encyclopedia of medical concepts
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Matrix Metalloproteinase 12
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Definition
: A secreted matrix metalloproteinase which is highly expressed by MACROPHAGES where it may play a role in INFLAMMATION and WOUND HEALING.
Other names
Metalloproteinase, MMP12; Metalloproteinase, MMP-
12; Metalloproteinase 12, Matrix; Metalloelastase, Macrophage-
Specific; Metalloelastase, Macrophage; Macrophage Specific Metalloelastase; MMP 12 Metalloproteinase; Elastase, Metalloproteinase; Metalloproteinase Elastase; Macrophage-
Specific Metalloelastase; Macrophage Metalloelastase; MMP12 Metalloproteinase; MMP-
12 Metalloproteinase
Substance
CAS Registry & name
Categories
Source
Drugs
*
3-
methyl-
2-
(4-
(3-
p-
tolyl(1,2,4)oxadiazol-
5-
yl)benzenesulfonylamino)butyric acid
0
*Oxadiazoles
*Sulfonamides
Matrix Metalloproteinase 2/antagonists & inhibitors
Matrix Metalloproteinase 9/antagonists & inhibitors
Matrix Metalloproteinase 12/antagonists & inhibitors.
Endocr J 2011;58(2):101-7
RXP470.1 peptide
0
*Peptides
Matrix Metalloproteinase 12/antagonists & inhibitors.
Arterioscler Thromb Vasc Biol 2011 mar;31(3):528-35
2-
(8-
(methoxycarbonylamino)dibenzo(b,d)furan-
3-
sulfonamido)-
3-
methylbutanoic acid
0
*Benzofurans
*Sulfonamides
Matrix Metalloproteinase 12/antagonists & inhibitors.
J Med Chem 2009 Apr 9;52(7):1799-802
(diethyl((methylsulfinyl)methyl)phosphonate)(dimethylmalonato)platinum(II)
0
*Organoplatinum Compounds
Matrix Metalloproteinase 3/antagonists & inhibitors
Matrix Metalloproteinase 2/antagonists & inhibitors
Matrix Metalloproteinase 9/antagonists & inhibitors
Matrix Metalloproteinase 12/antagonists & inhibitors.
J Med Chem 2007 Jul 26;50(15):3434-41
dichloro(diethyl((methylsulfinyl)methyl)phosphonate)platinum(II)
0
*Organoplatinum Compounds
Matrix Metalloproteinase 3/antagonists & inhibitors
Matrix Metalloproteinase 2/antagonists & inhibitors
Matrix Metalloproteinase 9/antagonists & inhibitors
Matrix Metalloproteinase 12/antagonists & inhibitors.
J Med Chem 2007 Jul 26;50(15):3434-41
MMP12 protein, human
EC 3.4.24.65
*Matrix Metalloproteinase 12.