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Histone Acetyltransferases

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Definition: Enzymes that catalyze acyl group transfer from ACETYL-CoA to HISTONES forming CoA and acetyl-histones.     
Examples CLOCK Proteins; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivator 3 		Other names Acetyltransferases, Histone; Acetyltransferase, Histone; Acetylase, Histone; Histone Acetyltransferase; Histone Acetylase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MSL1 protein, mouse  EC 2.3.1.48   *Histone Acetyltransferases. Nat Struct Mol Biol 2011 Feb;18(2):142-9
Gcn5 protein, rat  EC 2.3.1.48   *Histone Acetyltransferases. Mol Cell Biochem 2010 Dec;345(1-2):309-16
Sgf29 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 Aug 1;66(Pt 8):902-4
Patt1 protein, human  EC 2.3.1.48.-   *Histone Acetyltransferases. Int J Biochem Cell Biol. 2009 Dec;41(12): 2528-37
MSL1 protein, human  EC 2.3.1.48   *Histone Acetyltransferases DNA Repair Protein Subunits. J Cell Physiol 2009 Dec;221(3):594-602
ELP3 protein, zebrafish  EC 2.3.1.48   *Nerve Tissue Proteins *Histone Acetyltransferases. Hum Mol Genet 2009 Feb 1;18(3):472-81
ELP3 protein, Drosophila  EC 2.3.1.48   *Nerve Tissue Proteins *Histone Acetyltransferases. Hum Mol Genet 2009 Feb 1;18(3):472-81
ELP3 protein, human  EC 2.3.1.48   *Nerve Tissue Proteins *Histone Acetyltransferases. Hum Mol Genet 2009 Feb 1;18(3):472-81
Eaf1 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Mol Cell Biol 2008 Apr;28(7):2257-70
SAS3 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Genome Biol 2007;8(6):R119
Elp3 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Biochem J 2008 Feb 1;409(3):779-88
MOF protein, mouse  EC 2.3.1.48   *Histone Acetyltransferases. Mol Cell Biol 2008 Jan;28(1):397-409
Hbo1 protein, mouse  EC 2.3.1.48   *Histone Acetyltransferases. Mol Cell Biol 2008 Jan;28(1):140-53
Rtt109 protein, S pombe  EC 2.3.1.48   *Schizosaccharomyces pombe Proteins *Histone Acetyltransferases. J Biol Chem Sep 28;292(39):28587-96
Tip60 protein, mouse  EC 2.3.1.-   *Trans-Activators *Histone Acetyltransferases. Nature 2007 Aug 30;448(7157):1063-7
SGF29 protein, rat  EC 2.3.1.48   *Histone Acetyltransferases. Oncogene 2007 Aug 16;26(38):5626-34
MOZ protein, rat  EC 2.3.1.48   *Histone Acetyltransferases. Biochem J 2007 Mar 15;402(3):559-66
Rtt109 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Science 2007 Feb 2;315(5812):649-52
At1g77540 protein, Arabidopsis  EC 2.3.1.48   *Histone Acetyltransferases. Biochemistry 2006 Dec 5;45(48):14325-36
Sgf73 protein, S cerevisiae  EC 2.3.1.48   *Histone Acetyltransferases Protein Subunits. Proc Natl Acad Sci U S A 2005 Jun 14;102(24):8478-82
Moz protein, zebrafish  EC 2.3.1.48   *Zebrafish Proteins *Histone Acetyltransferases Zinc Fingers. Development 2004 May;131(10):2443-61
MOZ protein, mouse  EC 2.3.1.48   *Histone Acetyltransferases Zinc Fingers. Genes Dev 2006 May 15;20(10):1321-30
Tip60 protein, Drosophila  EC 2.3.1.48   *Drosophila Proteins *Histone Acetyltransferases. Mol Cell Biol 2006 Mar;26(6):2347-59
Hbo1 protein, Xenopus  EC 2.3.1.48   *Xenopus Proteins *Histone Acetyltransferases. Mol Cell Biol 2006 Feb;26(3):1098-108
NuA4 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Mol Cell Biol 2005 Sep;25(18):8179-90
Swc4 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Eukaryot Cell. 2004 Aug;3(4):976-83
ELO3 protein, Arabidopsis  EC 2.3.1.48   *Arabidopsis Proteins *Histone Acetyltransferases. Proc Natl Acad Sci U S A 2005 May 24;102(21):7754-9
GCN5 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases.
KAT2A protein, human  EC 2.3.1.48   *Histone Acetyltransferases.
