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Receptors, Thrombopoietin
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Definition
: Cell surface receptors that are specific for THROMBOPOIETIN. They signal through interaction with JANUS KINASES such as JANUS KINASE 2.
Other names
Receptor, Thrombopoietin; Receptor, MPL Ligand; Ligand Receptor, MPL; Thrombopoietin Receptors; Thrombopoietin Receptor; MPL Ligand Receptor; CD110 Antigens; Antigens, CD110
Substance
CAS Registry & name
Categories
Source
Drugs
*
ALXN4100TPO
0
*Antibodies, Monoclonal
*Thrombopoietin
Receptors, Thrombopoietin/agonists.
Radiat Res. 2011 Jun;175(6):746-58
1-
(3-
chloro-
5-
((4-
(4-
chloro-
2-
thienyl)-
5-
(4-
cyclohexylpiperazin-
1-
yl)thiazol-
2-
yl)carbamoyl)-
2-
pyridyl)piperidine-
4-
carboxylic acid
0
*Thiazoles
*Thiophenes
Receptors, Thrombopoietin/agonists.
Exp Hematol 2008 Oct;36(10):1337-42
thrombopoietin mimetic peptide
0
*Peptides
Receptors, Thrombopoietin/agonists.
Science 1997 Jun 13;276(5319):1696-9
romiplostim
0
*Receptors, Fc
*Recombinant Fusion Proteins
*Thrombopoietin
Receptors, Thrombopoietin/agonists.
Cytokine 2004 Jan 21;25(2):52-60
NPLATE
Mpl protein, mouse
0
*Receptors, Thrombopoietin.
EMBO J 1993 Jul;12(7):2645-53
MPL protein, human
143641-95-6
*Receptors, Thrombopoietin
Thrombopoietin.
Embo J 1993 Jul;12(7):2645-53; Proc Natl Acad Sci USA 1992 Jun 15;89(12):5640-4