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Acetyl-CoA C-Acyltransferase

More information in Books or onNLM PubMed
Definition: Enzyme that catalyzes the final step of fatty acid oxidation in which ACETYL COA is released and the CoA ester of a fatty acid two carbons shorter is formed.  do not confuse with ACETYL-COA C-ACETYLTRANSFERASE   
See Also Acetyl-CoA C-Acetyltransferase
Other names 3-Ketoacyl CoA Thiolase; beta-Ketothiolase; Acetyl Coenzyme A Acyltransferase; Acetyl CoA Acyltransferase; 3-Ketothiolase; beta Ketothiolase; beta Ketoacyl Thiolase; Thiolase, beta-Ketoacyl; Thiolase, 3-Oxoacyl-Coenzyme A; Thiolase, 3-Oxoacyl CoA; Thiolase, 3-Ketoacyl CoA; Thiolase, 2-Methylacetoacetyl CoA; CoA Thiolase, 3-Oxoacyl; CoA Thiolase, 3-Ketoacyl; CoA Thiolase, 2-Methylacetoacetyl; CoA Acyltransferase, Acetyl; C-Acyltransferase, Acetyl-CoA; Acyltransferase, Acetyl CoA; Acetyl CoA C Acyltransferase; beta-Ketoacyl Thiolase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ACAA1 protein, human  EC 2.3.1.16   *Acetyl-CoA C-Acyltransferase. BMC Med Genet. 2011;12() (dup#96):158
Beta ketothiolase deficiency  0   *Amino Acid Metabolism, Inborn Errors Acetyl-CoA C-Acyltransferase/deficiency.
2-Methylacetoacetyl CoA thiolase deficiency  0   *Amino Acid Metabolism, Inborn Errors Acetyl-CoA C-Acyltransferase/deficiency.
3-ketoacyl-CoA thiolase-2, Arabidopsis  EC 2.3.1.16   *Acetyl-CoA C-Acyltransferase *Arabidopsis Proteins. J Exp Bot 2007;58(11):2959-68
Acaa1b protein, mouse  EC 2.3.1.16   *Acetyl-CoA C-Acyltransferase. BMC Biochem 2004 Mar 25;5(1):3
Acaa1a protein, mouse  EC 2.3.1.16   *Acetyl-CoA C-Acyltransferase. BMC Biochem 2004 Mar 25;5(1):3
3-oxoadipyl-coenzyme A thiolase  EC 2.3.1.174   *Acetyl-CoA C-Acyltransferase. J Bacteriol 2002 Jan;184(1):207-15
PLTPAO protein, Aspergillus oryzae  EC 2.3.1.16   *Acetyl-CoA C-Acyltransferase *Fungal Proteins. Gene 2001 Jan 10;262(1-2):61-72
2-bromododecanoate  111-56-8   *Lauric Acids Acetyl-CoA C-Acyltransferase/antagonists & inhibitors. Arch Biochem Biophys 1990;281(2):233
2-chloro-6-phenylhexanoate  128409-71-2   *Caproates Acetyl-CoA C-Acyltransferase/antagonists & inhibitors. J Biol Chem 1990;265(16):9214
4-bromo-2-octenoic acid  115185-86-9   *Fatty Acids, Monounsaturated Acetyl-CoA C-Acyltransferase/antagonists & inhibitors. Biochemistry 1988;27(16):5995
fatty acid oxidation complex  0   *Acetyl-CoA C-Acyltransferase *Enoyl-CoA Hydratase *3-Hydroxyacyl CoA Dehydrogenases *Carbon-Carbon Double Bond Isomerases *Racemases and Epimerases. J Biol Chem 1983;258(16):9780

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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