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Subtilisins

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Definition: A family of SERINE ENDOPEPTIDASES isolated from Bacillus subtilis. EC 3.4.21.-  SUBTILISIN is available   
Examples Subtilisin 		Other names Subtilisin, Carlsberg; AprA Subtilisin; Alcalase, Novo; Subtilopeptidase A; Subtilisin Novo; Subtilisin GX; Subtilisin E; Subtilisin DY; Subtilisin Carlsberg; Subtilisin BPN'; Subtilisin A; Subtilisin 72; Protease VII; Profezim; Novo Alcalase; Nagarse; Maxatase; Carlsberg Subtilisin; Bacillus subtilis Alkaline Proteinase; Bacillus amyloliquefaciens Serine Protease
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
subtilisin-like protease SPC6A, Xenopus  EC 3.4.21.-   *Subtilisins *Xenopus Proteins. J Biol Chem. 2009 Oct 2;284(40):27157-66
subtilase cytotoxin, E coli  EC 3.4.21.-   *Subtilisins *Escherichia coli Proteins. Cell Microbiol 2008 Mar;10(3):795-806
MSK103 protein, Bacillus licheniformis  EC 3.4.21.-   *Subtilisins. J Appl Microbiol 2007 Feb;102(2):509-15
subtilisin QK, Bacillus subtilis  EC 3.4.21.-   *Subtilisins. J Biochem Mol Biol 2005 Sep 30;38(5):577-83
IBTC-3 subtilisin, Bacillus subtilis  EC 3.4.21.62   *Subtilisins. Comp Biochem Physiol B Biochem Mol Biol 2005 Feb;140(2):321-31
Pcsk7 protein, rat  EC 3.4.21.-   *Subtilisins.
Pcsk7 protein, mouse  EC 3.4.21.-   *Subtilisins.
PCSK4 protein, human  EC 3.4.21.-   *Subtilisins *Proprotein Convertases.
Flite Tabs  0   *Flavonoids *Subtilisins. Angiology 2003 Sep-Oct;54(5):531-9
Fermosorb.  EC 3.4.-   *Subtilisins.
mycosin-1, Mycobacterium tuberculosis  EC 3.4.21.-   *Bacterial Proteins *Subtilisins. BMC Microbiol 2002 Oct 7;2(1):30
SUB1 protein, Toxoplasma gondii  EC 3.4.21.-   *Subtilisins *Protozoan Proteins. Microbiology 2001 Nov;147(Pt 11):45341-8
subtilisin ALP I  EC 3.4.21.-   *Subtilisins. J Biochem (Tokyo) 2001 May;129(5):675-82
AhSUB protein, Acanthamoeba healyi  EC 3.4.21.-   *Serine Endopeptidases *Protozoan Proteins Subtilisins. Mol Biochem Parasitol 2000 Dec;111(2):441-6
HreP protein, Yersinia enterocolitica  EC 3.4.21.-   *Bacterial Proteins *Subtilisins. J Bacteriol 2001 Jun;183(12):3556-63
subtilisin-like protease 1, Plasmodium falciparum  EC 3.4.21.-   *Subtilisins *Protozoan Proteins. J Biol Chem 2000 Jan 7;275(1):631-41
sub-2 protein, Plasmodium falciparum  EC 3.4.21.-   *Subtilisins Merozoite Surface Protein 1. Proc Natl Acad Sci U S A 1999 May 25;96(11):6445-50
subtilase, plant  EC 3.4.21.-   *Subtilisins Plant Proteins. Plant Mol Biol 1999 Mar;39(4):749-60
subtiligase  EC 6.3.2.-   *Peptide Synthases *Subtilisins. Biochem Biophys Res Commun 1999 Jan 8;254(1):147-51
Aquifex pyrophilus serine-type protease  EC 3.4.21.-   *Subtilisins. J Biol Chem 1999 Jan 8;274(2):881-8
keratinolytic subtilase  EC 3.4.21.-   *Subtilisins. Dermatology 1998;196(4):438-41
M-protease  EC 3.4.21.-   *Subtilisins. Protein Eng 1997 Jun;10(6):627-34
proprotein convertase PC7  EC 3.4.21.-   *Subtilisins Enzyme Precursors. J Biol Chem 1997 Aug 8;272(32):19672-81
serine protease PB92  EC 3.4.21.-   *Subtilisins. J Biomol NMR 1995 Apr;5(3):259-70
PrcA protein, bacteria  0   *Bacterial Proteins *Subtilisins. Eur J Biochem 1996 Nov 1;241(3):750-5
protease SPC7  EC 3.4.21.-   *Subtilisins. J Cell Biol 1996 Jul;134(1):181-91
pathogen-induced protease, P69  EC 3.4.21.-   *Subtilisins. Proc Natl Acad Sci U S A 1996 Jun 25;93(13):6332-7
PCSK7 protein, human  EC 3.4.21.-   *Subtilisins. Biochem Biophys Res Commun 1994 Aug 15;202(3):1452-9; Biochem J 1996 Mar 15;314(Pt 3):727-31; Cancer Res 1996 Feb 1;56(3):448-51
ara12 protein, Arabidopsis  EC 3.4.21.-   *Subtilisins *Arabidopsis Proteins Plant Proteins. Plant Cell 1995 Jun;7(6):785-94
