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Exotoxins

More information in Books or onNLM PubMed
Definition: Toxins produced, especially by bacterial or fungal cells, and released into the culture medium or environment.  bacterial or fungal toxins; /antag permitted but consider also ANTITOXINS: coord IM with source of exotoxin (IM or NIM)   
Examples Exfoliatins; Streptolysins 		Other names Exotoxin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
immunotoxin HA22  0   *Bacterial Toxins *Exotoxins. Clin Cancer Res 2009 Feb 1;15(3):832-9
transforming growth factor(alpha)-Pseudomonas aeruginosa exotoxin (38)  0   *Exotoxins *Transforming Growth Factor alpha Recombinant Fusion Proteins. Rev Recent Clin Trials 2006 May;1(2):119-31
IL13-PE38  0   *Exotoxins *Recombinant Fusion Proteins *Interleukin-13. Clin Cancer Res 2004 Sep 15;10(18 Pt 1):6231-8
2-O-alpha-L-rhamnopyranosyl-alpha-L-rhamnopyranosyl-alpha(R)-3-hydroxytetradecanoyl-(R)-3-hydroxytetradecanoate  0   *Glycolipids Exotoxins. Biol Chem. 2006 Mar;387(3):301-10
scFv(FRP5)-ETA antibody toxin  0   *Exotoxins *Recombinant Fusion Proteins *Single-Chain Antibodies. Breast Cancer Res 2005;7(5):R617-26
IL13E13K-PE38 protein  0   *Exotoxins *Recombinant Fusion Proteins Interleukin-13/*analogs & derivatives. Clin Cancer Res 2004 Sep 15;10(18 Pt 1):6231-8
IL13-PE38QQR  0   *Exotoxins *Interleukin-13 Immunotoxins. Acta Neurochir Suppl 2003;88:105-11
interleukin-4-Pseudomonas exotoxin  0   *Bacterial Toxins *Exotoxins *Interleukin-4. J Neurooncol 2003 Aug-Sep;64(1-2):125-37
hIL-13-PE38QQR  0   *Exotoxins *Interleukin-13. Curr Opin Investig Drugs 2001 Sep;2(9):1309-13
SpeJ protein, Streptococcus pyogenes  0   *Bacterial Proteins *Exotoxins *Superantigens. Infect Immun 2001 Mar;69(3):1381-8
staphylococcal exotoxin 1  0   *Exotoxins. Mol Biotechnol 2000 May;15(1):11-20
SEGv enterotoxin  0   *Exotoxins Enterotoxins Superantigens. Microbiol Immunol 2000;44(2):79-88
MBP-PE40  0   *Myelin Basic Proteins *Exotoxins *Recombinant Fusion Proteins *ADP Ribose Transferases Immunotoxins. Immunol Lett 1999 Jun 1;68(2-3):403-10
L-GnRH-PE40  0   *Exotoxins. Med Oncol 1999 Apr;16(1):38-45
L-GnRH-PE66 protein, chimeric  0   *Exotoxins *Gonadotropin-Releasing Hormone *Recombinant Fusion Proteins *ADP Ribose Transferases. Med Oncol 1999 Apr;16(1):38-45
SpeA protein, Streptococcus pyogenes  0   *Exotoxins *Membrane Proteins *Bacterial Proteins. J Infect Dis 1999 Mar;179(3):627-36
LukD protein, Staphylococcus aureus  0   *Bacterial Proteins *Exotoxins. FEBS Lett 1998 Oct 2;436(2):202-8
LukE protein, Staphylococcus aureus  0   *Exotoxins *Bacterial Proteins. FEBS Lett 1998 Oct 2;436(2):202-8
BMS-191352 protein, recombinant  0   *Bacterial Toxins *Exotoxins *Recombinant Fusion Proteins *ADP Ribose Transferases *Single-Chain Antibodies Immunotoxins. J Immunoassay 1998 May-Aug;19(2-3):145-65
mitogenic exotoxin Z protein, Streptococcus  0   *Bacterial Toxins *Exotoxins Antigens, Bacterial. Infect Immun 1997 Sep;65(9):3828-33
G28-5 sFv-PE40  0   *Exotoxins Antibodies, Monoclonal Immunotoxins. Blood 1997 Jun 15;89(12):4493-500
heregulin beta1-exotoxin  0   *Exotoxins *Neuregulin-1 Recombinant Fusion Proteins. Int J Cancer 1997 Mar 17;70(6):682-7
HAR-TX beta 2 protein, recombinant  0   *Exotoxins *Glycoproteins Recombinant Fusion Proteins Immunotoxins. J Biol Chem 1995 Mar 31;270(13):7625-30
fuscopeptin A  0   *Peptides, Cyclic Bacterial Toxins Exotoxins. FEBS Lett 1996 Mar 4;381(3):213-6
immunotoxin LMB-7  0   *Antibodies, Monoclonal Exotoxins Immunotoxins. Proc Natl Acad Sci U S A 1995 Mar 28;92(7):2765-9
staphylococcal pyrogenic exotoxin type B  0   *Bacterial Toxins *Exotoxins. Biochemistry 1980 Dec 23;19(26):6204-8
OLX 209  0   *Exotoxins *Single-Chain Antibodies Recombinant Fusion Proteins Immunotoxins. Adv Enzyme Regul 1994;34:119-28
