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Lipopolysaccharides

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Definition: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)  coordinate IM with specific bacterium (IM) if pertinent; DF: LPS    Other names Lipoglycans
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-hydroxy-2,6-dimethoxyphenyl-6'-O-vanilloyl-beta-D-glucopyranoside  0   *Lipopolysaccharides. Planta Med. 2010 Jul;76(10):1007-10
4-hydroxy-2,6-dimethoxyphenyl-6'-O-syringoyl-beta-D-glucopyranoside  0   *Lipopolysaccharides. Planta Med. 2010 Jul;76(10):1007-10
CIA07 adjuvant  0   *DNA, Bacterial *Lipopolysaccharides Cancer Vaccines. Vaccine 2006 Jul 26;24(31-32):5862-71
lipopolysaccharide IP-PA1, Pantoea agglomerans  0   *Lipopolysaccharides. Eur Cytokine Netw 1992 Jul-Aug;3(4):417-20
Kdo2-lipid A  0   *Lipopolysaccharides. Prostaglandins Other Lipid Mediat 2005 Sep;77(1-4):131-40
axinelloside A  0   *Lipopolysaccharides. J Am Chem Soc. 2005 Sep 28;127(38):13262-70
lipopolysaccharide-6B, Yersinia pestis  0   *Lipopolysaccharides. Carbohydr Res 2005 Jul 4;340(9):1625-30
lipopolysaccharide-6A, Yersinia pestis  0   *Lipopolysaccharides. Carbohydr Res 2005 Jul 4;340(9):1625-30
lipopolysaccharide, Helicobacter pylori serotype O2  0   *Lipopolysaccharides. Carbohydr Res 2005 Jul 4;340(9):1605-11
Lrba protein, mouse  EC 2.7.10.-   *Adaptor Proteins, Signal Transducing Lipopolysaccharides.
heptadepsin, Paenibacillus  0   *Depsipeptides Lipopolysaccharides/antagonists & inhibitors. Chem Biol 2004 Aug;11(8):1059-70
CXorf40A protein, human  0   *Membrane Proteins Lipopolysaccharides. Biochem Biophys Res Commun. 2004 Dec 17;325(3):798-802
Protollin  0   *Cysteine Endopeptidases *Lipopolysaccharides Drug Combinations. Vaccine 2004 Sep 9;22(27-28):3691-7
lipopolysaccharide, E coli J5  0   *Lipopolysaccharides Meningococcal Vaccines. Vaccine 2003 Nov 7;21(31):4576-87
lipopolysaccharide, E coli O55-B5  0   *Lipopolysaccharides. Arterioscler Thromb Vasc Biol 2003 May 1;23(5):905-10
Nod factor, Rhizobium giardinii  0   *Lipopolysaccharides. Carbohydr Res. 2003 Jan 31;338(3):237-50
lipopolysaccharide, Helicobacter pylori  0   *Lipopolysaccharides. J Med Invest 2001 Aug;48(3-4):167-74
lipopolysaccharide, Escherichia coli 0111 B4  0   *Lipopolysaccharides Escherichia coli. Vox Sang 2001;80(3):170-8
CE3 lipopolysaccharide  0   *Lipopolysaccharides. J Bacteriol 2001 Oct;183(20):6054-64
alphaKdo(2-4)alphaKdo(2-4)alphaKdo(Kdo, 3-deoxy-D-manno-oct-2-ulopyranosonic acid)  0   *Trisaccharides Lipopolysaccharides. J Endotoxin Res. 2000;6(5):361-8
lipopolysaccharide, E. coli 026-B6  0   *Lipopolysaccharides. Rev Argent Microbiol 2001 Jan-Mar;33(1):28-35
lipopolysaccharide, Proteus  0   *Lipopolysaccharides. Carbohydr Res 2001 Feb 28;330(4):537-40
LRBA protein, human  EC 2.7.10.-   *Adaptor Proteins, Signal Transducing Lipopolysaccharides. J Immunol 2001 Apr 1;166(7):4586-95
Nod factor , Azorhizobium caulinodans  0   *Lipopolysaccharides. J Biol Chem 2000 May 26;275(21):15676-84
SAEP-4 peptide  0   *Oligopeptides Lipopolysaccharides/antagonists & inhibitors. Infect Immun 2000 Mar;68(3):1655-63
SAEP-2 peptide  0   *Peptides, Cyclic Lipopolysaccharides/antagonists & inhibitors. Infect Immun 2000 Mar;68(3):1655-63
E5564  0   Lipid A/*analogs & derivatives Lipopolysaccharides/antagonists & inhibitors. J Chromatogr B Biomed Sci Appl 1999 Dec 24;736(1-2):67-75
PCM 1207 lipopolysaccharide  0   *Lipopolysaccharides. Eur J Biochem 1999 Nov;266(1):53-61
OM 174 lipid  0   *Lipopolysaccharides Lipid A.
B 1287  0   *Lipopolysaccharides Lipid A/antagonists & inhibitors. J Immunol 1998 Nov 15;161(10):5413-20
K-12 lipopolysaccharide  0   *Lipopolysaccharides. J Bacteriol 1998 Oct;180(20):5313-8
5,7-diacetamido-8-O-acetyl-3,5,7,9-tetradeoxy-glycero-talo-nonulosonic acid  0   *Sialic Acids Acetyltransferases Lipopolysaccharides. Carbohydr Res 1997 Oct 28;304(1):77-9
monofucosyl A type 1  0   *Lipopolysaccharides Antigens, Bacterial. FEMS Microbiol Lett 1997 Sep 1;154(1):103-9
Atf3 protein, mouse  0   *Activating Transcription Factor 3 Lipopolysaccharides Macrophages. Mol Immunol 1996 Aug;33(11-12):989-98
Nod factor, Rhizobium leguminosarum  0   *Lipopolysaccharides. Microbiology 1995 Mar 21;34(11):3832-40
Nod factor, Rhizobium etli  0   *Lipopolysaccharides. J Biol Chem 1995 Mar 17;270(11):6050-5
Nod factor IV, Rhizobium meliloti  0   *Lipopolysaccharides. Biochem J 1995 Feb 15;306(Pt 1):259-64
Nod factor V, Bradyrhizobium japonicum  163181-91-7   *Lipopolysaccharides. Glycoconj J 1994 Jun;11(3):257-61
Nod factor IV, Bradyrhizobium japonicum  0   *Lipopolysaccharides. Glycoconj J 1994 Jun;11(3):257-61
J-5 lipopolysaccharide  0   *Lipopolysaccharides. Eur J Biochem 1994 Sep 1;224(2):751-60
Re lipopolysaccharide  0   *Lipopolysaccharides. J Biol Chem 1994 Jan 21;269(3):2241-4
pertussis endotoxin  0   *Lipopolysaccharides *Virulence Factors, Bordetella Antigens, Bacterial Bordetella pertussis. Springer Semin Immunopathol 1993;15(2-3):205-15
O19 antigen, Xanthomonas maltophilia  0   *Lipopolysaccharides Xanthomonas. Carbohydr Res 1993 Sep 2;247:249-54
lipopolysaccharide A  0   *Lipopolysaccharides. Mol Microbiol 1993 May;8(4):771-82
allyl 6-O-(3-deoxyoct-2-ulopyranosylonic acid)-(1-6)-2-deoxy-2-(3-hydroxytetradecanamido)glucopyranoside 4-phosphate  142235-84-5   *Disaccharides Lipopolysaccharides. Carbohydr Res 1992 Apr 10;228(1):37-45
F62 lipooligosaccharide  0   *Lipopolysaccharides Neisseria gonorrhoeae. Mol Immunol 1991;28(11):1233
CAP18 lipopolysaccharide-binding protein  143108-26-3   *Antimicrobial Cationic Peptides Multigene Family Lipopolysaccharides. Biochem Biophys Res Commun 1991;179(1):170
FEV1 lipopolysaccharide  0   *Lipopolysaccharides Fusobacterium. FEMS Microbiol Immunol 1991;3(1):47
lipomannan  0   *Lipopolysaccharides. J Biol Chem 1990;265(16):9272
Pyrifer  59392-65-3   *Lipopolysaccharides. Cesk Neurol Neurochir 1989;53(3):193
lipopolysaccharide-binding protein  0   *Acute-Phase Proteins *Carrier Proteins *Membrane Glycoproteins Lipopolysaccharides. J Exp Med 1989;170(4):1231
A antigen (Brucella abortus)  0   *Lipopolysaccharides Epitopes. Can J Microbiol 1987;33(11):979
deacylated lipopolysaccharides  0   *Lipopolysaccharides. J Exp Med 1987;165(5):1393
lipoarabinomannan  0   *Lipopolysaccharides Antigens, Bacterial Mycobacterium. J Biol Chem 1986;261(26):12345
trinitrophenyl-lipopolysaccharide  0   *Lipopolysaccharides Antigens, T-Independent Endotoxins Escherichia coli Haptens Trinitrobenzenes. Toxicol Appl Pharmacol 1986;83(3):456
2-(4-azidosalicylamido)-1,3'-dithiopropionate-lipopolysaccharide  0   *Azides *Lipopolysaccharides. J Biol Chem 1985; 260(28):15068
lipopolysaccharide II, Yersinia pestis  0   *Lipopolysaccharides Yersinia pestis. Eur J Biochem 1985;151(2):399
lipopolysaccharide I, Yersinia pestis  0   *Lipopolysaccharides Yersinia pestis. Eur J Biochem 1985;151(2):399
endotoxin, Escherichia coli  67924-63-4   *Endotoxins Escherichia coli Lipopolysaccharides. Infect Immun 1984;47(1):329
Klebsiella O3 lipopolysaccharide  0   *Lipopolysaccharides Klebsiella pneumoniae. Jpn J Pharmacol 1984;36(1):51
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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