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Toll-Like Receptor 7
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Definition
: A pattern recognition receptor that binds several forms of imidazo-quinoline including the antiviral compound Imiquimod.
Other names
Toll Like Receptor 7; Receptor, TLR7; TLR7 Receptor
Substance
CAS Registry & name
Categories
Source
Drugs
*
1-
(2-
methylpropyl)-
1H-
imidazo(4,5-
c)quinolin 4-
amine
0
*Quinolines
Toll-Like Receptor 7/agonists.
Antimicrob Agents Chemother. 1989 Sep;33(9):1511-5
N-
(4-
(4-
amino-
2-
ethyl-
1H-
imidazo(4,5-
c)quinolin-
1-
yl)butyl)methanesulfonamide
0
*Aminoquinolines
*Sulfonamides
Toll-Like Receptor 7/agonists.
Cancer Immunol Immunother 2010 Dec;59(12):1877-84
CL 075
0
*Quinolines
*Thiazoles
Toll-Like Receptor 7/agonists
Toll-Like Receptor 8/agonists.
J Immunol 2010 Jul 1;185(1):738-47
CL097 compound
0
*Imidazoles
*Quinolines
Toll-Like Receptor 7/agonists
Toll-Like Receptor 8/agonists.
Shock 2009 Nov;32(5):484-90
IRS 954
0
*DNA
Toll-Like Receptor 7/antagonists & inhibitors
Toll-Like Receptor 9/antagonists & inhibitors.
Eur J Immunol 2007 Dec;37(12):3582-6
3M 001
0
*Imidazoles
*Quinolines
Toll-Like Receptor 7/agonists.
Int Immunol 2006 Jul;18(7):1115-26
N-
(4-
(4-
amino-
2-
ethyl-
1H-
imidazo(4,5c)quinolin-
1-
yl)butyl)methanesulfonamide
0
*Quinolines
*Sulfonamides
Toll-Like Receptor 7/agonists.
J Clin Pharmacol. 2007 Aug;47(8):962-9
S 28690
0
*Imidazoles
*Quinolines
Toll-Like Receptor 7/agonists.
Leukemia 2006 Feb;20(2):286-95
TLR7 protein, human
0
*Toll-Like Receptor 7.
TLR7 protein, rat
0
*Toll-Like Receptor 7.
J Immunol 2004 Jun 15;172(12):7485-94
Tlr7 protein, mouse
0
*Membrane Glycoproteins
*Toll-Like Receptor 7.
Am J Pathol. 2003 Aug;163(2):711-21
R 848
0
*Imidazoles
Toll-Like Receptor 7/agonists
Toll-Like Receptor 8/agonists.
Cell Immunol 1999 Oct 10;197(1):62-72