Gcn5l2 protein, mouse  EC 2.3.1.48   *Histone Acetyltransferases.
Myst4 protein, mouse  EC 2.3.1.48   *Histone Acetyltransferases.
Kat7 protein, rat  EC 2.3.1.48   *Histone Acetyltransferases.
KAT7 protein, human  EC 2.3.1.48   *Histone Acetyltransferases.
KAT8 protein, human  EC 2.3.1.48   *Histone Acetyltransferases.
Esa1 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases.
TRA1 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases.
KAT6B protein, human  EC 2.3.1.48   *Histone Acetyltransferases. J Biol Chem 1999 Oct 1;274(40):28528-36
MYS-1 protein, C elegans  EC 2.3.1.48   *Caenorhabditis elegans Proteins *Histone Acetyltransferases. Dev Cell 2004 Apr;6(4):563-76
Tot1 protein, S cerevisiae  EC 2.3.1.48   *Peptide Elongation Factors *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Mol Microbiol 2003 Sep;49(5):1297-307
NAT4 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. J Biol Chem 2003 Oct 3;278(40):38109-12
YAF9 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Mol Cell Biol 2003 Sep;23(17):6086-102
GCN5 protein, Arabidopsis  EC 2.3.1.48   *Arabidopsis Proteins *Histone Acetyltransferases Transcription Factors. Nucleic Acids Res 2001 Apr 1;29(7):1524-33
dik protein, Drosophila  EC 2.3.1.48   *Drosophila Proteins *Histone Acetyltransferases. Mol Cell Biol 2003 Jan;23(1):306-21
ADA2 protein, Drosophila  EC 2.3.1.48   *Drosophila Proteins *Histone Acetyltransferases. Mol Cell Biol 2003 Jan;23(1):306-21
Pcaf protein, Drosophila  EC 2.3.1.48   *Drosophila Proteins *Histone Acetyltransferases. Mol Cell Biol 2003 Jan;23(1):306-21
Sas2 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Nat Genet 2002 Nov;32(3):370-7
Yng1 protein, S cerevisiae  EC 2.3.1.48   *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Mol Cell Biol 2002 Jul;22(14):5047-53
AHC1 protein, S cerevisiae  0   *Chromosomal Proteins, Non-Histone *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases Acetyltransferases Trans-Activators. Mol Cell Biol 1999 Oct;19(10):6621-31
GCN5 protein, Toxoplasma gondii  0   *Protozoan Proteins *Histone Acetyltransferases. Nucleic Acids Res 1999 Nov 15;27(22):4344-52
tGCN5 histone acetyltransferase  EC 2.3.1.48   *Histone Acetyltransferases. Nature 1999 Jul 1;400(6739):86-9
Taf1 protein, Drosophila  EC 2.3.1.48   *Drosophila Proteins *Transcription Factor TFIID *Histone Acetyltransferases. J Biol Chem 1998 Nov 27;273(48):32254-64
MGEA5 protein, human  EC 3.2.1.52   *Antigens, Neoplasm *Hyaluronoglucosaminidase *Histone Acetyltransferases Antigens, Neoplasm Meningioma. Hum Mol Genet 1998 Nov;7(12):1859-72
CBP-1 protein, C elegans  EC 2.3.1.48   *Transcription Factors *Caenorhabditis elegans Proteins *Histone Acetyltransferases. Genes Dev 1998 Apr 1;12(7):943-55
mof protein, Drosophila  EC 2.3.1.-   *Nuclear Proteins *Drosophila Proteins *Histone Acetyltransferases Dosage Compensation, Genetic. EMBO J 1997 Apr 15;16(8):2054-60
histone acetyltransferase type B complex  EC 2.3.1.48   *Histone Acetyltransferases. Curr Biol 1998 Jan 15;8(2):96-108
hexosaminidase C  EC 3.2.1.50   *beta-N-Acetylhexosaminidases Histone Acetyltransferases. J Biol Chem 1998 Feb 6;273(6):3611-7
KAT6A protein, human  EC 2.3.1.48   *Histone Acetyltransferases Zinc Fingers. Nat Genet 1996 Sep;14(1):33-41
KAT5 protein, human  EC 2.3.1.-   *Histone Acetyltransferases. Virology 1996 Feb 15;216(2):357-66
SPT10 protein, S cerevisiae  EC 2.3.1.48   *Transcription Factors *Saccharomyces cerevisiae Proteins *Histone Acetyltransferases. Genetics 1994 Jan;136(1):93-105

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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