encyclopedia of medical concepts
ψ 
ψ 

Inositol

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Definition: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.     
Pharmacological Action Vitamin B Complex
Examples Inositol Phosphates 		Other names Myoinositol; Chiro Inositol; Mesoinositol; Chiro-Inositol
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-hydroxyphenylacetyl-3-D-chiro-inositol ester  0   Inositol/*analogs & derivatives. J Asian Nat Prod Res. 2012 Feb;14(2);182-5
2,4,5,6-tetra-O-benzyl-D-myo-inositol  0   *Benzyl Compounds Inositol/*analogs & derivatives. Org Lett. 2011 Oct 21;13(20):5496-9
1l-1,5-di-O-p-hydroxyphenylacetyl-chiro-inositol  0   Inositol/*analogs & derivatives. Carbohydr Res. 2010 Jan 11;345(1):172-4
(18F)-1-deoxy-1-fluoro-scyllo-inositol  0   Inositol/*analogs & derivatives. Chem Commun (Camb). 2009 Oct 7;(37):5527-9
4,6-di-O-acetyl-2-O-tosyl-myo-inositol 1,3,5-orthobenzoate  0   *Benzoates Inositol/*analogs & derivatives. Acta Crystallogr C. 2009 Jul;65(Pt 7):o335-8
4,6-di-O-acetyl-2-O-tosyl-myo-inositol 1,3,5-orthoformate  0   *Formates Inositol/*analogs & derivatives. Acta Crystallogr C. 2009 Jul;65(Pt 7):o335-8
6-O-acryloyl-2-O-benzoyl-myo-inositol 1,3,5,-orthoformate  0   *Acrylates Inositol/*analogs & derivatives. Acta Crystallogr C 2009 Feb;65(Pt 2):o54-7
inositol-1,2,3,5-tetra angelate  0   Inositol. Fitoterapia. 2008 Jul;79(5):393-4
cis-1,2,3,5-trans-4,6-inositol-2,3,6-triangelate  0   Inositol/*analogs & derivatives. Fitoterapia. 2008 Jul;79(5):393-4
4''-epi-validamycin A  0   Inositol/*analogs & derivatives. J Nat Prod 2008 Jul;71(7):1233-6
2,4(6)-di-O-benzoyl-6(4)-O-((7,7-dimethyl-2-oxobicyclo(2.2.1)heptan-1-ylmethyl)sulfonyl)-myo-inositol 1,3,5-orthoacetate  0   Inositol/*analogs & derivatives. Acta Crystallogr C 2007 Sep;63(Pt 9):o555-8
4-O-(4-vinylbenzyl)-myo-inositol 1,3,5-orthoformate  0   Inositol/*analogs & derivatives. J Pharm Pharmacol 2007 Apr;59(4):597-601
vibo-quercitol  0   Inositol/*analogs & derivatives. J Nat Prod 2007 Mar;70(3):493-7
methylinositol  0   Inositol/*analogs & derivatives. Nat Prod Res. 2006 Sep;20(11):999-1007
6-(ortho-nitroveratryl)-caged IP3  0   *Nitro Compounds *Organophosphorus Compounds Inositol/*analogs & derivatives. Chembiochem. 2006 Jan;7(1):174-80
discoside  0   *Glycolipids Inositol/*analogs & derivatives. J Nat Prod 2005 Oct;68(10):1527-30
D-chiro-inositol-galactosamine  0   *Inositol Galactosamine/*analogs & derivatives. Biochemistry. 2005 Aug 23;44(33):11067-73
galactopyranosyl-(1-3)-1-O-methyl-1-inositol  0   *Galactosides Inositol/*analogs & derivatives. Carbohydr Res 2005 May 23;340(7):1441-6
1-O-acetyl-2,3-5,6-di-O-isopropylideneinositol  0   Inositol/*analogs & derivatives. Carbohydr Res 2004 Jul 12;339(10):1803-7
