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Isoleucine

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Definition: An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.  /biosyn /defic /physiol permitted    Other names L-Isomer Isoleucine; Isoleucine, L Isomer; L-Isoleucine; Isoleucine, L-Isomer; Alloisoleucine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
beta-methylisoleucine  0   Isoleucine/*analogs & derivatives. Org Lett 2010 Mar 19;12(6):1256-9
N-acetyl-2-amino-3-methylpentanoic acid  0   Isoleucine/*analogs & derivatives. Biosci Biotechnol Biochem 2009 Oct;73(10):2293-8
(S)-4-chlorophenylsulfonyl isoleucinol  0   Isoleucine/*analogs & derivatives. Bioorg Med Chem Lett. 2009 Feb 1;19(3):926-9
jasmonoyl-isoleucine  0   *Cyclopentanes Isoleucine/*analogs & derivatives. Nature 2007 Aug 9;448(7154):661-5
N-((1-oxoindan-4-yl)carbonyl)isoleucine methyl ester  0   *Indans Isoleucine/*analogs & derivatives. J Exp Bot 2007;58(15-16):4071-82
UAMC00132  0   *Indoles Isoleucine/*analogs & derivatives. J Leukoc Biol 2007 May;81(5);1252-7
2-amino-3-methylpentanoic acid  0   Isoleucine/*analogs & derivatives. Acta Crystallogr B 2000 Aug;56(Pt 4):720-7
sodium N-(4-n-dodecyloxybenzoyl)-L-isoleucinate  0   *Benzoates Isoleucine/*analogs & derivatives. J Chromatogr A. 2006 Sep 22;1128(1-2):259-66
(2S,3S,4R)-gamma-hydroxyisoleucine  0   Isoleucine/*analogs & derivatives. Org Biomol Chem. 2004 Mar 21;2(6):808-9
(2S,3S)-3'-fluoroisoleucine  0   Isoleucine/*analogs & derivatives. Org Biomol Chem. 2004 Mar 7;2(5):797-802
poly(N-undecenoxycarbonylisoleucinate)  0   *Polymers Isoleucine/*analogs & derivatives. Electrophoresis 2004 Mar;25(6):853-60
coronalon  0   Isoleucine/*analogs & derivatives. FEBS Lett. 2004 Apr 9;563(1-3):17-22
2-cyano-1-isoleucylpyrrolidine  0   *Pyrrolidines Isoleucine/*analogs & derivatives. Adv Exp Med Biol 2003;524:155-63
2,2'-dithio(N-isoleucylbenzamide)  0   *Benzamides Isoleucine/*analogs & derivatives Zinc Fingers. J Pharm Biomed Anal 2000 Aug 15;23(2-3):395-402
WF 14865B  0   *Epoxy Compounds Isoleucine/*analogs & derivatives Cathepsin B/antagonists & inhibitors. J Antibiot (Tokyo) 2000 May;53(5):449-58
WF 14865A  0   *Epoxy Compounds Isoleucine/*analogs & derivatives Cathepsin B/antagonists & inhibitors. J Antibiot (Tokyo) 2000 May;53(5):449-58
isoleucyl-thiazolidide  0   *Thiazoles Isoleucine/*analogs & derivatives. Diabetes 1998 Aug;47(8):1253-8
4-hydroxyisoleucine  0   Isoleucine/*analogs & derivatives. Phytochemistry 1997 Feb;44(4):563-6
P 9941  0   Isoleucine/*analogs & derivatives. Nat Struct Biol 1995 Apr;2(4):274-80
tert-butyloxycarbonyl(alloisoleucylisoleucyl)3 methyl ester  0   *Oligopeptides Isoleucine/*analogs & derivatives. Int J Pept Protein Res 1995 Feb;45(2):100-5
isoleucinomycin  65230-09-3   Isoleucine/analogs & derivatives Peptides, Cyclic. Acta Crystallogr A 1995 Jan 1;51(Pt 1):81-7
isoleucine methyl ester  2577-46-0   Isoleucine/*analogs & derivatives. Parasitology 1987;95 (Pt 1):31
technetium Tc 99m Sn-thioglycolic acid-isoleucine complex  0   *Isoleucine *Thioglycolates *Organotechnetium Compounds. JPMA 1986;36(2):40
isoleucylhydroxamic acid  31982-77-1   Isoleucine/*analogs & derivatives. J Bacteriol 1980;144(1):291
technetium Tc 99m (Sn)pyridoxylideneisoleucine  0   *Organotechnetium Compounds Isoleucine/*analogs & derivatives. J Nucl Med 1979;20(11):1189
technetium Tc 99m pyridoxylideneisoleucine  0   *Organotechnetium Compounds Isoleucine/*analogs & derivatives. Am J Gastroenterol 1979;72(6):630; Clin Nucl Med 4(8):325;1979; Kaka Igaku 16(2):147;1979; Kaku Igaku 14(6):927;1978; Kaku Igaku 15(5):721;1978; Kaku Igaku 15(8):1125;1978; Kaku Igaku 15(8):1197;1978; Kaku Igaku 16(5):795;1979; Nippon Igaku Hoshasen Gakkai Zasshi 39(2):132;1979; Nippon Shokakibyo Gakkai Zasshi 76(4):924;1979; Nippon Shokakibyo Gakkai Zasshi 76(6):1315;1979; Radioisotopes 27(10):609;1978; Radioisotopes 27(12):734;1978; Radioisotopes 27(3):153;1978; Radioisotopes 27(3):157;1978
isoleucinol  4379-13-9 2-amino-3-methyl-1-pentanol  Isoleucine/*analogs & derivatives. Eur J Biochem 71(2):437;1976
isoleucylbromomethyl ketone  59079-43-5 2-Hexanone, 3-amino-1-bromo-4-methyl-, hydrobromide, (S-(R*,R*))  Isoleucine/*analogs & derivatives. Eur J Biochem 63(2):419;1976; Eur J Biochem 78(1):239;1977
isoleucine tetrazole  56943-00-1 1H-Tetrazole-5-methanamine, alpha-(1-methylpropyl)-, (S-(R*,R*))  Isoleucine/*analogs & derivatives. J Bacteriol 123(3):862;1975
4-thiaisoleucine  443-80-1   Isoleucine/*analogs & derivatives. J Bacteriol 116(2):564;1973
N-ethylcarbaminomethyl-L-isoleucine  54805-04-8 N-(((ethoxycarbonyl)amino)methyl)-L-isoleucine  Isoleucine/*analogs & derivatives. Gan 66(1):29;1975; Jpn J Pharmacol (Suppl) 24:35;1974; Nippon Yakurigaku Zasshi 75(1):53;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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