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Phosphoric Monoester Hydrolases

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Definition: A group of hydrolases which catalyze the hydrolysis of monophosphoric esters with the production of one mole of orthophosphate. EC 3.1.3.  DF: note short X ref   
Examples Acid Phosphatase; Alkaline Phosphatase; Fructose-Bisphosphatase; Glucose-6-Phosphatase; Histidinol-Phosphatase; 4-Nitrophenylphosphatase; Mitogen-Activated Protein Kinase Phosphatases; Nucleotidases; Phosphatidate Phosphatase; Phosphofructokinase-2; Phosphoprotein Phosphatases; 6-Phytase; Protein Tyrosine Phosphatases; PTEN Phosphohydrolase 		Other names Phosphomonoesterases; Phosphohydrolases; Phosphatases; Hydrolases, Phosphoric Monoester
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PECP1 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Biochim Biophys Acta. 2012 Feb;1824(2):319-25
PGAM5 protein, mouse  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. J Biol Chem. 2011 Dec 30;286(52):44542-56.
PRG-3 protein, rat  EC 3.1.3.-   *Phosphoric Monoester Hydrolases Nerve Tissue Proteins Biological Markers. Eur J Neurosci. 2004 Jan;19(1):212-20.
PTEN2b protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Biochem J. 2012 Jan 1;441(1):161-71.
PTEN2a protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Biochem J. 2012 Jan 1;441(1):161-71.
SSH3 protein, rat  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2424-31.
NDX-4 protein, C elegans  EC 3.1.6.-   *Phosphoric Monoester Hydrolases *Caenorhabditis elegans Proteins DNA Repair Enzymes. DNA Repair (Amst) 2011 Feb 7;10(2):176-87
NUDT2 protein, human  EC 3.6.1.-   *Phosphoric Monoester Hydrolases. Int J Cancer 2011 Apr 15;128(8):1770-82
SHIP2 protein, zebrafish  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Zebrafish Proteins. Dis Model Mech 2010 Nov-Dec;3(11-12):733-42
MTMR14 protein, mouse  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Nat Cell Biol 2009 Jun;11(6):769-76
VPA0450 protein, Vibrio parahaemolyticus  EC 3.1.3.25   *Bacterial Proteins *Phosphoric Monoester Hydrolases. Science. 2010 Sep 24;329(5999):1660-2
geraniol synthase, Perilla hirtella  EC 3.6.1.-   *Phosphoric Monoester Hydrolases. Phytochemistry 2010 Jul;71(10):1068-75
PHOSPHO1 protein, mouse  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. J Bone Miner Res 2010 Apr;25(4):716-23
plasticity-related gene 5 protein, mouse  EC 3.1.3.-   *Membrane Proteins *Phosphoric Monoester Hydrolases. Mol Biol Cell 2010 Feb;21(4):521-37
myotubulerin protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Signal Behav 2009 Nov;4(11):1049-58
DUF299 protein, E coli  0   *Multienzyme Complexes *Phosphoric Monoester Hydrolases *Protein Kinases. BMC Biochem 2010;11:1
Hint4 protein, Arabidopsis  EC 3.-   *Multienzyme Complexes *Phosphoric Monoester Hydrolases *Sulfatases. FEBS Lett 2010 Jan 4;584(1):93-8
lipid A 1-phosphatase, Porphyromonas gingivalis  EC 3.1.3.-   *Bacterial Proteins *Phosphoric Monoester Hydrolases Virulence Factors. Cell Microbiol 2009 Nov;11(11):1587-99
PHPT1 protein, mouse  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Ups J Med Sci 2009;114(2):65-72
Pps protein, mouse  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Mol Cell Biol 2008 Sep;28(17):5184-95
JAWS protein, mouse  EC 3.1.3.-   *Phosphoric Monoester Hydrolases Membrane Proteins. Development 2008 Jul;135(13):2215-20
SSH2 protein, rat  EC 3.1.3.-   *Microfilament Proteins *Phosphoric Monoester Hydrolases. J Biol Chem 2008 Mar 7;283(10):6013-21
SSH1 protein, rat  EC 3.1.3.-   *Microfilament Proteins *Phosphoric Monoester Hydrolases. J Biol Chem 2008 Mar 7;283(10):6013-21
Sac3 protein, rat  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Cell Res 2007 Nov;17(11):919-32
methyl parathion hydrolase, Sphingomonas  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. J Appl Microbiol 2007 Jun;102(6):1578-85
PGAP1 protein, mouse  EC 3.1.3.-   *Membrane Proteins *Phosphoric Monoester Hydrolases. J Biol Chem 2007 Oct 19;282(42):30373-80
