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Purinones

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Definition:      
Examples Hypoxanthines; Xanthines 		Other names Oxopurines
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7-(2,3-dibromo-4,5-dihydroxybenzyl)-3,7-dihydro-1H-purine-2,6-dione  0   *Purinones. J Nat Prod 2007 Mar;70(3):337-41
7-(3-bromo-2-(2,3-dibromo-4,5-dihydroxybenzyl)-4,5-dihydroxybenzyl)-3,7-dihydro-1H-purine-2,6-dione  0   *Purinones. J Nat Prod 2007 Mar;70(3):337-41
7-(2-hydroxy-3-(4-(2-phenoxyethyl)piperazinyl-1-yl)propyl)-1,3-di-methyl-3,7-dihydro-1H-purine-2,6-dione dihydrochloride  0   *Piperazines *Purinones. Pol J Pharmacol 2004 Nov-Dec;56(6):755-66
4-methyl-8-ethyl-2-phenylimidazo(2,1-i)purin-5-one  0   *Imidazoles *Purinones. J Med Chem 2002 Aug 1;45(16):3440-50
1,4-dimethyl-8-ethyl-2-styrylimidazo(2,1-i)purinone  0   *Purinones. J Med Chem 2002 Aug 1;45(16):3440-50
1-benzyl-3-propyl-1H,3H-pyrido(2,1-f)purine-2,4-dione  0   *Purinones Receptors, Purinergic P1/antagonists & inhibitors. J Med Chem 2002 Aug 1;45(16):3337-44
WIN 65579  0   *Purinones *Pyrimidines 3',5'-Cyclic-GMP Phosphodiesterases/antagonists & inhibitors. Eur J Pharmacol 1998 May 22;349(2-3):263-8
2-amino-6,7,8,9-tetrahydro-9-hydroxypyrido(2,1-f)purin-4(3H)-one  0   *Purinones. Chem Res Toxicol 1997 Jul;10(7):772-8
SDZ MKS 492  114606-56-3 1H-Purine-2,6-dione, 8-((1-(3,4-dimethoxyphenyl)-2-hydroxyethyl)amino)-3,7-dihydro-7-(2-methoxyethyl)-1,3-dimethyl-, (R)  *Purinones. Agents Actions Suppl 1991;34:403-10
2-(2-propoxyphenyl)-6-purinone  119409-07-3   *Purinones. Agents Actions Suppl 1991;34:27-46
caissarone  106145-23-7 8H-Purin-8-one, 3,6,7,9-tetrahydro-3,9-dimethyl-6-(methylimino)  *Purinones Cnidarian Venoms Sea Anemones. Toxicon 1986;24(8):751
hydroxy-Y base  70363-52-9 1H-Imidazo(1,2-a)purine-7-butanoic acid, 4,9-dihydro-beta-hydroxy-alpha-((methoxycarbonyl)amino)-4,6-dimethyl-9-oxo-, methyl ester  *Purinones. Nucleic Acids Res 6(3):993;1979
zaprinast  37762-06-4 2-o-propoxyphenyl-8-azapurine-6-one  *Purinones 3',5'-Cyclic-AMP Phosphodiesterases/antagonists & inhibitors 3',5'-Cyclic-GMP Phosphodiesterases/antagonists & inhibitors.
Pharma Action Phosphodiesterase Inhibitors 		Cas Lek Res 116(48):1481;1977; Internat Arch Allergy Appl Immunol 49(6):774;1975; Mol Pharm 14(5):848;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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