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Carbon-Carbon Double Bond Isomerases

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Definition: Enzymes that catalyze the shifting of a carbon-carbon double bond from one position to another within the same molecule. EC 5.3.3.     
Examples Steroid Isomerases 		Other names C-C Double Bond Isomerases; Carbon Carbon Double Bond Isomerases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
isopentenyl-dimethylallyl diphosphate isomerase, Nicotiana benthamiana  EC 5.3.3.-   *Carbon-Carbon Double Bond Isomerases. Plant Physiol 2004 Apr;134(4):1401-13
2-cycloheneylcarbonyl-CoA isomerase  EC 5.3.3.-   *Carbon-Carbon Double Bond Isomerases. Biochemistry 2000 Jun 27;39(25):7595-604
DCI1 protein, S cerevisiae  EC 5.3.3.-   *Membrane Proteins *Carbon-Carbon Double Bond Isomerases *Saccharomyces cerevisiae Proteins. Biochem Biophys Res Commun 1999 Jun 24;260(1):28-34
ECI2 protein, human  EC 5.3.3.8   *Carbon-Carbon Double Bond Isomerases. Biochim Biophys Acta 1999 May 31;1454(1):126-31
delta(3,5,7),delta(2,4,6)-trienoyl-CoA isomerase  EC 5.3.3.-   *Carbon-Carbon Double Bond Isomerases. J Biol Chem 1999 May 14;274(20):13830-5
polyenoic fatty acid isomerase  EC 5.3.3.-   *Carbon-Carbon Double Bond Isomerases. Biochemistry 1997 Mar 11;36(10):2985-92
muconolactone delta-isomerase  EC 5.3.3.4   *Bacterial Proteins *Carbon-Carbon Double Bond Isomerases. J Bacteriol 1998 May;180(9):2367-72
delta(3,5),delta(2,4)-dienoyl-CoA isomerase  EC 5.3.3.-   *Carbon-Carbon Double Bond Isomerases. J Biol Chem 1994 Jan 28;269(4):2384-8
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase  EC 5.3.3.-   *Carbon-Carbon Double Bond Isomerases. Eur J Biochem 1993 OCt 15;217(2):575-80
3-methylitaconate delta-isomerase  EC 5.3.3.6   *Carbon-Carbon Double Bond Isomerases. Eur J Biochem 1989;184(1):103
isopiperitenone delta-isomerase  EC 5.3.3.11   *Carbon-Carbon Double Bond Isomerases. Arch Biochem Biophys 1985;238(1):49
fatty acid oxidation complex  0   *Acetyl-CoA C-Acyltransferase *Enoyl-CoA Hydratase *3-Hydroxyacyl CoA Dehydrogenases *Carbon-Carbon Double Bond Isomerases *Racemases and Epimerases. J Biol Chem 1983;258(16):9780
5-carboxymethyl-2-hydroxymuconate delta-isomerase  EC 5.3.3.10   *Carbon-Carbon Double Bond Isomerases. Eur J Biochem 1981;117(3):581
vinylacetyl-CoA delta-isomerase  EC 5.3.3.3   *Carbon-Carbon Double Bond Isomerases. FEBS Lett 33(1):81;1973
isopentenyldiphosphate delta-isomerase  EC 5.3.3.2   *Carbon-Carbon Double Bond Isomerases. Arch Biochem Biophys 184(2):381;1977; J Bacteriol 123(1):385;1975; J Biol Chem 248(23):8043;1973
dodecenoyl-coenzyme A delta-isomerase  EC 5.3.3.8   *Carbon-Carbon Double Bond Isomerases. Hoppe Seylers Z Physiol Chem 359(12):1777;1978; Lipids 1979;14(11):943
aconitate delta-isomerase  EC 5.3.3.7   *Carbon-Carbon Double Bond Isomerases.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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