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Astatine

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Definition: Astatine. A radioactive halogen with the atomic symbol At, atomic number 85, and atomic weight 210. Its isotopes range in mass number from 200 to 219 and all have an extremely short half-life. Astatine may be of use in the treatment of hyperthyroidism.  naturally radioactive; IM   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-succinimidyl 3-astato-5-guanidinomethylbenzoate  0   *Guanidines Astatine. Int J Radiat Oncol Biol Phys 2008 Sep 1;72(1):193-200
(1,5,9,13-tetrathiacyclohexadecane-3,11-diol)iridium(III) astatide  0   *Organometallic Compounds Astatine. Bioconjug Chem 2008 Apr;19(4):958-65
(1,5,9,13-tetrathiacyclohexadecane-3,11-diol)rhodium(III) astatide  0   *Organometallic Compounds Astatine. Bioconjug Chem 2008 Apr;19(4):958-65
meta-((211)At)astatobenzylguanidine  0   Guanidine/*analogs & derivatives Astatine. Bioorg Med Chem. 2007 May 15;15(10):3430-6
211At-labeled monoclonal antibody MX35  0   *Antibodies, Monoclonal *Organometallic Compounds Astatine. J Nucl Med 2005 Nov;46(11):1907-15
N-succinimidyl 3-astatobenzoate  0   *Benzoates *Succinimides Astatine. J Nucl Med 2005 Aug;46(8):1393-400
N-succinimidyl N-(4-astatophenethyl)succinamate  0   *Succinimides Astatine. Nucl Med Biol 2001 Oct;28(7):845-56
5-astato-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracyl  0   Arabinofuranosyluracil/*analogs & derivatives Astatine. Nucl Med Biol 1998 Jul;25(5):487-96
((5-astato-3-pyridinyl)carbonyl)norbiotinamide  0   Biotin/*analogs & derivatives Astatine. Nucl Med Biol 1998 Feb;25(2):81-8
(3-astatobenzoyl)norbiotinamide  0   Biotin/*analogs & derivatives Astatine. Nucl Med Biol 1998 Feb;25(2):81-8
biotinyl-3-astatoanilide  0   Biotin/*analogs & derivatives Astatine. Nucl Med Biol 1997 Feb;24(2):135-43
5-astato-2'-deoxyuridine  63473-09-6   Idoxuridine/*analogs & derivatives Astatine. Cancer Res 1996 Mar 15;56(6):1204-9
4-astato-N-piperidinoethylbenzamide  0   *Benzamides *Piperidines Astatine. Nucl Med Biol 1995 May;22(4):467-73
1-(3-astatobenzyl)guanidine  127367-45-7   *Guanidines Astatine. Bioconjug Chem 1992 Nov-Dec;3(6):499-503
6-astatomethyl-19-norcholest-5(10)-en-3-ol  101387-37-5   *Astatine Cholesterol/*analogs & derivatives. Int J Appl Radiat Isot 1985;36(7):561
astato-2-methyl-1,4-naphthoquinol diphosphate  81781-58-0 1,4-Naphthalenediol, 6-(astato-211At)-2-methyl-, bis(dihydrogen phosphate), tetrasodium salt  *Astatine Vitamin K 3/*analogs & derivatives. Int J Appl Radiat Isot 1982;33(1):75

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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