encyclopedia of medical concepts
ψ 
ψ 

Topoisomerase I Inhibitors

More information in Books or onNLM PubMed
Definition: Compounds that inhibit the activity of DNA TOPOISOMERASE I.      Other names Inhibitors, Topoisomerase I; Inhibitors, Topoisomerase 1; DNA Type 1 Topoisomerase Inhibitors; DNA Topoisomerase I Inhibitors; Topoisomerase 1 Inhibitors
Substances having this pharmacologic action: Topotecan; Camptothecin; belotecan; exatecan; 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one; irinotecan
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cyclohexyl(2-phenylquinazolin-4-yl)amine  0   *Cyclohexylamines *Quinazolines DNA Topoisomerases, Type I Topoisomerase I Inhibitors. Bioorg Med Chem. 2011 Jul 15;19(14):4399-404.
7-phenyl-6H-(1,2,5)oxadiazolo(3,4-e)indole 3-oxide  0   *Indoles *Oxadiazoles Topoisomerase I Inhibitors. Biochem Biophys Res Commun. 2011 May 27;409(1):75-81

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy