encyclopedia of medical concepts
ψ 
ψ 
ψ 

Myeloid-Lymphoid Leukemia Protein

More information in Books or onNLM PubMed
Definition: Myeloid-lymphoid leukemia protein is a transcription factor that maintains high levels of HOMEOTIC GENE expression during development. The GENE for myeloid-lymphoid leukemia protein is commonly disrupted in LEUKEMIA and combines with over 40 partner genes to form FUSION ONCOGENE PROTEINS.      Other names Proto-Oncogene Protein, MLL; Proto Oncogene Proteins MLL; Myeloid Lymphoid Leukemia Protein; Mixed Lineage Leukemia Protein; MLL, Proto-Oncogene Proteins; MLL Proto Oncogene Protein; Zinc Finger Protein HRX; Proto-Oncogene Proteins MLL; Mixed-Lineage Leukemia Protein; MLL Proto-Oncogene Protein; Acute Lymphoblastic Leukemia Protein 1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MLL-AF9 fusion protein, mouse  0   *Oncogene Proteins, Fusion Myeloid-Lymphoid Leukemia Protein. Mol Cell 2010 Jun 25;38(6):853-63
MLL4 protein, human  0   *DNA-Binding Proteins Leukemia, Myeloid Myeloid-Lymphoid Leukemia Protein. Hum Mutat. 2008 May;29(5):703-8
Mll2 protein, mouse  0   *Myeloid-Lymphoid Leukemia Protein. Development 2006 Apr;133(8):1423-32
Mll protein, rat  0   *Myeloid-Lymphoid Leukemia Protein.
Mll protein, mouse  0   *Myeloid-Lymphoid Leukemia Protein.
MLL protein, human  0   *Myeloid-Lymphoid Leukemia Protein.
Mllt4 protein, mouse  0   *Myosins *Kinesin ras Proteins Myeloid-Lymphoid Leukemia Protein.
Mllt10 protein, mouse  0   *Transcription Factors Zinc Fingers Leucine Zippers Myeloid-Lymphoid Leukemia Protein.
Mllt3 protein, rat  0   *Nuclear Proteins Oncogene Proteins, Fusion Trans-Activators Myeloid-Lymphoid Leukemia Protein.
Mllt3 protein, mouse  0   *Nuclear Proteins Oncogene Proteins, Fusion Trans-Activators Myeloid-Lymphoid Leukemia Protein.
MLLT3 protein, human  0   *Nuclear Proteins Oncogene Proteins, Fusion Trans-Activators Myeloid-Lymphoid Leukemia Protein.
Mllt2h protein, mouse  0   *DNA-Binding Proteins *Nuclear Proteins Myeloid-Lymphoid Leukemia Protein.
Mllt6 protein, mouse  0   *DNA-Binding Proteins *Neoplasm Proteins Zinc Fingers Leucine Zippers Myeloid-Lymphoid Leukemia Protein.
MLL-AF-1p fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Int J Hematol 2003 Dec;78(5):439-42
MLL-EEN fusion protein, human  0   *Oncogene Proteins, Fusion *Nucleocytoplasmic Transport Proteins *Myeloid-Lymphoid Leukemia Protein. Blood. 2004 Feb 15;103(4):1445-53
MLL-MSF fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein Leukemia, Myelomonocytic, Acute. Int J Hematol 2002 Jun;75(5):503-7
MLL-AF9 fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Blood 2003 Apr 15;101(8):3229-35
MLL-ELL fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Blood 2003 Mar 15;101(6):2355-62
MLL-MPFYVE fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Oncogene 2003 Mar 6;22(9):1400-10
MLL-AF15q14 fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Oncogene 2003 Mar 6;22(9):1400-10
MLL-AF10 fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Mol Cell Biol 2003 Jan;23(1):119-30
MLL-CALM fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein Monomeric Clathrin Assembly Proteins. Genes Chromosomes Cancer 2003 Jan;36(1):26-36
MLL-LAF4 fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Genes Chromosomes Cancer 2002 Sep;35(1):92-6
MLL-AFX protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Mol Cell Biol 2002 Sep;22(18);6542-52
MLL5 protein, human  0   *DNA-Binding Proteins Leukemia, Myeloid Myeloid-Lymphoid Leukemia Protein. Oncogene 2002 Jul 18;21(31):4849-54
MLL3 protein, human  0   *DNA-Binding Proteins Myeloid-Lymphoid Leukemia Protein. Cancer Detect Prev 2001;25(5):454-69
MLL-AF6 fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein Leukemia, Myeloid. Leukemia 2001 Oct;15(10):1674-6
MLL-ENL oncoprotein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Oncogene 2001 Jan 25;20(4):411-9
MLL-GMPS fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Blood 2000 Dec 15;96(13):4360-2
AF3p21-MLL fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Blood 2000 Feb 1;95(3):1066-8
MLL2 protein, human  0   *DNA-Binding Proteins *Neoplasm Proteins Myeloid-Lymphoid Leukemia Protein. Genomics 1999 Jul 15;59(2):187-92
MLL-ABI1 fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein. Blood 1998 Aug 15;92(4):1125-30
MLL-AF4 fusion protein, human  0   *Oncogene Proteins, Fusion *Myeloid-Lymphoid Leukemia Protein Neoplasm Proteins Tumor Markers, Biological. Blood 1998 Aug 1;92(3):709-11
FOXO4 protein, human  0   *Transcription Factors Myeloid-Lymphoid Leukemia Protein. Hum Genet 1997 Oct;100(5-6):569-72; Oncogene 1997 Jan 16; 14(2):195-202
MLLT6 protein, human  0   *DNA-Binding Proteins *Neoplasm Proteins Zinc Fingers Leucine Zippers Myeloid-Lymphoid Leukemia Protein. Proc Natl Acad Sci U S A 1994 Aug 16;91(17):8107-11; Proc Natl Acad Sci U S A 1995 Oct 10;92(21):9737-41
MLLT4 protein, human  0   *Myosins *Kinesin ras Proteins Myeloid-Lymphoid Leukemia Protein. Trends Biochem Sci 1995 Jul;20(7):265-6
MLLT10 protein, human  0   *Transcription Factors Zinc Fingers Leucine Zippers Myeloid-Lymphoid Leukemia Protein. Blood 1995 Mar 15;85(6):1435-41
AFF1 protein, human  150826-18-9   *DNA-Binding Proteins *Nuclear Proteins Myeloid-Lymphoid Leukemia Protein. Proc Natl Acad Sci U S A 1993 May 15;90(10):4631-5
MLLT1 protein, human  0   *Neoplasm Proteins *Nuclear Proteins *Transcription Factors Myeloid-Lymphoid Leukemia Protein. Proc Natl Acad Sci U S A 1993 May 15;90(10):4631-5

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy