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Racemases and Epimerases

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Definition: Enzymes that catalyze inversion of the configuration around an asymmetric carbon in a substrate having one (racemase) or more (epimerase) center(s) of asymmetry. (Dorland, 28th ed) EC 5.1.     
Examples Amino Acid Isomerases; Carbohydrate Epimerases 		Other names Epimerases and Racemases; Racemases; Epimerases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
decaprenylphosphoryl-beta-D-ribose 2'-epimerase, mouse  EC 5.1.-   *Racemases and Epimerases. Science. 2009 May 8;324(5928):801-4
fatty acid-CoA racemase, Mycobacterium tuberculosis  EC 5.1.-   *Racemases and Epimerases. Proteins 2006 Aug 15;64(3):817-22
imidodisuccinate epimerase, Agrobacterium tumefaciens  EC 5.1.-   *Racemases and Epimerases. Acta Crystallograph Sect F Struct Biol Cryst Commun 2006 Aug 1;62(Pt 8):746-9
alanylglutamic acid epimerase, E coli  EC 5.1.-   *Racemases and Epimerases *Escherichia coli Proteins. Biochemistry 2005 Sep 6;44(35):11722-9
VanT(E) protein, Enterococcus faecalis  EC 5.1.1.-   *Racemases and Epimerases. J Bacteriol 2002 Dec;184(23):6457-64
lpcA protein, E coli  EC 5.1.3.-   *Racemases and Epimerases *Escherichia coli Proteins. J Bacteriol 2002 Jan;184(2):363-9
NDP-4-keto-6-deoxy-D-glucose 3',5'-epimerase  EC 5.1.3.-   *Racemases and Epimerases. J Bacteriol 2001 Oct;183(19):5632-8
HSD17B6 protein, human  EC 5.1.-   *Racemases and Epimerases. J Biol Chem 2000 Sep 22;275(38);29452-7
serine racemase  EC 5.1.1.16   *Racemases and Epimerases Membrane Proteins. Mol Microbiol 1999 Mar;31(6):1653-64
rTS protein, human  0   *Proteins Racemases and Epimerases. Nucleic Acids Res 1993 Apr 25;21(8):1747-52
alpha-methylacyl-CoA racemase  EC 5.1.99.4   *Racemases and Epimerases. Eur J Biochem 1994 Jun 1;222(2):313-23
NeuC protein, Neisseria meningitidis  EC 5.1.3.-   *Bacterial Proteins *Racemases and Epimerases. Mol Microbiol 1994 Oct;14(1):141-9
caiD protein, E coli  EC 5.1.-   *Racemases and Epimerases *Escherichia coli Proteins. Mol Microbiol 1994 Sep;13(5):775-86
2-arylpropionyl-CoA epimerase  EC 5.1.99.-   *Racemases and Epimerases. J Biol Chem 1993 Feb 15;268(5):3487-93
hydantoin racemase  EC 5.1.99.-   *Racemases and Epimerases Pseudomonas. J Bacteriol 1992 Jun;174(11):3461-6
fatty acid oxidation complex  0   *Acetyl-CoA C-Acyltransferase *Enoyl-CoA Hydratase *3-Hydroxyacyl CoA Dehydrogenases *Carbon-Carbon Double Bond Isomerases *Racemases and Epimerases. J Biol Chem 1983;258(16):9780
3-hydroxybutyryl-CoA epimerase  EC 5.1.2.3   *Racemases and Epimerases. J Biol Chem 1981;256(8):4894
D-erythro-dihydroneopterin triphosphate epimerase protein, E coli  EC 5.1.99.-   *Racemases and Epimerases *Escherichia coli Proteins. Biochim Biophys Acta 411(2):236;1975
methylmalonyl-coenzyme A racemase  EC 5.1.99.1   *Racemases and Epimerases. Pediatr Res 9(7):559;1975
mandelate racemase  EC 5.1.2.2   *Racemases and Epimerases. Adv Enzymol 50:325;1979; Anal Biochem 94(2):329;1979; Biochemistry 13(12):2528;1974; Biochemistry 16(6):1123;1977; Methods Enzymol 46:541;1977
lactate racemase  EC 5.1.2.1   *Racemases and Epimerases. Biochim Biophys Acta 429(3):103;1976
aminopropanol racemase  EC 5.1.-   *Racemases and Epimerases. Biochem J 138(2):263;1974
allantoin racemase  EC 5.1.99.3   *Racemases and Epimerases. Biochim Biophys Acta 391(1):240;1975; J Biochem (Tokyo) 84(4):891;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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