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Extracellular Signal-Regulated MAP Kinases

More information in Books or onNLM PubMed
Definition: A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.  note specifics   
Examples Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 6; Mitogen-Activated Protein Kinase 7 		Other names MAP Kinases, Extracellular Signal Regulated; Kinases, Extracellular Signal-Regulated; Extracellular Signal Regulated MAP Kinases; Extracellular Signal Regulated Kinases; MAP Kinases, Extracellular Signal-Regulated; Extracellular Signal-Regulated Kinases; ERK MAP Kinases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
vanishin protein, mouse  EC 2.7.1.37   *Extracellular Signal-Regulated MAP Kinases. Biochem J 2005 Apr 15;387(Pt 2):315-24
REKS protein, Xenopus  EC 2.7.1.37   *MAP Kinase Kinase Kinases *Xenopus Proteins *Extracellular Signal-Regulated MAP Kinases.
ERK8 protein, human  EC 2.7.10.-   *Extracellular Signal-Regulated MAP Kinases. J Biol Chem 2002 May 10;277(19):16733-43
Erk7 protein, rat  EC 2.7.1.37   *Extracellular Signal-Regulated MAP Kinases. Mol Cell Biol 1999 Feb;19(2):1301-12
Mapk4 protein, rat  EC 2.7.10.-   *Extracellular Signal-Regulated MAP Kinases. J Neurochem 1996 Mar;66(3):1191-7
PMEK1 protein, Petunia x hybrida  EC 2.7.1.-   *Plant Proteins *Extracellular Signal-Regulated MAP Kinases. Plant Mol Biol 1995 Jan;27(2):339-50
Ras-dependent mitogen-activated protein kinase kinase kinase  EC 2.7.10.-   *MAP Kinase Kinase Kinases *Extracellular Signal-Regulated MAP Kinases Proto-Oncogene Proteins c-raf. J Biol Chem 1994 Sep 16;269(37):22917-20
Rolled protein, Drosophila  EC 2.7.10.-   *Calcium-Calmodulin-Dependent Protein Kinases *Drosophila Proteins *Extracellular Signal-Regulated MAP Kinases. EMBO J 1994 Apr 1;13(7):1628-35

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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