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Hyaluronoglucosaminidase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS.      Other names Hyaluronidase; Permeability Factor, Duran-Reynals; Hydrolase, Hyaluronate; Factor, Duran-Reynals Permeability; Duran Reynals Permeability Factor; Wydase; Hyaluronate Hydrolase; Hyaglosidase; GL Enzyme; Duran-Reynals Permeability FactorDrugs* : VITRASE; AMPHADASE; HYDASE; HYLENEX RECOMBINANT; WYDASE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
BmHYA1 protein, Buthus martensi  EC 3.2.1.35   *Hyaluronoglucosaminidase *Scorpion Venoms. Comp Biochem Physiol C Toxicol Pharmacol 2008 Sep;148(3):250-7
Hyalp1 protein, mouse  EC 3.2.1.35   *Hyaluronoglucosaminidase. J Androl 2007 Jan-Feb;28(1):67-76
Hyal5 protein, mouse  EC 3.2.1.35   *Hyaluronoglucosaminidase. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50); 18028-33
Api m 2 allergen, Apis mellifera  EC 3.2.1.35   *Hyaluronoglucosaminidase *Antigens, Plant Bee Venoms. J Allergy Clin Immunol 2005 Feb;115(2):323-9
Hyal2 protein, human  EC 3.2.1.25   *Hyaluronoglucosaminidase *Cell Adhesion Molecules GPI-Linked Proteins Receptors, Virus. Curr Top Microbiol Immunol 2003;275:179-99
Hyal2 protein, mouse  EC 3.2.1.35   *Hyaluronoglucosaminidase GPI-Linked Proteins. BMC Cell Biol 2002 Apr 3;3(1):8
Hyal1 protein, mouse  EC 3.2.1.35   *Hyaluronoglucosaminidase. BMC Cell Biol 2002 Apr 3;3(1):8
Hyal2 protein, Xenopus  EC 3.2.1.25   *Hyaluronoglucosaminidase *Xenopus Proteins. Mech Dev 2002 Feb;111(1-2):25-35
MGEA5 protein, human  EC 3.2.1.52   *Antigens, Neoplasm *Hyaluronoglucosaminidase *Histone Acetyltransferases Antigens, Neoplasm Meningioma. Hum Mol Genet 1998 Nov;7(12):1859-72
allergen Ves v 2  EC 3.2.1.-   *Hyaluronoglucosaminidase *Wasp Venoms Allergens. J Allergy Clin Immunol 1996 Sep;98(3):588-600
allergen Ves v 1  EC 3.2.1.35   *Hyaluronoglucosaminidase *Insect Proteins *Antigens, Plant Wasp Venoms. J Allergy Clin Immunol 1996 Sep;98(3):588-600
hyaluronidase PH-20  EC 3.2.1.35   *Hyaluronoglucosaminidase *Cell Adhesion Molecules Antigens, Surface. J Cell Biol 1990;11(6 Pt 2):2939
inter-alpha-inhibitor  39346-44-6 Trypsin inhibitor, inter-alpha  *Alpha-Globulins Hyaluronoglucosaminidase/antagonists & inhibitors.
Pharma Action Trypsin Inhibitors ; Serine Proteinase Inhibitors 		Alpha-1-Antitrypsin & Pi System WH400 A4563:157;1975; Am J Obstet Gynecol 129(6):633;1977; Fertil Steril 27(5):577;1976; Hoppe Seylers Z Physiol Chem 1979;360(9):1297; Hoppe Seylers Z Physiol Chem 1979;360(9):1305; Hoppe Seylers Z Physiol Chem 1979;360(9):1313; Hoppe Seylers Z Physiol Chem 357(3):487;1976; Hoppe-Seylers Z Physiol Chem 1979;360(9):1285; Methods Enzymol 45(B):760;1976; Nippon Kyobu Shikkan Gakkai Zasshi 1979;17(10):677; Thrombosis Res 13(3):563;1978
lidase  EC 3.2.1.-   *Hyaluronoglucosaminidase. Ann Neurol 6(1):78;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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