encyclopedia of medical concepts
ψ 

Oxidoreductases, N-Demethylating

More information in Books or onNLM PubMed
Definition:      
Examples Aminopyrine N-Demethylase; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Dihydropteridine Reductase; Dimethylglycine Dehydrogenase; Ethylmorphine-N-Demethylase; Histone Demethylases; Sarcosine Dehydrogenase; Sarcosine Oxidase 		Other names N-Demethylating Oxidoreductases; N Demethylating Oxidoreductases; N Demethylases; Demethylating Oxidoreductases, N; Oxidoreductases, N Demethylating; N-Demethylases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Jmjd2c protein, mouse  EC 1.5.-   *Oxidoreductases, N-Demethylating. Biochem Biophys Res Commun 2009 Nov 13;389(2):366-71
kdm1b protein, mouse  EC 1.5.-   *Oxidoreductases, N-Demethylating. Nature. 2009 Sep 17;461(7262):415-8
KDM2A protein, human  EC 1.5.-   *Oxidoreductases, N-Demethylating *F-Box Proteins. Cell Cycle. 2008 Nov 15;7(22):3539-47
Ndy1 protein, mouse  EC 1.5.-   *Oxidoreductases, N-Demethylating. Mol Cell Biol 2008 Dec;28(24):7451-64
Lsd1 protein, S pombe  EC 1.5.-   *Oxidoreductases, N-Demethylating *Schizosaccharomyces pombe Proteins. Cell 2008 Oct 17;135(2):272-83
Lid2 protein, S pombe  EC 1.5.-   *Oxidoreductases, N-Demethylating *Schizosaccharomyces pombe Proteins. Cell 2008 Oct 17;135(2):272-83
UTX protein, Drosophila  EC 1.5.-   *Oxidoreductases, N-Demethylating *Drosophila Proteins. Mol Cell Biol 2008 Feb;28(3):1041-6
Lsd1 protein, Drosophila  EC 1.5.-   *Oxidoreductases, N-Demethylating *Drosophila Proteins. Curr Biol 2007 May 1;17(9):808-12
JMJD1C protein, human  EC 1.14.11.-   *Oxidoreductases, N-Demethylating *Jumonji Domain-Containing Histone Demethylases. Arch Biochem Biophys 2007 Apr 1;460(1):56-66
Aof2 protein, mouse  EC 1.-   *Oxidoreductases, N-Demethylating. Nature. 2005 Sep 15;437(7057):436-9
cytochrome P-450 CYP3A65, zebrafish  EC 1.14.14.1   *Aryl Hydrocarbon Hydroxylases *Oxidoreductases, N-Demethylating *Zebrafish Proteins. Toxicol Appl Pharmacol 2005 Jun 15;205(3):247-58
Kdm5c protein, mouse  EC 1.5.-   *Oxidoreductases, N-Demethylating.
Cyp3a62 protein, rat  EC 1.14.14.1   *Aryl Hydrocarbon Hydroxylases *Oxidoreductases, N-Demethylating. J Pharmacol Exp Ther. 2004 Jun;309(3):1282-90
SPR-5 protein, C elegans  EC 1.5.-   *Oxidoreductases, N-Demethylating *Caenorhabditis elegans Proteins. EMBO J 2002 Nov 1;21(21):5787-96)
Cyp3a9 protein, rat  EC 1.14.14.1   *Aryl Hydrocarbon Hydroxylases *Oxidoreductases, N-Demethylating. Biochem Biophys Res Commun 1996 Apr 5;221(1):157-62
metflurazon-N-demethylase  EC 1.13.99.-   *Cytochrome P-450 Enzyme System *Oxidoreductases, N-Demethylating. Plant Physiol 1996 Sep;112(1):361-70
S-mephenytoin N-demethylase  EC 1.14.14.1   *Aryl Hydrocarbon Hydroxylases *Oxidoreductases, N-Demethylating. Drug Metab Dispos 1996 Sep;24(9):948-54
SolA protein, E coli  EC 1.-   *Oxidoreductases, N-Demethylating *Escherichia coli Proteins. Gene 1996 Nov 28;181(1-2):179-83
KDM5C protein, human  EC 1.5.-   *Oxidoreductases, N-Demethylating. Hum Mol Genet 1994 Jan;3(1):153-60
desipramine N-demethylase  EC 1.5.1.-   *Cytochrome P-450 Enzyme System *Oxidoreductases, N-Demethylating. Biol Pharm Bull 1993 Jun;16(6):571-5
reticuline oxidase  EC 1.5.3.9   *Oxidoreductases, N-Demethylating. Proc Natl Acad Sci USA 1991;88(22):9969
1,2-dimethylhydrazine demethylase  EC 1.5.-   *Cytochrome P-450 Enzyme System *Oxidoreductases, N-Demethylating. Cancer Lett 1991;59(3):225
