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dasatinib

under Pyrimidines
More information in Books or onNLM PubMed
More on Pyrimidines Definition: A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dasatinib [ Sprycel,(18F)-N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide,BMS 354825,BMS-354825,BMS354825,N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide ]
  antineoplastic; an ABL kinase inhibitor that counters resistance to imatinib; structure in first source
302962-49-8   *Pyrimidines *Thiazoles Fluorine Radioisotopes Protein-Tyrosine Kinases/antagonists & inhibitors Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Pharma Action Protein Kinase Inhibitors
Science 2004 Jul 16;305(5682):399-401 SPRYCEL

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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