1,2-4,5-di-O-isopropylidene-allo-inositol  0   Inositol/*analogs & derivatives. Carbohydr Res 2004 Jun 1;339(8):1551-5
1D-3-deoxy-3-hydroxymethyl-myo-inositol  0   Inositol/*analogs & derivatives. Org Lett. 2003 Nov 13;5(23):4457-9
1D-1,4-di-O-(O-acetylmandeloyl)-2,3-5,6-di-O-isopropylidene-myo-inositol  0   *Mandelic Acids Inositol/*analogs & derivatives. Carbohydr Res 2004 Mar 15;339(4):807-11
proto-quercitol  0   Inositol/*analogs & derivatives. Carbohydr Res. 2003 Jul 29;338(16):1615-9
1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate  0   Inositol/*analogs & derivatives. Leukemia 2003 Sep;17(9):1794-805
1,6-di-O-feruloyl-myo-inositol  0   Inositol/*analogs & derivatives. J Org Chem 2001 Oct 19;66(21):7199-201
6-O-benzoyl-1,2-4,5-di-O-isopropylidene-myo-inositol  0   Inositol/*analogs & derivatives. hydr Res 2002 Jan 7;337(1):75-8
1,2-5,6-di-O-isopropylidene-myo-inositol  0   Inositol/*analogs & derivatives. hydr Res 2002 Jan 7;337(1):75-8
phosphatidyl-3-deoxy-3-aminoethyl-inositol  0   Inositol/*analogs & derivatives Phosphatidylinositol 3-Kinases. Bioorg Med Chem. 2001 Dec;9(12):3165-72
talo-quercitol  0   Inositol/*analogs & derivatives. J Org Chem 2001 Dec 14;66(25):8370-8
allo-quercitol  0   Inositol/*analogs & derivatives. J Org Chem 2001 Dec 14;66(25):8370-8
(1,4,7,10,13,16-hexaoxacyclooctadecane)potassium 2-O-benzoyl-1,3,5-O-methylidyne-myo-inositol 4,6-cyclophosphate trihydrate  0   Inositol/*analogs & derivatives. Acta Crystallogr C 2001 Oct;57(Pt 10):1147-8
D-myo-inositol-2,3,6-trisphosphate  0   Inositol/*analogs & derivatives. Bioorg Med Chem Lett 2001 Oct 22;11(20):2705-8
D-myo-inositol-1,3,4-trisphosphate  0   Inositol/*analogs & derivatives. Bioorg Med Chem Lett 2001 Oct 22;11(20):2705-8
D-myo-inositol-1,2,4-trisphosphate  0   Inositol/*analogs & derivatives. Bioorg Med Chem Lett 2001 Oct 22;11(20):2705-8
1,3,5-trideoxy-1,3,5-tris(dimethylamino)-cis-inositol  0   Inositol/*analogs & derivatives. Inorg Chem 2001 Sep 10;40(19):4918-27
5-epi-(6-(2)H2)valiolone  0   Inositol/*analogs & derivatives. J Org Chem 2001 Jul 27;66(15):5066-73
4,6-di-O-benzyl-myo-inositol  0   *Benzyl Compounds Inositol/*analogs & derivatives. Carbohydr Res 2001 Feb 15;330(3):409-11
inositol 4-(hexadecyloxy)-3-methoxybutanephosphonate  0   Inositol/*analogs & derivatives. Biochem Pharmacol 1999 May 15;57(10):1153-8
1-inosityl-2-acetamido-2-deoxyglucopyranoside  0   Acetylglucosamine/*analogs & derivatives Inositol/*analogs & derivatives. J Bacteriol 2000 Dec;182(24):6958-63
inositol 4,6-carbonate  0   *Carbonates Inositol/*analogs & derivatives. J Inorg Biochem 2000 Mar;78(4):313-20
3,4,5,6-tetra-O-acetyl-1,2-di-O-(3-(4'-acetoxy-3'-methoxyphenyl)-2-propenoyl)myo-inositol  0   Inositol/*analogs & derivatives. Bioorg Med Chem Lett. 2000 Jul 3;10(13):1439-42
