encyclopedia of medical concepts
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Interleukin-6
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Definition
: A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
DF: IL 6 or IL6
See Also
Hybridomas
;
Plasmacytoma
Other names
Plasmacytoma Growth Factor; Myeloid Differentiation-
Inducing Protein; MGI-
2; IL-
6; Hybridoma Growth Factor; Hepatocyte-
Stimulating Factor; Myeloid Differentiation Inducing Protein; Interleukin 6; Hepatocyte Stimulating Factor; Growth Factor, Plasmacytoma; Growth Factor, Hybridoma; Differentiation-
Inducing Protein, Myeloid; Differentiation Factor, B Cell; Differentiation Factor 2, B Cell; B Cell Stimulatory Factor 2; B Cell Differentiation Factor 2; B Cell Differentiation Factor; IFN-
beta 2; Differentiation Factor-
2, B-
Cell; Differentiation Factor, B-
Cell
Substance
CAS Registry & name
Categories
Source
Drugs
*
duanbanhuain B
0
*Peptides, Cyclic
Interleukin-6/antagonists & inhibitors
Collagen Type IV/antagonists & inhibitors.
Bioorg Med Chem Lett. Dec 15;21(24):7434-9.
duanbanhuain A
0
*Peptides, Cyclic
Interleukin-6/antagonists & inhibitors
Collagen Type IV/antagonists & inhibitors.
Bioorg Med Chem Lett. Dec 15;21(24):7434-9.
quercetin 3-
O-
(2''-
galloyl)glucopyranoside
0
*Glucosides
Quercetin/*analogs & derivatives
Interleukin-6/antagonists & inhibitors.
Cytokine 2007 Sep;39(3):207-15
IL6 protein, human
0
*Interleukin-6.
neuropoietin, mouse
0
*Interleukin-6.
Proc Natl Acad Sci U S A 2004 Apr 6;101(14)4827-32
SANT-
7
0
Interleukin-6/*analogs & derivatives.
Int J Cancer 2001 Sep 1;93(5):674-80
TJU 103
0
*Organic Chemicals
Interferon-gamma/antagonists & inhibitors
Interleukin-1/antagonists & inhibitors
Tumor Necrosis Factor-alpha/antagonists & inhibitors
Interleukin-6/antagonists & inhibitors.
Antimicrob Agents Chemother 2000 Apr;44(4):1067-9
interleukin-
6, RRV-
HHV-
8
0
*Viral Proteins
*Interleukin-6.
J Virol 1999 Jul;73(7):6177-81
2-
amino-
4-
(4-
chlorophenyl)-
5-
methylthiazole
0
*Thiazoles
Interleukin-6/antagonists & inhibitors.
Bioorg Med Chem Lett 1999 Apr 5;9(7):957-60
interleukin 6-
interleukin 6 receptor fusion protein, recombinant
0
*Recombinant Fusion Proteins
*Interleukin-6
*Receptors, Interleukin-6.
Nat Biotechnol 1997 Feb;15(2):142-5
22-
interleukin-
6 cysteine(3,4)
0
*Interleukin-6.
J Chromatogr A 1995 Aug 11;709(1):135-46
CGP 47969A
0
*Piperazines
Interleukin-1/antagonists & inhibitors
Cytokines/antagonists & inhibitors
Tumor Necrosis Factor-alpha/antagonists & inhibitors
Interleukin-6/antagonists & inhibitors.
J Rheumatol 1994 Nov;21(11):1992-7
recombinant fusion protein IL-
6 -
IL-
2
0
*Interleukin-2
*Interleukin-6
Recombinant Fusion Proteins.
Stem Cells (Dayt) 1994 May;12(3):339-47
interleukin-
6, 2-
nitrophenylsulfenyl-
Trp(36,160)
0
Interleukin-6/*analogs & derivatives.
Eur J Biochem 1993 Oct 1;217(1):53-9
DAB(389)-
interleukin 6
0
*Diphtheria Toxin
*Interleukin-6
Recombinant Fusion Proteins.
Protein Eng 1993 Apr;6(3):305-11
interleukin-
6-
PE66(4Glu) chimeric protein, recombinant
0
*Exotoxins
*Recombinant Fusion Proteins
*Interleukin-6
*ADP Ribose Transferases.
Cancer Res 1991;51(11):2831
IL-
6-
PE40 protein, chimeric
0
*Exotoxins
*Recombinant Fusion Proteins
*Interleukin-6
*ADP Ribose Transferases
Bacterial Proteins.
Mol Cell Biol 1990;10(6):2443