encyclopedia of medical concepts
ψ 
ψ 
ψ 

Receptors, Adrenergic, alpha

More information in Books or onNLM PubMed
Definition: One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.     
Examples Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 		Other names alpha-Adrenergic Receptors; Receptors, alpha-Adrenergic; Adrenergic alpha-Receptors; alpha-Receptors, Adrenergic; alpha Adrenergic Receptors; Receptors, alpha Adrenergic; Adrenergic alpha Receptors; Receptor, Adrenergic, alpha
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(4-(1-(4-fluorophenyl)-5-(1-methyl-1,2,4-triazol-3-yl)-1H-indol-3-yl)-1-piperidinyl)propionitrile  0   *Indoles *Triazoles Receptors, Adrenergic, alpha/antagonists & inhibitors. J Med Chem 2003 Jan 16;46(2):265-83
DU 124183  0   *Imidazoles *Quinolines Receptors, Adrenergic, alpha/agonists. Mol Pharmacol 2002 Jul;62(1):81-9
1,2,3,6-tetrahydro-1-(N-((4-(2-nitrophenyl)piperazin-1-yl)propyl)carboxamido)-4-methyl-6-(3,4-difluorophenyl)-2-oxopyrimidine  0   *Pyrimidinones Receptors, Adrenergic, alpha/antagonists & inhibitors. J Med Chem 1999 Nov 18;42(23):4794-803
1-(N-(3-(4-methyl-4-phenylpiperidin-1-yl)propyl)carboxamido)-6-(3,4-difluorophenyl)-5-methoxycarbonyl-4-methoxymethyl-2-oxo-1,2,3,6-tetrahydropyrimidine  0   *Pyrimidinones Receptors, Adrenergic, alpha/antagonists & inhibitors. J Med Chem 1999 Nov 18;42(23):4778-93
5-carboxamido-1-(N-(3-(4-cyano-4-phenylpiperidin-1-yl)propyl)carboxamido)-6-(2,4-difluorophenyl)-4-ethyl-2-oxo-1,2,3,6-tetrahydropyrimidine  0   *Pyrimidinones Receptors, Adrenergic, alpha/antagonists & inhibitors. J Med Chem 1999 Nov 18;42(23):4778-93
SNAP 6201  0   *Pyrimidinones Receptors, Adrenergic, alpha/antagonists & inhibitors. J Med Chem 1999 Nov 18;42(23):4764-77
5-(N-2'-aminoethyl-N'-isopropyl)amiloride-N-(4''-azidosalicylamide)  144176-48-7   Amiloride/*analogs & derivatives Receptors, Adrenergic, alpha. Mol Pharmacol 1992 Aug;42(2):175-9
5-(N-2'-(4''-azidosalicylamidino)ethyl-N'-isopropyl)amiloride  144176-47-6   Amiloride/*analogs & derivatives Receptors, Adrenergic, alpha. Mol Pharmacol 1992 Aug;42(2):175-9
idazoxan receptor  0   *Receptors, Adrenergic, alpha *Receptors, Drug Idazoxan. J Neurochem 1990;55(1):192

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy