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DNA

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Definition: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).  general; prefer specifics; /biosyn permitted but consider also DNA REPLICATION; structural DNA models   
See Also DNA Primers; Genetic Code; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid
Examples DNA, A-Form; DNA Adducts; DNA, Algal; DNA, Antisense; DNA, Archaeal; DNA, B-Form; DNA, Bacterial; DNA, C-Form; DNA, Catalytic; DNA, Circular; DNA, Concatenated; DNA, Cruciform; DNA, Fungal; DNA, Helminth; DNA, Intergenic; DNA, Neoplasm; DNA, Plant; DNA, Protozoan; DNA, Recombinant; DNA, Ribosomal; DNA, Satellite; DNA, Single-Stranded; DNA Transposable Elements; DNA, Viral; DNA, Z-Form; Isochores; Retroelements 		Other names Deoxyribonucleic Acid; DNA, Double-Stranded; Double-Stranded DNA; ds DNA; DNA, Double Stranded; ds-DNA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5'-ACCaagtttcttcAGC-3'  0   *DNA Oligodeoxyribonucleotides, Antisense. Mol Cancer Ther. 2011 Dec;10(12):2309-19.
Derinat  0   *DNA. Ross Fiziol Zh Im I M Sechenova 2009 Mar;95(3):290-6
IRS 954  0   *DNA Toll-Like Receptor 7/antagonists & inhibitors Toll-Like Receptor 9/antagonists & inhibitors. Eur J Immunol 2007 Dec;37(12):3582-6
CpG phosphodiester ODN 46-O  0   *DNA. Int Arch Allergy Immunol 2007;144(4):315-24
CpG phosphorothioate ODN 1826-S  0   *DNA. Int Arch Allergy Immunol 2007;144(4):315-24
INEX 6303  0   *DNA. Int Immunopharmacol 2007 Aug;7(8):1064-75
d(CGCGATCGCG)2  0   *DNA. J Biol Inorg Chem 2007 Mar;12(3):279-92
d(TTAGGG)13  0   *DNA. Nucleic Acids Res 2007;35(9):2846-60
d(TTAGGG)4  0   *DNA. Nucleic Acids Res 2007;35(9):2846-60
d(G4(T4G4)3)  0   *DNA. Nucleic Acids Res 2007;35(8):2554-63
AQ 157TG  0   *DNA. Nucleic Acids Res 2006;34(6):1836-46
MB-FB molecular beacon  0   *DNA. Nucleic Acids Res 2006;34(6):e50
PX65 paranemic crossover DNA molecule  0   *DNA. Nucleic Acids Res 2004;32(20):6047-56
ZYC101a  0   *DNA. Obstet Gynecol 2004 Feb;103(2);317-26
ferrovir  0   *DNA *Ferric Compounds. Am Clin Lab 2001 Oct-Nov;20(9):36-8
calf thymus DNA  91080-16-9   *DNA.
Pharma Action Indicators and Reagents 		Biopolymers 1999;52(3):110-28
CpG ODN 1585  0   *DNA. Infect Immun 2001 Mar;69(3):1643-9
DVP-M-CHOP protocol  0   DNA *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Methotrexate Prednisolone Vincristine. Rinsho Ketsueki 1998 Mar;39(3):176-84
pentameric thymidyl deoxynucleic guanidine  0   *DNA *Guanidines. Proc Natl Acad Sci U S A 1995 Jun 20;92(13):6097-101
deoxynucleic guanidine  0   *DNA *Guanidines. Proc Natl Acad Sci U S A 1994 Aug 16;91(17):7864-8
amsacrine-DNA  0   *DNA *Amsacrine. Yao Hsueh Hsueh Pao 1992;27(11):801-5
luzopeptin-DNA complex  0   *DNA *Hydroxyquinolines. Biochemistry 1991;30(16):4026
DNA-Sephadex  0   *DNA *Dextrans. Arch Biochem Biophys 1989;268(1):35
DNA hydroperoxide  0   *DNA *Peroxides. Biochem J 1988;254(3):841
asialoorosomucoid-polylysine conjugate  0   *Asialoglycoproteins Orosomucoid/*analogs & derivatives Polylysine/*analogs & derivatives DNA Drug Carriers. J Biol Chem 1988;263(29):14621
calcium phosphate-DNA precipitate  0   *DNA *Calcium Phosphates. Nucleic Acids Res 1988;16(4):1371
ethidium-DNA complex  0   *DNA Ethidium/*analogs & derivatives. Biopolymers 1987;26(5):613
triplex DNA  0   *DNA Nucleic Acid Conformation. Nucleic Acids Res 1987;15(3):1047
DNA-iomethin  0   *DNA *Aminoquinolines. Int J Nucl Med Biol 1984;11(1):23
DNA-cellulose  0   *DNA Cellulose/*analogs & derivatives. Biochem J 1981;198(3):447
Okazaki fragments  0   *DNA DNA Replication DNA, Viral. Biochemistry 18(21):4563;1979; J Biol Chem 245(22):11495;1979
DNA-aldehydes  0   *DNA. Indian J Exp Biol 17(1):82;1979
kinked DNA  0   *DNA Nucleic Acid Conformation. Biochim Biophys Acta 478(1):9;1977
DNA-spermidine  37217-88-2   *DNA Spermidine/*analogs & derivatives. Nippon Acta Radiol 34(1):26;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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