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Matrix Metalloproteinase 9

More information in Books or onNLM PubMed
Definition: An endopeptidase that is structurally similar to MATRIX METALLOPROTEINASE 2. It degrades GELATIN types I and V; COLLAGEN TYPE IV; and COLLAGEN TYPE V.      Other names Metalloproteinase, MMP9; Metalloproteinase, MMP-9; Metalloproteinase 9, Matrix; MMP 9 Metalloproteinase; 92 kDa Type IV Collagenase; 92 kDa Gelatinase; Matrix Metalloproteinase-9; MMP9 Metalloproteinase; MMP-9 Metalloproteinase; 92-kDa Type IV Collagenase; 92-kDa Gelatinase; Gelatinase B
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
saucerneol G  0   *Lignans Matrix Metalloproteinase 9/antagonists & inhibitors. Biol Pharm Bull 2010;33(12):1944-8
3-methyl-2-(4-(3-p-tolyl(1,2,4)oxadiazol-5-yl)benzenesulfonylamino)butyric acid  0   *Oxadiazoles *Sulfonamides Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors Matrix Metalloproteinase 12/antagonists & inhibitors. Endocr J 2011;58(2):101-7
methyl 6-(benzyloxycarbonylamino)-2-(2-(2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetamido)hexanoate  0   *Benzamides *Piperidones Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors. Anticancer Drugs 2008 Nov;19(10):957-65
3,4,5-trihydroxybenzaldehyde  0   *Benzaldehydes Matrix Metalloproteinase 9/antagonists & inhibitors. J Cell Biochem 2008 Oct 1;105(2):524-33
5-methyl-2-(4-methylphenyl)-1H-benzimidazole  0   *Benzimidazoles Matrix Metalloproteinase 9/antagonists & inhibitors. Mol Pharmacol 2008 Mar;73(3):919-29
2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone  0   *Dioxoles *Quinolones Matrix Metalloproteinase 9/antagonists & inhibitors. Cancer Lett 2007 Nov 8;257(1):87-96
(diethyl((methylsulfinyl)methyl)phosphonate)(dimethylmalonato)platinum(II)  0   *Organoplatinum Compounds Matrix Metalloproteinase 3/antagonists & inhibitors Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors Matrix Metalloproteinase 12/antagonists & inhibitors. J Med Chem 2007 Jul 26;50(15):3434-41
dichloro(diethyl((methylsulfinyl)methyl)phosphonate)platinum(II)  0   *Organoplatinum Compounds Matrix Metalloproteinase 3/antagonists & inhibitors Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors Matrix Metalloproteinase 12/antagonists & inhibitors. J Med Chem 2007 Jul 26;50(15):3434-41
MMP-9-hemopexin  0   *Hemopexin *Matrix Metalloproteinase 9. Int J Oncol 2007 Apr;30(4):985-92
SM 7368  0   *Benzamides *Thiazoles Matrix Metalloproteinase 9/antagonists & inhibitors. Biochem Biophys Res Commun 2005 Oct 21;336(2):716-22
Mmp9 protein, mouse  EC 3.4.24.-   *Matrix Metalloproteinase 9. Int J Cancer 2005 Aug 10;116(1):52-61
phenyl caffeate  0   *Caffeic Acids Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors. FASEB J 2004 Nov;18(14):1670-81
2-((4-biphenylsulfonyl)amino)-3-phenylpropionic acid  0   *Sulfonamides Phenylalanine/*analogs & derivatives Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors. Cell Death Differ 2003 May;10(5):558-69
YLL 224  0   *Imines *Indoles Matrix Metalloproteinase 3/antagonists & inhibitors Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors Matrix Metalloproteinase 1/antagonists & inhibitors Matrix Metalloproteinase 7/antagonists & inhibitors Matrix Metalloproteinase 8/antagonists & inhibitors. Biochem Biophys Res Commun 2000 Aug 11;274(3):780-6
MAG 283  0   *Amides *Sulfhydryl Compounds Matrix Metalloproteinase 3/antagonists & inhibitors Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors Matrix Metalloproteinase 1/antagonists & inhibitors Matrix Metalloproteinase 7/antagonists & inhibitors Matrix Metalloproteinase 8/antagonists & inhibitors. Biochem Biophys Res Commun 2000 Aug 11;274(3):780-6
pro-matrix metalloproteinase 9  EC 3.4.24.-   *Enzyme Precursors *Matrix Metalloproteinase 9. Ann N Y Acad Sci 1999 Jun 30;878:372-87

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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