transferrin-PE40  0   *Exotoxins *Transferrin Recombinant Fusion Proteins. Ann N Y Acad Sci 1994 Sep 10;737:138-44
insulin-like growth factor I-Pseudomonas exotoxin A (40)  0   *Exotoxins *Insulin-Like Growth Factor I. J Neurosurg 1993 Oct;79(4):569-76
acidic fibroblast growth factor-Pseudomonas exotoxin A  0   *Exotoxins *Fibroblast Growth Factor 1. J Neurosurg 1993 Oct;79(4):569-76
transforming growth factor alpha-Pseudomonas exotoxin A (40)  0   *Exotoxins *Transforming Growth Factor alpha. J Neurosurg 1993 Oct;79(4):569-76
transforming growth factor(alpha)-Pseudomonas exotoxin A (35)  0   *Exotoxins *Transforming Growth Factor alpha Recombinant Fusion Proteins. J Urol 1993 Jun;149(6):1626-32
Panton-Valentine leukocidin  0   *Bacterial Toxins *Exotoxins *Leukocidins Staphylococcus aureus. Dermatology 1992;185(3):175-80
HS-6, Nocardia  108351-33-3   *Bacterial Toxins *Exotoxins. Mycopathologia 1992 Aug;119(2):115-25
B3(Fv)-PE38KDEL recombinant immunotoxin  0   *Antibodies, Monoclonal Exotoxins Immunotoxins Pseudomonas Recombinant Proteins. Biotechnology 1992 Jun;10(6):682-5
interleukin-6-PE66(4Glu) chimeric protein, recombinant  0   *Exotoxins *Recombinant Fusion Proteins *Interleukin-6 *ADP Ribose Transferases. Cancer Res 1991;51(11):2831
E coli O18 O-specific polysaccharide-toxin A  0   *Exotoxins *Antigens, Bacterial *Bacterial Vaccines Escherichia coli. J Infect Dis 1991;163(5):1040
interleukin 2-PE66(4Glu) protein, recombinant  0   *Exotoxins *Interleukin-2 *Recombinant Fusion Proteins Bacterial Proteins. J Biol Chem 1990;265(27):16311
IL-6-PE40 protein, chimeric  0   *Exotoxins *Recombinant Fusion Proteins *Interleukin-6 *ADP Ribose Transferases Bacterial Proteins. Mol Cell Biol 1990;10(6):2443
LysPE40 exotoxin  0   *Exotoxins. J Biol Chem 1990;265(1):408
transforming growth factor type alpha-Pseudomonas exotoxin A  0   *Exotoxins *Transforming Growth Factor alpha Recombinant Fusion Proteins. FASEB J 1989;3(14):2647
IL-4-PE40 protein, recombinant  0   *Exotoxins *Recombinant Fusion Proteins *Interleukin-4 Bacterial Proteins. Proc Natl Acad Sci USA 1989;86(11):4215
IL-2-PE40 chimeric protein, recombinant  0   *Exotoxins *Interleukin-2 *Recombinant Proteins Immunotoxins Bacterial Proteins. J Immunol 1988;141(12):4224
CD4-Pseudomonas toxin  0   *Exotoxins Recombinant Proteins Immunotoxins Bacterial Proteins Antigens, CD4. Nature 1988;335(6188):369
erythrogenic toxin A receptor  0   *Receptors, Immunologic Exotoxins Streptococcus. Acta Histochem (Suppl) (Jena) 1986;33:17
Pseudomonas exotoxin-epidermal growth factor conjugate  0   *Epidermal Growth Factor *Exotoxins Pseudomonas. J Virol 1984;51(3):650
Staphylococcal pyrogenic exotoxin C  0   *Bacterial Toxins Exotoxins Staphylococcus aureus. Ann Intern Med 1982;96(6):937
erythrogenic toxin  0   *Bacterial Proteins *Exotoxins Cysteine Endopeptidases Pyrogens Superantigens. Pharmacol Ther 1980;11(3):661
Pseudomonas exotoxin binding protein, mouse  0   *Receptors, Cell Surface Exotoxins. Cell 1980;21(3):867
Bitoxibacillin  62628-54-0   Organic Chemicals Exotoxins Insecticides. Prikl Biokhim Mikrobiol 15(5):707;1979
exotoxin from Mycoplasma neurolyticum  0   *Exotoxins. Infection 4(1 suppl):9;1976
staphylococcal alpha-toxin  0   *Bacterial Toxins *Hemolysin Proteins Exotoxins Neurotoxins Staphylococcal Toxoid. Mol Cell Biochem 23(3):143;1979
leukotoxin  0   *Exotoxins Bacterial Toxins Cytotoxins.
Pharma Action Immunosuppressive Agents 		Mikrobiol Zh 40(6):745;1978
toxA protein, Pseudomonas aeruginosa  EC 2.4.2.31   *Bacterial Toxins *Exotoxins *Virulence Factors *ADP Ribose Transferases Antineoplastic Agents. Infect Immun 13(5):1467;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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