GlcNalpha1-6-myo-inositol-1-HPO4-sn-1, 2-dipalmitoylglycerol  0   *Glycolipids Inositol/*analogs & derivatives Mannosyltransferases. Biochemistry. 2000 Sep 26;39(38) :11801-7
Amino-Cerv  0   *Urea *Inositol *Methionine Vaginal Creams, Foams, and Jellies. J Report Med 1999 Mar;44(3):275-8
3'-(1-chloroethyl)-2,3-dihydro-1H-imidazo(2,1-i)purine-4-ium-7-yl-3'-deoxy-1',5',6'-tri-O-(methylsulfonyl)-muco-inositol chloride  0   *Purines Inositol/*analogs & derivatives. Tumour Biol 1994;15(6):354-60
1,3,5-triamino-1,3,5-trideoxy-inositol  0   Inositol/*analogs & derivatives. Bioconjug Chem 1998 Nov-Dec;9(6):691-702
galactosylononitol  0   *Galactose *Inositol. Plant Physiol 1998 May;117(1):165-72
VP 602L  0   *Phosphonic Acids Inositol/*analogs & derivatives. Biochem Biophys Res Comm 1998 Mar 27;244(3):873-6
voglibose  83480-29-9   Inositol/*analogs & derivatives alpha-Glucosidases/antagonists & inhibitors.
Pharma Action Hypoglycemic Agents 		J Int Med Res 1995 Nov-Dec;23(6):497-501
glucosaminyl(1-6)inositol  0   Inositol/*analogs & derivatives. Biochemistry 1996 Jul 23;35(29):9496-504
VP 616L  0   *Phosphonic Acids Inositol/*analogs & derivatives Type C Phospholipases/antagonists & inhibitors. J Biol Chem 1996 Jun 28;271(26):15468-77
2,3-4,5-bis-O-(tetraisopropyldisiloxane-1,3-diyl)inositol  0   *Siloxanes Inositol/*analogs & derivatives. Carbohydr Res 1995 Jan 17;266(2):301-7
3-azido-3-deoxy-myo-inositol  52432-16-3   Inositol/*analogs & derivatives. Cancer Chemother Pharmacol 1994;35(1):71-9
3,6-di-O-benzyl-1,2-O-isopropylideneinositol  0   Inositol/*analogs & derivatives. Carbohydr Res 1994 Sep 1;262(1):59-77
1,2-3,4-di-O-cyclohexylidene-myo-inositol  0   Inositol/*analogs & derivatives. Bioorg Med Chem 1993 Aug;1(2):155-9
1,2-5,6-di-O-cyclohexylidene-myo-inositol  0   Inositol/*analogs & derivatives. Bioorg Med Chem 1993 Aug;1(2):155-9
mycothiol  0   *Cysteine *Glycopeptides *Inositol Mycobacterium. Eur J Biochem 1994 Aug 15;224(1):203-13
bromoconduritol-B-epoxide  24579-86-0   *Epoxy Compounds Inositol/*analogs & derivatives Glucosylceramidase/antagonists & inhibitors. J Lipid Res 1994 May;35(5):905-12
2,3-O-cyclohexylidene-myo-inositol  22144-55-4   Inositol/*analogs & derivatives. Carbohydr Res 1994 Mar 18;256(1):49-58
3-deoxy-3-C-(phosphonomethyl)inositol  0   *Organophosphorus Compounds Inositol/*analogs & derivatives. Carbohydr Res 1993 Dec 28;250(2):315-21
proheparum  72980-85-9   *Cysteine *Inositol *Liver Extracts *Bis-Trimethylammonium Compounds *Vitamin B 12 Drug Combinations. Nippon Shokakibyo Gakkai Zasshi 1993 Nov;90(11):2945-50
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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