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Macrophages

More information in Books or onNLM PubMed
Definition: The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)     
See Also Phagocytosis
Examples Epithelioid Cells; Foam Cells; Giant Cells, Foreign-Body; Giant Cells, Langhans; Histiocytes; Kupffer Cells; Macrophages, Alveolar; Macrophages, Peritoneal; Osteoclasts 		Other names Monocyte-Derived Macrophages; Bone Marrow-Derived Macrophages; Monocyte-Derived Macrophage; Monocyte Derived Macrophages; Macrophages, Monocyte Derived; Macrophages, Bone Marrow-Derived; Macrophage, Monocyte-Derived; Macrophage, Bone Marrow-Derived; Bone Marrow-Derived Macrophage; Bone Marrow Derived Macrophages; Macrophages, Monocyte-Derived; Macrophage
 
SubstanceCAS Registry & nameCategoriesSource
MARCO protein, rat  0   *Receptors, Immunologic Macrophages. J Neuroinflammation. 2011;8(1) (dup#15):11
MARCO protein, human  0   *Receptors, Immunologic Macrophages.
Pstpip2 protein, mouse  0   *Cytoskeletal Proteins *Adaptor Proteins, Signal Transducing Macrophages.
Atf3 protein, mouse  0   *Activating Transcription Factor 3 Lipopolysaccharides Macrophages. Mol Immunol 1996 Aug;33(11-12):989-98
IT 174  0   *Furans Macrophages. Transplant Proc 1995 Feb;27(1):564-5
Marco protein, mouse  0   *Receptors, Immunologic Macrophages. Cell 1995 Feb 24;80(4):603-9
RON protein  EC 2.7.1.-   *Receptor Protein-Tyrosine Kinases Macrophages Hepatocyte Growth Factor. Oncogene 1993 May;8(5):1195-1202
CD68 antigen, human  0   *Antigens, Differentiation, Myelomonocytic *Antigens, CD Macrophages. Int Immunol 1990;2(10):973
macrophage procoagulant activity  0   *Blood Coagulation Factors Lymphocytes Macrophages Monocytes. Prog Hemost Thromb 1984;7:183
alveolar macrophage growth factor  0   *Peptides Macrophages. Am Rev Respir Dis 1984;130(3):450
Mac-120 antigen, human  0   *Antigens, Differentiation, Myelomonocytic Chromosomes, Human, Pair 11 Macrophages/immunology Monocytes/immunology. J Invest Dermatol 1984;83(1):48
antimacrophage globulin  0   *Immune Sera Immunization, Passive Macrophages. Transplantation 1981;31(4):299
macrophage surface glycoprotein GP160  0   *Membrane Glycoproteins Macrophages. J Exp Med 1980;152(6):1699

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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