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Receptors, Vitronectin

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Definition: Receptors such as INTEGRIN ALPHAVBETA3 that bind VITRONECTIN with high affinity and play a role in cell migration. They also bind FIBRINOGEN; VON WILLEBRAND FACTOR; osteopontin; and THROMBOSPONDINS.  do not confuse with VITRONECTIN RECEPTOR see INTEGRIN ALPHAVBETA3, DF: RECEPT VITRONECTIN   
Examples Integrin alphaVbeta3 		Other names Vitronectin Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SB 273005  0   *Pyridines Receptors, Vitronectin/antagonists & inhibitors. Arthritis Rheum. 2001 Jan;44(1):128-37
SH 306  0   *Pyridines Receptors, Vitronectin/antagonists & inhibitors. J Cell Biochem 2000 Mar;77(2)213-20
DMP 745  0   *Isoxazoles beta-Alanine/*analogs & derivatives Receptors, Vitronectin/antagonists & inhibitors. J Med Chem 2000 Jan 13;43(1):27-40
SC 65811  0   *Aniline Compounds Receptors, Vitronectin/antagonists & inhibitors. Circ Res 1999 Nov 26;85(11):1040-5
SC 64258  0   *Aniline Compounds Receptors, Vitronectin/antagonists & inhibitors. Circ Res 1999 Nov 26;85(11):1040-5
SC 69000  0   *Aniline Compounds Receptors, Vitronectin/antagonists & inhibitors. Circ Res 1999 Nov 26;85(11):1040-5
SB 223245  0   *Acetic Acids *Benzodiazepinones Receptors, Vitronectin/antagonists & inhibitors. Bioorg Med Chem Lett 1999 Jul 5;9(13):1807-12
SB 265123  0   *Acetic Acids *Aminopyridines Receptors, Vitronectin/antagonists & inhibitors. Bioorg Med Chem Lett 1999 Jul 5;9(13):1807-12
nitroaryl ether solfonamide  0   *Nitrophenols *Sulfonamides Receptors, Vitronectin/antagonists & inhibitors. Bioorg Med Chem 1998 Aug;6(8):1185-208
XR 299  0   *Isoxazoles Receptors, Vitronectin/antagonists & inhibitors. J Med Chem 1997 Jan 3;40(1):50-60
XK 002  0   *Peptides, Cyclic Receptors, Vitronectin/antagonists & inhibitors. Lab Invest 1996 Oct;75(4):563-73
XJ 735  0   *Peptides, Cyclic Receptors, Vitronectin/antagonists & inhibitors. Lab Invest 1996 Oct;75(4):563-73
integrin alphavbeta1  0   *Receptors, Vitronectin Receptors, Virus. Proc Natl Acad Sci U S A 1995 Jun 20;92(13):6161-5
kistrin  0   *Peptides Crotalid Venoms Platelet Aggregation Receptors, Vitronectin/antagonists & inhibitors Disintegrins.
Pharma Action Fibrinolytic Agents 		Circulation 1991;83(3):1038
integrin alphaVbeta5  0   *Receptors, Vitronectin Receptors, Vitronectin. J Biol Chem 1990;265(19):11008
osteoclast functional antigen, Cercopithecus aethiops  0   *Receptors, Vitronectin. J Cell Biol 1989;109(4 Pt 1):1817
echistatin  118337-11-4   *Peptides Viper Venoms Receptors, Vitronectin/antagonists & inhibitors.
Pharma Action Platelet Aggregation Inhibitors 		J Biol Chem 1988;263(36):19827

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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