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Clofibrate

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Definition: A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)     
Pharmacological Action Anticholesteremic Agents; Hypolipidemic Agents 		Other names Chlorophenoxyisobutyrate, Ethyl; Miskleron; Miscleron; Ethyl Chlorophenoxyisobutyrate; Clofibric Acid, Ethyl Ester; Atromid S; Atromid; AthromidinDrugs* : CLOFIBRATE; ATROMID-S
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
VULM 1457  0   Clofibrate/*analogs & derivatives. Pharmazie. 2005 Sep;60(9):714-5
AL 294  62516-91-0 Benzenepropanoic acid, alpha-chloro-4-(2-methyl-2-phenylpropoxy)-, ethyl ester  Clofibrate/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1990;38(10):2792
ML 1037  47662-72-6   Clofibrate/*analogs & derivatives. Int J Radiat Oncol Biol Phys 1989;16(5):1183
ethyl 2,5-dimethylphenoxyisobutyrate  102416-49-9   Clofibrate/*analogs & derivatives. Yao Hsueh Hsueh Pao 1985;20(11):827
beclobrinic acid  71548-88-4   Clofibrate/*analogs & derivatives. Life Sci 1985;37(1):63
clofibrate mercapturate  84489-15-6 L-Cysteine, N-acetyl-, 2-(4-chlorophenoxy)-2-methylpropanoate (ester)  Clofibrate/*analogs & derivatives. Drug Metab Dispos 1982;110(6):609
azidofibrate  82054-49-7 Propanoic acid, 2-(4-azidophenoxy)-2-methyl-, ethyl ester  Clofibrate/*analogs & derivatives. Arzneimittelforsch 1982;32(3):186
2-(4-chlorophenoxy)-2-methylpropanamide  5658-61-7 Propanamide, 2-(4-chlorophenoxy)-2-methyl  Clofibrate/*analogs & derivatives. J Anal Toxicol 1981;5(4):194
ethyl-(p-chlorophenoxy)-3-hydroxy-3-methylpentanoate  77087-97-9 Pentanoic acid, 5-(4-chlorophenoxy)-3-hydroxy-3-methyl-, ethyl ester  Clofibrate/*analogs & derivatives. Atherosclerosis 1981;38(3-4):411
etofyllinclofibrate  54504-70-0   Clofibrate/*analogs & derivatives.
Pharma Action Hypolipidemic Agents ; Antioxidants ; Radiation-Sensitizing Agents 		Arzneim Forsch 1980;30(11b):2014
lysine clofibrate  77111-08-1 L-Lysine, 2-(4-chlorophenoxy)-2-methylpropanoate  Clofibrate/*analogs & derivatives. Arch Sci Med (Torino) 1980;137(1):131
urefibrate  38647-79-9 acetamide, N-(aminocarbonyl)-2,2-bis(4-chlorophenoxy)  Clofibrate/*analogs & derivatives. J Chromatogr 1980;191:261
3-nicotinoyloxypropyl 4-chlorophenoxyisobutyrate  42597-57-9 3-pyridinecarboxylic acid, 3-(2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy)propyl ester  Clofibrate/*analogs & derivatives. Clin Ter 89(2):127;1979; Clin Ter 89(3):267;1979
clobuzarit  22494-47-9 Propanoic acid, 2-((4'-chloro(1,1'-biphenyl)-4-yl)methoxy)-2-methyl  Clofibrate/*analogs & derivatives. Thromb Haemost 40(1):75;1978
7-chloro-3a,8b-dihydro-3a-methylfuro(3,4-b)benzofuran-3(lH)-one  59874-49-6   Clofibrate/*analogs & derivatives. J Med Chem 19(10):1214;1976
N 041  63414-31-3   *Clofibrate *Phosphatidylcholines Drug Combinations. MMW 118(36):1127;1976
beta-diethylaminoethyl alpha-4-chlorophenoxyisobutyrate  56135-48-9 2-(4-chlorophenoxy)-2-methylpropanoic acid 2-(diethylamino)ethyl ester.HCl  Clofibrate/*analogs & derivatives. Mech Ageing Dev 5(1):39;1976
angiokapsul  76705-38-9 myo-Inositol, hexa-3-pyridinecarboxylate, mixt. with ethyl 2-(4-chlorophenoxy)-2-methylpropanoate  *Clofibrate Drug Combinations Inositol/*analogs & derivatives. Med Welt 26(14):655;1975
eramide  0   *Clofibrate *Practolol Drug Combinations. Drug Ther Bull 12(25):99;1974
pyridoxine clofibrate  29952-87-2   Clofibrate/*analogs & derivatives Pyridoxine/*analogs & derivatives. Nouv Presse Med 2(46):3115;1973
liporeduct  57456-45-8   *Clofibrate *Nicotinic Acids Drug Combinations Inositol/*analogs & derivatives. Ther Ggw 113(5):813;1974
clofibride  26717-47-5 2-(4-chlorophenoxy)-2-methylpropanoic acid, 4-(dimethylamino)-4-oxobutyl ester  Clofibrate/*analogs & derivatives. Biomedicine 1979;30(5):249; Eur J Pharmacol 43(1):57;1977; Eur J Toxicol 5(4):237;1972; Lille Med 18(10) suppl 5:1292;1973; Sem Hop Ther 52(9):455;1976
beta-pyridylcarbinol clofibrate  62277-32-1   *Clofibrate *Nicotinyl Alcohol Drug Combinations. Minerva Med 64(16):751;1973
simfibrate  14929-11-4   Clofibrate/*analogs & derivatives. Clin Ter 88(4):267;1979; Clin Ter 88(5):481;1979; Curr Ther Res 19(1):145;1976
octotiamine  137-86-0   *Clofibrate *Nicotinic Acids *Nicotinyl Alcohol *Pemoline Drug Combinations Vitamins. Allgem Med 48(26):1199;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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