ag12 protein, Alnus glutinosa  EC 3.4.21.-   *Plant Proteins *Subtilisins. Plant Cell 1995 Jun;7(6):785-94
AprS protein, Bacillus  EC 3.4.21.-   *Bacterial Proteins *Subtilisins. Enzyme Microb Technol 1995 Jul;17(7):653-63
bli-4 protein, C elegans  EC 3.4.21.-   *Subtilisins *Caenorhabditis elegans Proteins. Genes Dev 1995 Apr 15;9(8):956-71
macluralisin  EC 3.4.21.-   *Subtilisins Moraceae. Planta 1995;196(1):174-9
afurin 2  EC 3.4.21.-   *Subtilisins. DNA Cell Biol 1995 May;14(5):431-43
Durazym  EC 3.4.21.-   *Subtilisins Recombinant Proteins. Electrophoresis 1994 Dec;15(12):1535-40
protease PACE4C  EC 3.4.21.-   *Subtilisins. Endocrinology 1995 Jan;136(1):357-60
krp dibasic endopeptidase  EC 3.4.21.-   *Subtilisins. EMBO J 1994 Dec 15;13(24):5910-21
AprM protein, Bacillus  EC 3.4.21.-   *Bacterial Proteins *Subtilisins. Appl Environ Microbiol 1994 Oct;60(10):3579-84
CLSI protein, Canavalia lineata  0   *Plant Proteins Subtilisins/antagonists & inhibitors. J Biochem (Tokyo) 1994 Mar;115(3):397-404
benzyloxycarbonyl-alanyl-alanyl-prolyl-phenylalanine-trifluoromethylketone  152551-55-8   *Oligopeptides Subtilisins/antagonists & inhibitors. Biochemistry 1993 Dec 21;32(50):13909-16
NisP protein, Lactococcus lactis  EC 3.4.21.-   *Bacterial Proteins *Membrane Proteins *Subtilisins. J Bacteriol 1993 May;175(9):2578-88
selenosubtilisin  EC 3.4.21.-   *Subtilisins Peroxidases. Biochemistry 1993 Apr 6;32(13):3468-73
AH-101 thermostable alkaline protease  EC 3.4.21.-   *Serine Endopeptidases Bacillus Subtilisins. Appl Microbiol Biotechnol 1992 Oct;38(1):101-8
subtilisin J  120858-57-3   *Subtilisins. Biochem Biophys Res Commun 1992 Oct 15;188(1):184-9
subtilisin inhibitor p20, Oryza sativa  148197-65-3   *Plant Proteins alpha-Amylases/antagonists & inhibitors Subtilisins/antagonists & inhibitors. FEBS Lett 1992 Aug 31;309(1):68-72
dfurin2  148294-73-9   *Subtilisins. J Biol Chem 1992 Aug 25;267(24(4):17208-15
anhydrosubtilisin  EC 3.4.21.-   *Subtilisins. FEBS Lett 1992 Jan 20;296(2):163-5
proteinase R  EC 3.4.21.-   *Subtilisins. Int J Peptide Protein Res 1990;36(4):387
proteinase T  EC 3.4.21.-   *Subtilisins. FEBS Lett 1990;85(2):329
lysosubtilin G10X  EC 3.4.-   *Subtilisins. Antibiot Khimioter 1989;34(8):579
alkaline elastase YaB  EC 3.4.21.-   *Subtilisins. J Bacteriol 1989;171(9):5232
prosubtilisin  117444-15-2   *Enzyme Precursors *Peptide Fragments *Subtilisins. J Biol Chem 1988;263(26):12959
nattokinase  EC 3.4.21.-   *Subtilisins Soy Foods. Experientia 1987;43(10):1110
preprosubtilisin  EC 3.4.21.-   *Enzyme Precursors *Subtilisins. J Biol Chem 1986;261(22):10176
PKI-3 protein, Triticum aestivum  0   *Plant Proteins Amylases/antagonists & inhibitors Subtilisins/antagonists & inhibitors. FEBS Lett 1986;197(1-2):111
N-dansyl-3-aminobenzeneboronic acid  75806-94-9 Boronic acid, (3-(((5-(dimethylamino)-1-naphthalenyl)sulfonyl)amino)phenyl)  *Boronic Acids *Dansyl Compounds Subtilisins/antagonists & inhibitors. Biochem Biophys Res Commun 1980;96(1):157; FEBS Lett 1981;133(1):36
sultilains  EC 3.4.21.-   *Subtilisins. Am Surg 41(9):581;1975; Curr Prob Surg 14(4):20;1977; J Surg Res 17(4):219;1974; Plastic Reconstr Surg 51(4):371;1973TRAVASE
thiolsubtilisins  EC 3.4.21.-   *Subtilisins. Acta Biochim Biophys Acad Sci Hung 11(2-3):81;1976; J Biochem 82:125;1977
subtilisin inhibitor protein, Streptomyces  0   *Bacterial Proteins Subtilisins/antagonists & inhibitors.
Pharma Action Serine Proteinase Inhibitors 		J Biochem (Tokyo) 1980;87(2):483; J Biochem (Tokyo) 84(4):843;1978; J Biochem (Tokyo) 84(4):897;1978; J Biochem (Tokyo) 84(5):1195;1978

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