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Receptor, Adenosine A2A

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Definition: A subclass of adenosine A2 receptors found in LEUKOCYTES, the SPLEEN, the THYMUS and a variety of other tissues. It is generally considered to be a receptor for ADENOSINE that couples to the GS, STIMULATORY G-PROTEIN.      Other names Receptors, Adenosine A2A; A2A Receptors, Adenosine; A2A Receptor, Adenosine; Adenosine A2A Receptors; Adenosine A(2A) Receptor; Adenosine A2A Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-amino-4-phenyl-8-pyrrolidin-1-ylmethylindeno(1,2-d)pyrimidin-5-one  0   *Indenes *Pyrimidines Receptor, Adenosine A1 Receptor, Adenosine A2A Purinergic P1 Receptor Antagonists. Chem Res Toxicol 2011 Jul 18;24(7):1012-30
2-amino-4-phenyl-8-(pyrrolidin-1-ylmethyl)-5H-indeno(1,2-d)pyrimidin-5-one  0   *Indenes *Pyrimidines Receptor, Adenosine A1 Receptor, Adenosine A2A. J Med Chem 2010 Nov 25;53(22):8104-15
3-(4-amino-3-methylbenzyl)-7-(2-furyl)-3H-(1,2,3)triazolo(4,5-d)pyrimidine-5-amine  0   *Pyrimidines *Triazoles Receptor, Adenosine A2A/antagonists & inhibitors. Expert Opin Investig Drugs 2009 Nov;18(11):1619-31
GW 328267  0   *Triazoles Adenosine/*analogs & derivatives Receptor, Adenosine A2A/agonists. Bioorg Med Chem Lett 2009 Aug 1;19(15):4471-5
adora2a.2 protein, zebrafish  0   *Zebrafish Proteins *Receptor, Adenosine A2A. Gene Expr Patterns 2009 Mar;9(3):144-51
Adora2a.1 protein, zebrafish  0   *Zebrafish Proteins *Receptor, Adenosine A2A. Gene Expr Patterns 2009 Mar;9(3):144-51
(7-(2-(4-difluorophenyl)-1-piperazinyl)ethyl)-2-(2-furanyl)-7H-pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-amine  0   *Pyrimidines *Triazoles Receptor, Adenosine A2A/antagonists & inhibitors. Psychopharmacology (Berl) 2008 Oct;200(3):393-401
5-oxazol-2-yl-1H-pyrazolo(4,3-b)pyridin-3-ylamine  0   *Oxazoles *Pyrazoles Receptor, Adenosine A2A/antagonists & inhibitors. Org Biomol Chem 2007 Aug 21;5(16):2567-71
6-methyl-7-(1,2,3)triazol-2-yl-1,6-dihydrobenzo(1,2-d-3,4-d')diimidazole  0   *Benzimidazoles *Triazoles Receptor, Adenosine A2A/antagonists & inhibitors. Org Biomol Chem 2007 Aug 21;5(16):2567-71
5-(5-amino-3-(4-fluorophenyl)pyrazin-2-yl)-1-isopropylprydine-2(1H)-one  0   *Aminopyridines *Piperazines Receptor, Adenosine A1/antagonists & inhibitors Receptor, Adenosine A2A/antagonists & inhibitors. J Pharmacol Exp Ther 2007 Nov;323(2):708-19
2-n-butyl-9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine  0   *Triazoles Adenine/*analogs & derivatives Receptor, Adenosine A2A/antagonists & inhibitors. J Med Chem 2005 Nov 3;48(22):6887-96

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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