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Hypoxanthines

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Definition: Purine bases related to hypoxanthine, an intermediate product of uric acid synthesis and a breakdown product of adenine catabolism.  do not confuse with the specific chem HYPOXANTHINE; hypoxanthine riboside, hypoxanthine ribonucleoside   
Examples Guanine; Hypoxanthine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N1-3-fluorophenyl-hypoxanthine  0   *Hypoxanthines. Antiviral Res 2009 Jul;83(1):80-5
1-(hypoxanth-1-yl)-4-(guan-7-yl)-2,3-butanediol  0   *Butylene Glycols *Hypoxanthines. Chem Res Toxicol. 2007 Feb;20(2):284-9
9-methylhypoxanthine  0   *Hypoxanthines. Biophys Chem 2006 Jul 20;122(2):123-35
1-((8-aza-9-deazahypoxanthin-9-yl)methyl)-3-hydroxy-4-hydroxymethylpyrrolidine  0   *Hypoxanthines *Pyrrolidines Purine-Nucleoside Phosphorylase/antagonists & inhibitors. J Med Chem 2003 Nov 20;46(24):5271-6
1-((9-deazahypoxanthin-9-yl)methyl)-3-hydroxy-4-hydroxymethylpyrrolidine  0   *Hypoxanthines *Pyrrolidines Purine-Nucleoside Phosphorylase/antagonists & inhibitors. J Med Chem 2003 Nov 20;46(24):5271-6
8-hexylthio-hypoxanthine  0   *Hypoxanthines. Farmaco 2001 Nov;56(11):809-13
9-(6-hydroxymethyl-1-oxa-4-thiacyclohexan-2-yl)hypoxanthine  0   *Hypoxanthines *Nucleosides. Acta Crystallogr C 2001 May;57(Pt 5):560-1
1,9-dimethylhypoxanthine  0   *Hypoxanthines. J Nat Prod 2000 Feb;63(2):261-2
2-hydrazinohypoxanthine  0   *Hydrazines *Hypoxanthines. Chem Res Toxicol 1998 Dec;11(12):1453-9
2-chlorohypoxanthine  13368-14-4   *Hypoxanthines. J Bacteriol 1997 Feb;179(4):1385-92
4-((3-(1,6-dihyro-6-oxo-9H-purin-9-yl)-1-oxopropyl)amino)benzoic acid  138117-50-7   *Aminobenzoic Acids *Hypoxanthines. J Gerontol 1994 Mar;49(2):B51-3
9-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)hypoxanthine  149819-61-4   *Hypoxanthines. J Med Chem 1993 Sep 3;36(18):2627-38
ST 689  150679-43-9 ST 689  *Hypoxanthines. Ann N Y Acad Sci 1993 Jun 23;685:344-6
hypoxanthine 7-N-oxide  118974-81-5   *Cyclic N-Oxides *Hypoxanthines. Chem Pharm Bull (Tokyo) 1992 Mar;40(3):612-6
8-amino-3-benzylhypoxanthine  139460-96-1   *Hypoxanthines Purine-Nucleoside Phosphorylase/antagonists & inhibitors. J Med Chem 1992 Apr 17;35(8):1451-7
RM 06  126869-52-1   *Dipeptides *Hypoxanthines. J Chromatogr 1990;525(2):471
PCF 39  104317-64-8   *Hypoxanthines Arginine/*analogs & derivatives. Int J Immunopharmacol 1987;9(6):659
9-((2-methyl-4-methylene-5-oxotetrahydrofuran-2-yl)methyl)hypoxanthine  100682-44-8   *Hypoxanthines *Lactones. J Med Chem 1987;30(3):586
7,8-dihydrothiazole(3,2e)hypoxanthine  86870-52-2 Thiazolo(3,2-e)purin-4(1H)-one, 7,8-dihydro  *Hypoxanthines. Prog Clin Biol Res 1983;132E:273
9-(3,4-dioxopentyl)hypoxanthine  84182-19-4 2,3-Pentanedione, 5-(1,6-dihydro-6-oxo-9H-purin-9-yl)  *Hypoxanthines. Biochemistry 1982;21(25):6383
NPT 15392  76600-30-1 6H-Purin-6-one, 1,9-dihydro-9-(1-(1-hydroxyethyl)heptyl)-, (R*,S*)  *Hypoxanthines.
Pharma Action Adjuvants, Immunologic 		Clin Bull 1980;10(2):76
1-methylhypoxanthine  1125-39-9   *Hypoxanthines. Cancer Lett 1980;9(4):339
hypoxanthine 3-oxide  19765-65-2 1,7-dihydro-6H-purin-6-one 3-oxide  *Hypoxanthines. Cancer Res 38(8):2230;1978
2,4-diaminohypoxanthine  56-06-4   *Hypoxanthines GTP Cyclohydrolase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Neurochem Res 3(1):69;1978
2-azahypoxanthine  4656-86-4   *Hypoxanthines. Anal Biochem 88(2):612;1978; Cancer Res 36(8):2827;1976
4,5-diaminohypoxanthine  1672-50-0 4,5-diamino-6-hydroxypyrimidine  *Hypoxanthines. J Pharm Sci 63(4):622;1974
8-azahypoxanthine  2683-90-1   *Hypoxanthines. Exptl Cell Res. 69(1):92;1971

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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