2-phosphoglycolate phosphatase PGLP1, Arabidopsis  EC 3.1.3.18   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Physiol 2007 Jul;144(3):1580-6
GDP-L-galactose phosphorylase, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. J Biol Chem 2007 Jun 29;282(26):18879-85
Gpp1 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Mol Biol 2007 Mar;63(4):505-17
Gpp2 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Mol Biol 2007 Mar;63(4):505-17
5PTase2 protein, Arabidopsis  EC 3.1.3.56   *Phosphoric Monoester Hydrolases. Plant Physiol 2007 Mar;143(3):1408-17
LDP-4 protein, mouse  EC 3.1.3.-   *Nerve Tissue Proteins *Phosphoric Monoester Hydrolases. Mol Cell Biochem 2007 Feb;296(1-2):177-84
Atg5 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Cell Physiol 2006 Dec;47(12):1641-52
OtsB protein, E coli  EC 3.1.3.12   *Phosphoric Monoester Hydrolases *Escherichia coli Proteins. Mol Microbiol 1993 Apr;8(2):205-10
PHOSPHO1 protein, chicken  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Bone 2006 Nov;39(5):1000-7
MTMR14 protein, human  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Hum Mol Genet 2006 Nov 1;15(21):3098-106
UDP-2,4-diacetamido-2,4,6-trideoxy-L-altrose hydrolase, Campylobacter jejuni  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. J Biol Chem 2006 Jul 28;281(30):20902-9
VTC4 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. J Biol Chem 2006 Jun 9;281(23):15662-70
neuroendocrine-associated phosphatase, human  EC 3.1.3.   *Phosphoric Monoester Hydrolases. J Neurochem 2006 Jul;98(1):89-101
CysQ protein, E coli  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. J Bacteriol 1992 Jan;174(2):415-25
lazaro protein, Drosophila  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Drosophila Proteins. Neuron 2006 Feb 16;49(4):533-46
MTH1 protein, mouse  EC 3.1.6.-   *Phosphoric Monoester Hydrolases. J Neurosci 2006 Feb 8;26(6):1688-98
voltage-sensor-containing phosphatase, Ciona intestinalis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Sci STKE 2005 Oct 25;2005(307):pe50
Bst1 protein, S cerevisiae  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Saccharomyces cerevisiae Proteins. Mol Biol Cell 2006 Feb;17(2):834-50
sorbitol-6-phosphatase, Bombyx mori  EC 3.1.3.50   *Phosphoric Monoester Hydrolases. Insect Biochem Mol Biol 2005 Nov;35(11):1284-92
SAC9 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Physiol 2003 Jun;132(2):544-55
Phospho2 protein, human  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Biochim Biophys Acta 2005 Aug 31;1752(1):73-82
Phpt1 protein, rat  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. J Cereb Blood Flow Metab 2002 Dec;22(12):1420-4
PHPT1 protein, human  EC 3.1.3.-   *Phosphoric Monoester Hydrolases. Eur J Biochem 2002 Oct;269(20):5016-23
YSR3 protein, S cerevisiae  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Saccharomyces cerevisiae Proteins.
Dcr2 protein, S cerevisiae  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Saccharomyces cerevisiae Proteins. Eukaryot Cell 2004 Dec;3(6):1627-38
ADP-ribose-1''-monophosphatase, S cerevisiae  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Saccharomyces cerevisiae Proteins. Protein Sci 2005 Mar;14(3):719-26
FRA3 protein, Arabidopsis  0   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Cell 2004 Dec;16(12):3242-59
MTMR6 protein, C elegans  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Caenorhabditis elegans Proteins. Mol Cell Biol 2005 May;25(9):3630-8
5PTase14 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Cell Physiol 2004 Nov;45(11):1720-8
5PTase13 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Cell Physiol 2004 Nov;45(11):1720-8
5PTase12 protein, Arabidopsis  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Arabidopsis Proteins. Plant Cell Physiol 2004 Nov;45(11):1720-8
synaptojanin-1 protein, zebrafish  EC 3.1.3.-   *Phosphoric Monoester Hydrolases *Zebrafish Proteins. J Neurosci 2004 Oct 6;24(40):8641-50
SGPP1 protein, human  EC 3.1.3.-   *Membrane Proteins *Phosphoric Monoester Hydrolases.
SGPP2 protein, human  EC 3.1.3.-   *Membrane Proteins *Phosphoric Monoester Hydrolases.
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