tamoxifen N-demethylase  EC 1.5.3.-   *Cytochrome P-450 Enzyme System *Oxidoreductases, N-Demethylating. Biochem Pharmacol 1991;21(12):1911
diazepam N-demethylase  EC 1.5.-   *Cytochrome P-450 Enzyme System Oxidoreductases, N-Demethylating. Drug Metab Dispos 1990;18(5):812
imipramine demethylase  EC 1.5.1.-   *Cytochrome P-450 Enzyme System *Oxidoreductases, N-Demethylating. Pol J Pharmacol Pharm 1988;40(4):351
cocaine N-demethylase  EC 1.5.-   *Oxidoreductases, N-Demethylating. Life Sci 1988;42(1):79
stobadine N-demethylase  EC 1.5.-   *Oxidoreductases, N-Demethylating. J Chromatogr 1987;415(1):163
N-methyl-4-chloroanaline-N-demethylase  EC 1.5.1.-   *Oxidoreductases, N-Demethylating. Biochemistry 1986;25(16):4705
hexamethylphosphoramide N-demethylase  EC 1.5.1.-   *Oxidoreductases, N-Demethylating. Biochem Pharmacol 1985;34(5):631
4-chloro-N-methylaniline demethylase  EC 1.5.-   *Oxidoreductases, N-Demethylating. J Pharmacol Exp Ther 1981;217(3):572
diethylcarbamazine demethylase  EC 1.5.-   *Oxidoreductases, N-Demethylating. Indian J Exp Biol 1980;18(11):1298
meperidine N-demethylase  EC 1.5.99.-   *Oxidoreductases, N-Demethylating. J Pharmacol Exp Ther 1980;213(1):28
dimethylaminoantipyrine N-demethylase  EC 1.5.99.-   *Oxidoreductases, N-Demethylating. Chem Biol Interact 1980;29(3):277
trimethylamine dehydrogenase  EC 1.5.8.2   *Oxidoreductases, N-Demethylating. Biochem Biophys Res Commun 71(4):1289;1976; Biochem J 148:513;1975; Biochem J 169(2):361;1978; Biochim Biophys Acta 429(3):705;1976; Comp Biochem Physiol 44(2):357;1973; FEBS Lett 85(1):137;1978; J Biol Chem 253(12):4086;1978; J Biol Chem 253(8):2812;1978; J Biol Chem 254(8):2684;1979; Microbiol Rev 43(3):384;1979
tetramethylphenylenediamine oxidase  EC 1.5.99.-   *Oxidoreductases, N-Demethylating. Eur J Biochem 100(1):19;1979; J Bacteriol 128(1):144;1976; Vestn Akad Med Nauk SSSR 12:4;1974; Zentralbl Bakteriol 237(2-3):351;1977
morphine-N-demethylase  EC 1.5.-   *Oxidoreductases, N-Demethylating. Arzneim Forsch 25(3):365;1975; Biochem Biophys Res Commun 89(1):233;1979
3-methyl-4-methylaminoazobenzene-N-demethylase  EC 1.5.-   *Oxidoreductases, N-Demethylating. Proc Soc Exptl Biol Med 139(3):865;1972
N6-methyl-lysine oxidase  EC 1.5.3.4   *Oxidoreductases, N-Demethylating. Arch Biochem Biophys 165(1):369;1974
N-methylglutamate dehydrogenase  EC 1.5.99.5   *Oxidoreductases, N-Demethylating. Biochem J 161(2):357;1977; Biochem J 167(2):509;1977; Biochem Soc Trans 6(1):193;1978; Mikrobiologiia 44(3):552;1975
N-methylaniline N-demethylase  EC 1.5.-   *Oxidoreductases, N-Demethylating. Toxicol Appl Pharmacol 23(3):399;1972
N,N-dimethylaniline demethylase  EC 1.5.-   *Oxidoreductases, N-Demethylating. J Pharm Exp Therap 207(3):721;1978
dimethylamine dehydrogenase  EC 1.5.99.-   *Oxidoreductases, N-Demethylating. Biochem Biophys Res Commun 88(1):244;1979
4-chloro-N-methylaniline hydroxylase  EC 1.5.99.-   *Oxidoreductases, N-Demethylating Aniline Compounds. Anal Biochem 77(2):523;1977
chlorcyclizine N-demethylase  EC 1.5.99.-   *Oxidoreductases, N-Demethylating. J Pharmacol Exp Ther 82(2):314;1972
benzphetamine N-demethylase  EC 1.14.14.1   *Cytochrome P-450 Enzyme System *Oxidoreductases, N-Demethylating. Acta Biol Med Ger 1979;38(1):11; Arch Environ Health 34(6):400;1979; Biochem Biophys Res Commun 1979;91(3):747; Biochem Mol Biol Int 1995 Dec;37(6):1121-6; Biochem Pharmacol 25(19):2187;1976; Biochim Biophys Acta 509:326;1978; Cancer Res 34(9):2196;1974

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy