TLR7 protein, human  0   *Toll-Like Receptor 7.
TLR7 protein, rat  0   *Toll-Like Receptor 7. J Immunol 2004 Jun 15;172(12):7485-94
Tlr7 protein, mouse  0   *Membrane Glycoproteins *Toll-Like Receptor 7. Am J Pathol. 2003 Aug;163(2):711-21
R 848  0   *Imidazoles Toll-Like Receptor 7/agonists Toll-Like Receptor 8/agonists. Cell Immunol 1999 Oct 10;197(1):62-72

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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